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Alex Sparreboom

University System of Ohio

98H指数
842论文数
3.1W被引数
收录论文 192
发表时间
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Zebrafish as a Model Organism of Decitabine-Induced Myelotoxicity斑马鱼作为地西他滨诱导骨髓毒性的模型生物
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errHam, Alexander; Anabtawi, Nadeen; Oyman, Konur; Orwick, Shelley; Buelow, Daelynn R.; Sparreboom, Alex; Blaser, Bradley W.; Baker, Sharyn
err分享
err收藏
Environmental Pollutant PFOS Identified in Untargeted Metabolomics as a Dual Oatp1b Substrate and Inhibitor: Implications for DDI Risk环境污染物PFOS在非靶向代谢组学中被鉴定为Oatp1b的双底物和抑制剂：对DDI风险的启示
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errChowdhury, Anika; Ahmed, Eman; Li, Yang Y. L.; Fetsko, Brian; Orwick, Shelley; Drabison, Thomas; Yang, Yan; Cheng, Xioalin; Sparreboom, Alex; Hu, Shuiying
err分享
err收藏
A Cardiac-Specific Humanized Mouse Model to Evaluate the Disposition of OCT3 Substrates用于评估OCT3底物分布的心脏特异性人源化小鼠模型
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errBoeckman, Mike; Bohnert, Regina; Ahmed, Bagdad; Talebi, Zahra; Ahmed, Eman; Zahedimaram, Pegah; Lemen, Lisa; Wang, Xiangning; Hertlein, Erin; Baker, Sharyn; Addison, Daniel; Schaeffeler, Elke; Schwab, Matthias; Nies, Anne T.; Sparreboom, Alex; Huang, Kevin M.
err分享
err收藏
OATP1B2 Deficiency Aggravates Docetaxel-Induced Neutropenia in a Translationally Relevant Mouse ModelOATP1B2 缺乏加剧多西他赛诱导的小鼠中性粒细胞减少症：一项具有转化相关性的动物模型研究
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errSteiger, Brandon; Buelow, Daelynn R.; Curry, Jack; Orwick, Shelley; Sparreboom, Alex; Baker, Sharyn; Hu, Shuiying
err分享
err收藏
Formulation-Dependent Hepatocellular Transport of Taxanes by OATP1B2: Implications for Drug-Drug Interaction Liabilities With Taxol and AbraxaneOATP1B2介导的紫杉烷类药物制剂依赖性肝细胞转运：紫杉醇和阿布拉辛药物-药物相互作用风险的启示
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errKleinert, Nicholas; Wang, Xinye; Xu, Yue; Ahmed, Eman; Peterson, Blake r.; Sparreboom, Alex; Hu, Shuiying
err分享
err收藏
The Novel OCT3 Inhibitor Peficitinib Attenuates Doxorubicin-Induced Cardiotoxicity新型OCT3抑制剂Peficitinib减轻多柔比星诱导的心脏毒性
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errBoeckman, Mike; Ahmed, Bagdad; Lin, Zhihong; Kumar, Damu Sunil; Ahmed, Eman; Curry, John; Ham, Alexander; Islam, Mohammad N.; Kooti, Fatemeh; Sitte, Harald; Stockner, Thomas; Corps, Kara; Wu, Meng; Peterson, Blake; Baker, Sharyn; Addison, Daniel; Sparreboom, Alex; Huang, Kevin M.
err分享
err收藏
Elucidating the Role of S100A9 in Paclitaxel-Induced Peripheral Neuropathy阐明S100A9在紫杉醇诱导的周围神经病变中的作用
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errWang, Ke; Drabison, Thomas; Buelow, Daelynn; Salunkhe, Amruta; Garrity, Katy; Wang, Xinye; Baker, Sharyn D.; Hu, Shuiying; Sparreboom, Alex; Hammond, Luke; Shin, Grace; Eisenmann, Eric D.
err分享
err收藏
Development of a Translationally Relevant Strategy to Protect Against Paclitaxel-Induced Peripheral Neuropathy开发一种具有临床转化意义的策略以保护 against 紫杉醇诱导的周围神经病变
errJournal of Pharmacology and Experimental Therapeutics
IF3.8
err2026-05-01
err0
PREAI
errWang, Xinye; Drabison, Thomas; Wang, Ke; Salunkhe, Amruta; Garrity, Katy; Hu, Shuiying; Baker, Sharyn D.; Sparreboom, Alex; Hammond, Luke; Shin, Grace; Eisenmann, Eric D.
err分享
err收藏
Ribociclib is not a substrate or inhibitor of Oatp1b-mediated uptake in vivo瑞博西尼（Ribociclib）不是Oatp1b介导的内吞作用的底物或抑制剂。
errCancer Chemotherapy and Pharmacology
IF2.3
err2026-04-07
err0
errOAAI
errThomas Drabison; Eman A. Ahmed; Nathan Colasanti; Robert H. Weber; Alex Sparreboom; Eric D. Eisenmann
err分享
err收藏
Pacific Blue Derivatives of Paclitaxel as Fluorescent Probes of OATP1B-Type Transporters
errClinical and Translational Science
IF2.8
err2026-01-27
err0
errOAAI
errMahesh R. Nepal; Yue Xu; Yan Jin; Peng Hu; Xiaojun Hu; Digamber S. Rane; Angelo E. Andres; Eman A. Ahmed; Brandon Steiger; Alex Sparreboom; Blake R. Peterson; Shuiying Hu
err分享
err收藏
Role of SLC transporters in the biodistribution and toxicity of chemotherapeutic drugsSLC转运蛋白在化疗药物的生物分布和毒性中的作用
errPharmacological Reviews
IF17.3
err2026-01-16
err0
errOAAI
errMike Boeckman; Thomas Drabison; Arthur Germakovski; Allison Warmuth; Bagdad Ahmed; Anika Chowdhury; Shuiying Hu; Jason A. Sprowl; Alex Sparreboom; Kevin M. Huang
err分享
err收藏
OATP2B1 Deficiency Ameliorates Irinotecan-Induced Gastrointestinal Toxicity
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2025-12-29
err0
errOAAI
errTaheri, Hanieh; de Bruijn, Peter; Li, Yang; Kleinert, Nicholas R.; Corps, Kara N.; Mathijssen, Ron H. J.; Huang, Kevin M.; Sparreboom, Alex; Hu, Shuiying
err分享
err收藏
Drug–drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors靶向癌症治疗中的药物-药物相互作用：聚焦于酪氨酸激酶抑制剂
errExpert Review of Clinical Pharmacology
IF3
err2025-12-24
err0
errOAAI
errJack C. Stromatt; Anika T. Chowdhury; Kevin M. Huang; Shuiying Hu; Alex Sparreboom; Sharyn D. Baker; Eric D. Eisenmann
err分享
err收藏
Regulation of hepatic OATP1B-type transport function by the protein kinase LYN肝OATP1B型转运蛋白功能的蛋白激酶LYN调控
errDrug Metabolism and Disposition
IF4
err2025-07-30
err0
PREAI
errVivian Xu; Mahesh R. Nepal; Eman Ahmed; Benjamin D. Kaczynski; Yue Xu; James M. Gallo; Kevin M. Huang; Alex Sparreboom; Shuiying Hu; Jason A. Sprowl
err分享
err收藏
Determination and Disposition of the Aromatase Inhibitor Exemestane in CYP3A-Deficient Mice
errMOLECULES
IF4.6
err2025-03-24
err0
errOAAI
errTaheri, Hanieh; Ahmed, Eman; Hu, Peng; Sparreboom, Alex; Hu, Shuiying
err分享
err收藏
AML-Dependent Transcriptional Repression of Hepatic TransportersAML介导的肝转运蛋白转录抑制
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errStromatt, Jack C.; Orwick, Shelley; Buelow, Daelynn R.; Pabla, Navjot S.; Sparreboom, Alex; Baker, Sharyn D.
err分享
err收藏
P-glycoprotein (P-gp) Deficiency Exacerbates Vincristine-Induced Peripheral NeuropathyP-糖蛋白（P-gp）缺乏会加剧长春新碱诱导的周围神经病变
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errChowdhury, Anika; Drabison, Thomas; Ahmed, Eman; Buelow, Daelynn R.; Peterson, Blake R.; Huang, Kevin M.; Eisenmann, Eric D.; Kulkarni, Chetan P.; Kroetz, Deanna; Baker, Sharyn D.; Sparreboom, Alex; Hu, Shuying
err分享
err收藏
Interaction of Neuropathic Tubulin Poison Payloads with OATP1B-type Transporters神经病理微管毒素有效载荷与OATP1B型转运蛋白的相互作用
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errHuang, Kevin; Jakate, Anushree; Partey, Alexandra; Hu, Shuying; Sparreboom, Alex
err分享
err收藏
Identification of OCT3 Inhibitors for Preventing Cardiac Accumulation of Toxic SubstratesOCT3 抑制剂的鉴定：用于预防毒性底物在心脏中的蓄积
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errBoeckman, Mike; Lin, Zhihong; Huang, Kevin M.; Steenrod, Levi; Wu, Meng; Peterson, Blake R.; Baker, Sharyn D.; Addison, Daniel; Sparreboom, Alex
err分享
err收藏
Targeting S100A9 to Protect Against Paclitaxel-Induced Peripheral Neuropathy靶向S100A9以保护 Against 紫杉醇诱导的周围神经病变
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2025-03-01
err0
PREAI
errDrabison, Thomas; Li, Yang; Buelow, Daelynn R.; Ahmed, Eman; Colasanti, Nathan; Lopatin, Sergey; Baker, Sharyn D.; Hu, Shuiying; Sparreboom, Alex; Eisenmann, Eric D.
err分享
err收藏

研究方向

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