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Thomas A. Baillie

pfizer usa

63H指数
247论文数
1.6W被引数
收录论文 45
发表时间
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Approaches to mitigate the risk of serious adverse reactions in covalent drug design
errEXPERT OPINION ON DRUG DISCOVERY
IF4.9
err2020-10-19
err31
PREAI
errBaillie, Thomas A.
err分享
err收藏
Pharmacokinetic and Metabolic Profile of Deutetrabenazine (TEV-50717) Compared With Tetrabenazine in Healthy Volunteers
errCTS-CLINICAL AND TRANSLATIONAL SCIENCE
IF2.8
err2020-03-10
err30
errOAAI
errSchneider, Frank; Bradbury, Margaret; Baillie, Thomas A.; Stamler, David; Hellriegel, Edward; Cox, Donna S.; Loupe, Pippa S.; Savola, Juha-Matti; Rabinovich-Guilatt, Laura
err分享
err收藏
Targeted Covalent Inhibitors for Drug Design靶向共价抑制剂的药物设计
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2016-08-19
err425
PREAI
errBaillie, Thomas A.
err分享
err收藏
The contributions of Sidney D. Nelson to drug metabolism research
errDRUG METABOLISM REVIEWS
IF3.8
err2014-11-20
err5
PREAI
errBaillie, Thomas A.
err分享
err收藏
The Generation, Detection, and Effects of Reactive Drug Metabolites
errMEDICINAL RESEARCH REVIEWS
IF11.6
err2012-10-22
err73
PREAI
errStachulski, Andrew V.; Baillie, Thomas A.; Park, B. Kevin; Obach, R. Scott; Dalvie, Deepak K.; Williams, Dominic P.; Srivastava, Abhishek; Regan, Sophie L.; Antoine, Daniel J.; Goldring, Christopher E. P.; Chia, Alvin J. L.; Kitteringham, Neil R.; Randle, Laura E.; Callan, Hayley; Castrejon, J. Luis; Farrell, John; Naisbitt, Dean J.; Lennard, Martin S.
err分享
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An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway
errMOLECULAR PHARMACOLOGY
IF3
err2012-04-01
err98
errOAAI
errWang, Zhican; Lin, Yvonne S.; Zheng, Xi Emily; Senn, Tauri; Hashizume, Takanori; Scian, Michele; Dickmann, Leslie J.; Nelson, Sidney D.; Baillie, Thomas A.; Hebert, Mary F.; Blough, David; Davis, Connie L.; Thummel, Kenneth E.
err分享
err收藏
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2011-07-11
err574
PREAI
errStepan, Antonia F.; Walker, Daniel P.; Bauman, Jonathan; Price, David A.; Baillie, Thomas A.; Kalgutkar, Amit S.; Aleo, Michael D.
err分享
err收藏
Managing the challenge of chemically reactive metabolites in drug development
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2011-04-01
err403
PREAI
errPark, B. Kevin; Boobis, Alan; Clarke, Stephen; Goldring, Chris E. P.; Jones, David; Kenna, J. Gerry; Lambert, Craig; Laverty, Hugh G.; Naisbitt, Dean J.; Nelson, Sidney; Nicoll-Griffith, Deborah A.; Obach, R. Scott; Routledge, Philip; Smith, Dennis A.; Tweedie, Donald J.; Vermeulen, Nico; Williams, Dominic P.; Wilson, Ian D.; Baillie, Thomas A.
err分享
err收藏
The resurgence of covalent drugs
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2011-04-01
err1.6K
errOAAI
errSingh, Juswinder; Petter, Russell C.; Baillie, Thomas A.; Whitty, Adrian
err分享
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Approaches to the Assessment of Stable and Chemically Reactive Drug Metabolites in Early Clinical Trials
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2009-02-16
err47
PREAI
errBaillie, Thomas A.
err分享
err收藏
Addressing metabolic activation as an integral component of drug design
errDRUG METABOLISM REVIEWS
IF3.8
err2008-10-09
err45
PREAI
errDoss, George A.; Baillie, Thomas A.
err分享
err收藏
Metabolism and toxicity of drugs. Two decades of progress in industrial drug metabolism
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2007-12-04
err172
errOAAI
errBaillie, Thomas A.
err分享
err收藏
Complicating factors in safety testing of drug metabolites: Kinetic differences between generated and preformed metabolites
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2006-12-01
err59
PREAI
errPrueksaritanont, Thomayant; Lin, Jiunn H.; Baillie, Thomas A.
err分享
err收藏
Future of toxicology-metabolic activation and drug design: Challenges and opportunities in chemical toxicology
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2006-05-28
err138
PREAI
errBaillie, Thomas A.
err分享
err收藏
Drug-protein adducts: An industry perspective on minimizing the potential for drug bioactivation in drug discovery and development (vol 17, pg 3, 2004)
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2005-10-08
err6
PREAI
errEvans, DC; Watt, AP; Nicoll-Griffith, DA; Baillie, TA
err分享
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Zafirlukast metabolism by cytochrome P450 3A4 produces an electrophilic α,β-unsaturated iminium species that results in the selective mechanism-based inactivation of the enzyme
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2005-08-12
err63
PREAI
errKassahun, K; Skordos, K; McIntosh, I; Slaughter, D; Doss, GA; Baillie, TA; Yost, GS
err分享
err收藏
Bioactivation of 2,3-diaminopyridine-containing bradykinin B1 receptor antagonists:: Irreversible binding to liver microsomal proteins and formation of glutathione conjugates
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2005-05-25
err30
PREAI
errTang, C; Subramanian, R; Kuo, Y; Krymgold, S; Lu, P; Kuduk, SD; Ng, C; Feng, DM; Elmore, C; Soli, E; Ho, J; Bock, MG; Baillie, TA; Prueksaritanont, T
err分享
err收藏
Bridging cheminformatic metabolite prediction and tandem mass spectrometry
errDRUG DISCOVERY TODAY
IF7.5
err2005-05-01
err59
PREAI
errAnari, MR; Baillie, TA
err分享
err收藏
Mechanistic studies on the metabolic scission of thiazolidinedione derivatives to acyclic thiols
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2005-04-14
err28
PREAI
errReddy, VBG; Karanam, BV; Gruber, WL; Wallace, MA; Vincent, SH; Franklin, RB; Baillie, TA
err分享
err收藏
Negative ion tandem mass spectrometry for the detection of glutathione conjugates
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2005-03-09
err205
PREAI
errDieckhaus, CM; Fernández-Metzler, CL; King, R; Krolikowski, PH; Baillie, TA
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
K
Kenneth E. Thummel
H 指数: 85 · 论文数: 333
A
Alan R. Boobis
H 指数: 85 · 论文数: 511
R
R. Scott Obach
H 指数: 83 · 论文数: 303
I
Ian D. Wilson
H 指数: 82 · 论文数: 561
E
Evan D. Kharasch
H 指数: 72 · 论文数: 464
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