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Bao Cheng

sun yat-sen university

H指数:16

被引数:573

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Lipocalin 2 (LCN2) confers acquired resistance to almonertinib in NSCLC through LCN2-MMP-9 signaling pathway

PHARMACOLOGICAL RESEARCH

IF10.5

2024-03-011

OAAI

Antitumor activity of aumolertinib, a third-generation EGFR tyrosine kinase inhibitor, in non-small-cell lung cancer harboring uncommon EGFR mutations

第三代EGFR酪氨酸激酶抑制剂aumolertinib在具有罕见EGFR突变的非小细胞肺癌中的抗肿瘤活性

ACTA PHARMACEUTICA SINICA B

IF14.6

2023-06-013

OAAI

Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-11-176

PRE

Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-04-0115

PRE

Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2022-01-0110

PRE

Structure-guided optimization and mechanistic study of a class of quinazolinone-threonine hybrids as antibacterial ThrRS inhibitors

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-12-0111

PREAI

Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2020-02-0120

PREAI

Design, synthesis, and biological evaluation of compounds with a new scaffold as anti-neuroinflammatory agents for the treatment of Alzheimer's disease

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-04-0127

PREAI

Dihydrofisetin exerts its anti-inflammatory effects associated with suppressing ERK/p38 MAPK and Heme Oxygenase-1 activation in lipopolysaccharide-stimulated RAW 264.7 macrophages and carrageenan-induced mice paw edema

INTERNATIONAL IMMUNOPHARMACOLOGY

IF4.7

2018-01-0146

PREAI

Design, syntheses and lipid accumulation inhibitory activities of novel resveratrol mimics

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2018-01-0114

PREAI

Gallocatechin gallate (GCG) inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling

没食子儿茶素没食子酸酯 (GCG) 通过MAPK和nf-κb信号抑制3T3-L1分化和脂多糖诱导的炎症

JOURNAL OF FUNCTIONAL FOODS

IF4

2017-03-0124

PREAI

Discovering new mTOR inhibitors for cancer treatment through virtual screening methods and in vitro assays

SCIENTIFIC REPORTS

IF3.9

2016-01-0658

OAAI

Synthesis and Anti-neuroinflammatory Activity of Lactone Benzoyl Hydrazine and 2-nitro-1-phenyl-1 H-Indole Derivatives as p38α MAPK Inhibitors

CHEMICAL BIOLOGY & DRUG DESIGN

IF3.3

2015-06-0117

PREAI

Preparation of Ag2O/PbO and Ag/PbO nanostructure by direct thermolyses of a metal-organic framework

CHEMICAL ENGINEERING JOURNAL

IF13.2

2014-08-014

PREAI

A new monoterpenoid indole alkaloid from Rauvolfia yunnanensis

CHINESE CHEMICAL LETTERS

IF8.9

2009-10-015

PREAI

Optimization of Novel Quinazolines as Potent Aurora Kinase Inhibitors for Triple-Negative Breast Cancer Treatment

新型喹唑啉类化合物作为强效Aurora激酶抑制剂在治疗三阴性乳腺癌中的应用优化

Journal of Medicinal Chemistry

IF6.8

0

PRE