未登录

周

周志 (Zhi Zhou)

guangzhou medical university

H指数:30

被引数:2,929

个人简介

暂无内容

教育背景

暂无内容

工作经历

暂无内容

荣誉奖项

暂无内容

Umpolung at the meta-Positions of Oxazino-Pyridines Enabling Nucleophilic Pyridine Functionalization

在恶嗪基-吡啶的间位进行极性反转以实现吡啶的亲核官能化

Angewandte Chemie-International Edition

IF16.9

2026-09-140

PRE

Radical enantioconvergent meta-C─H alkylation of pyridines

吡啶的自由基对映选择性间位C─H烷基化

Science Advances

IF12.5

2026-09-110

OA

Calcium(II)-Catalyzed Three-Component Alkoxyselenation of Allenes with Selenium–Nitrogen Exchange (SeNEx) Reagents

钙(II)催化的三组分烯丙基硒醚化反应，使用硒-氮交换（SeNEx）试剂

Organic Letters

IF5

2026-06-080

PRE

Bioinspired Alkyl Transfer Enabled by Ca(II)/HFIP Cooperative Catalysis: Modular Synthesis of Functionalized Isoindolinones

仿生烷基转移由Ca(II)/HFIP协同催化实现：功能化异吲哚啉酮的模块化合成

Organic Letters

IF5

2026-04-100

PRE

Hexafluoroisopropanol-Mediated Cascade Cyclization for Construction of α-Amino-γ-spirolactones

六氟异丙醇催化的级联环化反应构建α-氨基-γ-螺内酯

IF8.7

2025-10-010

PRE

Rh(III)-Catalyzed Direct C–H Selenylation/Cyclization of Benzylamines with Elemental Selenium for the Rapid Construction of Benzoisoselenazole Frameworks

Rh(III)-催化的苄胺与单质硒的直接C–H硒化/环化反应，用于快速构建苯并异硒唑骨架

Organic Letters

IF5

2025-07-310

PRE

Synthesis of Well-Defined Side-Chain Amino Acid-Based Glycopolymers via Postpolymerization Modification: The Synergistic Effect of Amino Acids on Con A Recognition

通过后聚合修饰合成结构明确的侧链氨基酸基糖聚合物：氨基酸对凝集素Con A识别的协同效应

Journal of Polymer Science

IF3.6

2025-07-300

PRE

Synergetic Cp*Rh(III)/Zn2+-Prompted Arylamination of Alkylalkenes: Reaction Development and Mechanistic Insight

协同Cp*Rh(III)/Zn2+-促进的芳基烷烃化作用：反应开发与机理研究

IF13.1

2025-07-230

PRE

Unlocking redox-active reactivity of dearomatized pyridines with photochemistry toward meta-C–H functionalization of pyridines

通过光化学手段解锁去芳香化吡啶的氧化还原活性，实现吡啶的间位C–H键官能化

IF11.6

2025-03-170

PRE

Disproportionality analysis of vibegron-associated adverse events using the FDA adverse event reporting system (FAERS): a real-world pharmacovigilance study

使用FDA不良事件报告系统（FAERS）对维贝格隆相关不良事件进行不成比例性分析：一项真实世界药物警戒研究

EUROPEAN JOURNAL OF MEDICAL RESEARCH

IF3.4

2025-02-270

OA

Recent advances and therapeutic applications of PPARγ-targeted ligands based on the inhibition mechanism of Ser273 phosphorylation

METABOLISM-CLINICAL AND EXPERIMENTAL

IF11.9

2025-02-010

PRE

Electrocatalytic Enantioselective Tandem C-H Indolization toward Biindolyl Atropisomers: Reaction Development and Mechanistic Insight

电催化手性选择性串联C-H吲哚化制备联吲哚基阿托匹斯omers：反应开发与机理洞察

IF13.1

2025-01-090

PRE

Identification of Novel Organo-Se BTSA-Based Derivatives as Potent, Reversible, and Selective PPARγ Covalent Modulators for Antidiabetic Drug Discovery

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2024-12-200

PRE

Chemo-/Regioselective [5+1] Annulation with gem-Difluoromethylene Allenes for the Assembly of Fluorinated 2H-Chromenes and Dihydroquinolines

化学/区域选择性 [5 1] 与宝石-二氟亚甲基烯形成环，用于组装氟化的2h-色烯和二氢喹啉

ADVANCED SYNTHESIS & CATALYSIS

IF4

2024-12-120

PRE

Discovery of an enantiopure N -[2-hydroxy-3-phenyl piperazine propyl]-aromatic carboxamide derivative as highly selective α1D/1A-adrenoceptor antagonist and homology modelling

CHINESE CHEMICAL LETTERS

IF8.9

2024-11-010

PRE

Identification of Novel PPARγ Partial Agonists Based on Virtual Screening Strategy: In Silico and In Vitro Experimental Validation

基于虚拟筛选策略的新型ppar γ 部分激动剂的鉴定: 计算机和体外实验验证

IF4.6

2024-10-150

OAAI

Structure-based screening, optimization and biological evaluation of novel chrysin-based derivatives as selective PPARγ modulators for the treatment of T2DM and hepatic steatosis

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-10-013

PRE

Ring Transformation of Cyclopropenes to Benzo-Fused Five-Membered Oxa- and Aza-Heterocycles via a Formal [4+1] Cyclization

ADVANCED SCIENCE

IF14.1

2024-08-290

OAAI

Assembly of Selenadiazine Scaffolds via Rh(III)-Catalyzed Amidine-Directed Cascade C-H Selenylation/[5+1] Annulation with Elemental Selenium

ORGANIC LETTERS

IF5

2024-08-011

PRE

Catalyst-Free synthesis of sulfonamide-functionalized Poly(phosphonate)s and Poly(phosphate)s using Bis(aziridine)s

EUROPEAN POLYMER JOURNAL

IF6.3

2024-08-010

PRE

研究方向

有机融合，同时结合计算机辅助药物设计药物化学有机合成化学分子药理学基于核受体蛋白的靶向创新药物设计现代药物合成新方法及技术DNA编码化合物库(DELs)药学官能团引入糠酸莫米松(MF)VSP-51复合物晶体结构靶向GR候选新药化合物靶向PPARγ候选新药化合物抗II型糖尿病新药发现VSP-51-2VSP-77及抗菌药物-芬替康唑以GR为靶点的新型配体作为抗炎新药发现：VSP-22

H 指数:47论文数:385被引数:9,652

H 指数:41论文数:333被引数:8,598

H 指数:16论文数:60被引数:1,028

H 指数:21论文数:115被引数:1,752

H 指数:15论文数:48被引数:763

H 指数:22论文数:64被引数:1,640

H 指数:24论文数:100被引数:1,514

H 指数:6论文数:17被引数:154

H 指数:64论文数:381被引数:1.8万

H 指数:11论文数:23被引数:451