Lauren Young - Publications, H-index & Citations

Lauren Young

Monash University

21H指数

81论文数

5.1K被引数

收录论文 22

发表时间

Identification of pre-existing neoantigen-specific T cells in patients receiving checkpoint inhibitor therapy using a deep learning antigen prediction model

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Palmer, Christine D.; Bulik, Brendan; Yang, Aaron; Hart, Meghan; Davis, Matthew; Francis, Joshua; Duke, Fujiko; Zhou, Rita; Busby, Jennifer; Murphy, Tyler; Clark, Andrew; Young, Lauren; Zhong, Mike; Caldwell, Kamilah; Abhyankar, Jesse; Cook, Alison; Boucher, Tommy; Rousseau, Raphael; Voong, Cynthia; Rizvi, Naiyer; Frattini, Mark; Yelensky, Roman; Jooss, Karin; Skoberne, Mojca

MHC class II antigen identification for cancer immunotherapy by deep learning on tumor HLA peptides

CANCER RESEARCH

IF16.6

2019-07-01

PREAI

Boucher, Tommy; Davis, Matthew; Palmer, Christine; Murphy, Tyler; Clark, Andrew; Duke, Fujiko; Yang, Aaron; Young, Lauren; Jooss, Karin; Skoberne, Mojca; Francis, Josh; Yelensky, Roman; Sun, James; Busby, Jennifer

Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification

NATURE BIOTECHNOLOGY

IF41.7

2018-12-17

215

PREAI

Bulik-Sullivan, Brendan; Busby, Jennifer; Palmer, Christine D.; Davis, Matthew J.; Murphy, Tyler; Clark, Andrew; Busby, Michele; Duke, Fujiko; Yang, Aaron; Young, Lauren; Ojo, Noelle C.; Caldwell, Kamilah; Abhyankar, Jesse; Boucher, Thomas; Hart, Meghan G.; Makarov, Vladimir; De Montpreville, Vincent Thomas; Mercier, Olaf; Chan, Timothy A.; Scagliotti, Giorgio; Bironzo, Paolo; Novello, Silvia; Karachaliou, Niki; Rosell, Rafael; Anderson, Ian; Gabrail, Nashat; Hrom, John; Limvarapuss, Chainarong; Choquette, Karin; Spira, Alexander; Rousseau, Raphael; Voong, Cynthia; Rizvi, Naiyer A.; Fadel, Elie; Frattini, Mark; Jooss, Karin; Skoberne, Mojca; Francis, Joshua; Yelensky, Roman

Antigen identification for cancer immunotherapy by deep learning on tumor HLA peptides

CANCER RESEARCH

IF16.6

2018-07-01

PREAI

Bulik-Sullivan, Brendan; Busby, Jennifer; Davis, Matthew; Young, Lauren; Murphy, Tyler; Clark, Andrew; Duke, Fujiko; Busby, Michele; Derti, Adnan; Skoberne, Mojca; Jooss, Karin; Gustafson, Corinne E.; De Rienzo, Assunta; Richards, William G.; Dao, Nhien T.; Kim, Hyeong R.; Anderson, Jamie E.; Choi, Chang-Min; De Montpreville, Vincent; Jang, Se Jin; Mercier, Olaf; Bueno, Raphael; Fadel, Elie; Francis, Joshua; Yelensky, Roman

Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury (vol 24, pg 239, 2018)抑制黄体生成素增强造血损伤后HSC的恢复 (vol 24，pg 239，2018)

NATURE MEDICINE

IF50

2018-04-01

OAAI

Velardi, Enrico; Tsai, Jennifer J.; Radtke, Stefan; Cooper, Kirsten; Argyropoulos, Kimon V.; Jae-Hung, Shieh; Young, Lauren F.; Lazrak, Amina; Smith, Odette M.; Lieberman, Sophie; Kreines, Fabiana; Shono, Yusuke; Wertheimer, Tobias; Jenq, Robert R.; Hanash, Alan M.; Narayan, Prema; Lei, Zhenmin; Moore, Malcolm A.; Kiem, Hans-Peter; van den Brink, Marcel R. M.; Dudakov, Jarrod A.

Production of BMP4 by endothelial cells is crucial for endogenous thymic regeneration 内皮细胞产生BMP4对于内源性胸腺再生至关重要

SCIENCE IMMUNOLOGY

IF16.3

2018-01-26

100

OAAI

Wertheimer, Tobias; Velardi, Enrico; Tsai, Jennifer; Cooper, Kirsten; Xiao, Shiyun; Kloss, Christopher C.; Ottmueller, Katja J.; Mokhtari, Zeinab; Brede, Christian; deRoos, Paul; Kinsella, Sinead; Palikuqi, Brisa; Ginsberg, Michael; Young, Lauren F.; Kreines, Fabiana; Lieberman, Sophia R.; Lazrak, Amina; Guo, Peipei; Malard, Florent; Smith, Odette M.; Shono, Yusuke; Jenq, Robert R.; Hanash, Alan M.; Nolan, Daniel J.; Butler, Jason M.; Beilhack, Andreas; Manley, Nancy R.; Rafe, Shahin; Dudakov, Jarrod A.; van den Brink, Marcel R. M.

Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury 抑制黄体生成素促进造血损伤后HSC的恢复

NATURE MEDICINE

IF50

2018-01-08

OAAI

Sublethal Total Body Irradiation Causes Long-Term Deficits in Thymus Function by Reducing Lymphoid Progenitors

JOURNAL OF IMMUNOLOGY

IF3.4

2017-10-15

OAAI

Xiao, Shiyun; Shterev, Ivo D.; Zhang, Wen; Young, Lauren; Shieh, Jae-Hung; Moore, Malcolm; van den Brink, Marcel; Sempowski, Gregory D.; Manley, Nancy R.

Donor CD19 CAR T cells exert potent graft-versus-lymphoma activity with diminished graft-versus-host activity 供体CD19 CAR T细胞发挥有效的移植物抗淋巴瘤活性，移植物抗宿主活性降低

Nature Medicine

IF50

2017-01-09

191

OAAI

Ghosh, Arnab; Smith, Melody; James, Scott E.; Davila, Marco L.; Velardi, Enrico; Argyropoulos, Kimon V.; Gunset, Gertrude; Perna, Fabiana; Kreines, Fabiana M.; Levy, Emily R.; Lieberman, Sophie; Jay, Hillary V.; Tuckett, Andrea Z.; Zakrzewski, Johannes L.; Tan, Lisa; Young, Lauren F.; Takvorian, Kate; Dudakov, Jarrod A.; Jenq, Robert R.; Hanash, Alan M.; Motta, Ana Carolina F.; Murphy, George F.; Liu, Chen; Schietinger, Andrea; Sadelain, Michel; van den Brink, Marcel R. M.

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice 人类患者和小鼠异基因造血干细胞移植后使用广谱抗生素增加GVHD相关死亡率

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2016-05-18

416

OAAI

Shono, Yusuke; Docampo, Melissa D.; Peled, Jonathan U.; Perobelli, Suelen M.; Velardi, Enrico; Tsai, Jennifer J.; Slingerland, Ann E.; Smith, Odette M.; Young, Lauren F.; Gupta, Jyotsna; Lieberman, Sophia R.; Jay, Hillary V.; Ahr, Katya F.; Rodriguez, Kori A. Porosnicu; Xu, Ke; Calarfiore, Marco; Poeck, Hendrik; Caballero, Silvia; Devlin, Sean M.; Rapaport, Franck; Dudakov, Jarrod A.; Hanash, Alan M.; Gyurkocza, Boglarka; Murphy, George F.; Gomes, Camilla; Liu, Chen; Moss, Eli L.; Falconer, Shannon B.; Bhatt, Ami S.; Taur, Ying; Pamer, Eric G.; van den Brink, Marcel R. M.; Jenq, Robert R.

Enhanced Hematopoietic Stem Cell Function Mediates Immune Regeneration following Sex Steroid Blockade 增强的造血干细胞功能介导性类固醇阻断后的免疫再生

STEM CELL REPORTS

IF5.1

2015-03-01

OAAI

Khong, Danika M.; Dudakov, Jarrod A.; Hammett, Maree V.; Jurblum, Marc I.; Khong, Sacha M. L.; Goldberg, Gabrielle L.; Ueno, Tomoo; Spyroglou, Lisa; Young, Lauren F.; van den Brink, Marcel R. M.; Boyd, Richard L.; Chidgey, Ann P.

Sex steroid blockade enhances thymopoiesis by modulating Notch signaling 性类固醇阻断通过调节Notch信号增强胸腺生成

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2014-10-20

100

OAAI

Velardi, Enrico; Tsai, Jennifer J.; Holland, Amanda M.; Wertheimer, Tobias; Yu, Vionnie W. C.; Zakrzewski, Johannes L.; Tuckett, Andrea Z.; Singer, Natalie V.; West, Mallory L.; Smith, Odette M.; Young, Lauren F.; Kreines, Fabiana M.; Levy, Emily R.; Boyd, Richard L.; Scadden, David T.; Dudakov, Jarrod A.; van den Brink, Marcel R. M.

Linkage between Dendritic and T Cell Commitments in Human Circulating Hematopoietic Progenitors

JOURNAL OF IMMUNOLOGY

IF3.4

2014-06-15

OAAI

Kyoizumi, Seishi; Kubo, Yoshiko; Kajimura, Junko; Yoshida, Kengo; Hayashi, Tomonori; Nakachi, Kei; Young, Lauren F.; Moore, Malcolm A.; van den Brink, Marcel R. M.; Kusunoki, Yoichiro

PLZF Confers Effector Functions to Donor T Cells That Preserve Graft-versus-Tumor Effects while Attenuating GVHD

CANCER RESEARCH

IF16.6

2013-07-31

OAAI

Ghosh, Arnab; Holland, Amanda M.; Dogan, Yildirim; Yim, Nury L.; Rao, Uttam K.; Young, Lauren F.; West, Mallory L.; Singer, Natalie V.; Lee, Hae; Na, Il-Kang; Tsai, Jennifer J.; Jenq, Robert R.; Penack, Olaf; Hanash, Alan M.; Lezcano, Cecilia; Murphy, George F.; Liu, Chen; Sadelain, Michel; Sauer, Martin G.; Sant'Angelo, Derek; van den Brink, Marcel R. M.

Age-Associated Changes in the Differentiation Potentials of Human Circulating Hematopoietic Progenitors to T- or NK-Lineage Cells

JOURNAL OF IMMUNOLOGY

IF3.4

2013-06-15

OAAI

Kyoizumi, Seishi; Kubo, Yoshiko; Kajimura, Junko; Yoshida, Kengo; Imai, Kazue; Hayashi, Tomonori; Nakachi, Kei; Young, Lauren F.; Moore, Malcolm A.; van den Brink, Marcel R. M.; Kusunoki, Yoichiro

Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity 过继转移的TRAIL T细胞抑制GVHD并增强抗肿瘤活性

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2013-05-15

OAAI

Ghosh, Arnab; Dogan, Yildirim; Moroz, Maxim; Holland, Amanda M.; Yim, Nury L.; Rao, Uttam K.; Young, Lauren F.; Tannenbaum, Daniel; Masih, Durva; Velardi, Enrico; Tsai, Jennifer J.; Jenq, Robert R.; Penack, Olaf; Hanash, Alan M.; Smith, Odette M.; Piersanti, Kelly; Lezcano, Cecilia; Murphy, George F.; Liu, Chen; Palomba, M. Lia; Sauer, Martin G.; Sadelain, Michel; Ponomarev, Vladimir; van den Brink, Marcel R. M.

Nrf2 regulates haematopoietic stem cell function Nrf2调控造血干细胞功能

NATURE CELL BIOLOGY

IF19.1

2013-02-24

191

OAAI

Tsai, Jennifer J.; Dudakov, Jarrod A.; Takahashi, Koichi; Shieh, Jae-Hung; Velardi, Enrico; Holland, Amanda M.; Singer, Natalie V.; West, Mallory L.; Smith, Odette M.; Young, Lauren F.; Shono, Yusuke; Ghosh, Arnab; Hanash, Alan M.; Tran, Hien T.; Moore, Malcolm A. S.; van den Brink, Marcel R. M.

Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease Interleukin-22保护肠道干细胞免受免疫介导的组织损伤并调节对移植物抗宿主病的敏感性

IMMUNITY

IF26.3

2012-08-01

527

OAAI

Hanash, Alan M.; Dudakov, Jarrod A.; Hua, Guoqiang; O'Connor, Margaret H.; Young, Lauren F.; Singer, Natalie V.; West, Mallory L.; Jenq, Robert R.; Holland, Amanda M.; Kappel, Lucy W.; Ghosh, Arnab; Tsai, Jennifer J.; Rao, Uttam K.; Yim, Nury L.; Smith, Odette M.; Velardi, Enrico; Hawryluk, Elena B.; Murphy, George F.; Liu, Chen; Fouser, Lynette A.; Kolesnick, Richard; Blazar, Bruce R.; van den Brink, Marcel R. M.

Regulation of intestinal inflammation by microbiota following allogeneic bone marrow transplantation 微生物群对异基因骨髓移植后肠道炎症的调控

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2012-04-30

543

OAAI

Jenq, Robert R.; Ubeda, Carles; Taur, Ying; Menezes, Clarissa C.; Khanin, Raya; Dudakov, Jarrod A.; Liu, Chen; West, Mallory L.; Singer, Natalie V.; Equinda, Michele J.; Gobourne, Asia; Lipuma, Lauren; Young, Lauren F.; Smith, Odette M.; Ghosh, Arnab; Hanash, Alan M.; Goldberg, Jenna D.; Aoyama, Kazutoshi; Blazar, Bruce R.; Pamer, Eric G.; van den Brink, Marcel R. M.

Genetically engineered allogeneic T Cells for BMT immunotherapy: Expression of TRAIL and PLZF selectively enhances GVT and abrogates GVHD

CANCER RESEARCH

IF16.6

2011-04-01

PREAI

Ghosh, Arnab; Holland, Amanda M.; Dogan, Yildirim; Yim, Nury; Rao, Uttam K.; Young, Lauren F.; Smith, Odette M.; Jenq, Robert; Na, Il-Kang; Tsai, Jennifer J.; Singer, Natalie; West, Mallory; Penack, Olaf; Hanash, Alan M.; Sant'Angelo, Derek; Sadelain, Michel; van den Brinks, Marcel R. M.

研究方向