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Nerve growth factor precursor alterations in neuron-derived extracellular vesicles from individuals with Down syndrome along the Alzheimer's disease continuum 唐氏综合征个体中，源自神经元的外泌体中神经生长因子前体改变，沿着阿尔茨海默病连续谱。 Valle-Tamayo, N; Aranha, MR; Pérez-González, R; Serrano-Requena, S; Videla, L; Barroeta, I; Benejam, B; Chiva-Blanch, G; Jimenez, A; Busciglio, J; Wisniewski, T; Do Carmo, S; Alvarez-Sánchez, E; Muñoz, L; Bejanin, A; Belbin, O; Alcolea, D; Carmona-Iragui, M; Lleó, A; Cuello, AC; Fortea, J; Dols-Icardo, O; Iulita, MF 分享 收藏
Imagine, Discover, Inspire: Proceedings of the 4th International Conference of the Trisomy 21 Research Society 想象，发现，启发: 21三体研究学会第四届国际会议论文集 Flores-Aguilar, Lisi; Hamlett, Eric D.; Araya, Paula; Barone, Eugenio; Bhattacharyya, Anita; Carmona-Iragui, Maria; Chan, Li; Christian, Brad; Costa, Alberto C. S.; Costanzo, Floriana; Del Hoyo Soriano, Laura; Dierssen, Mara; Eichler, Evan E.; Fisher, Elizabeth; Galbraith, Matthew; Ghosh, Sujay; Gimenez, Sandra; Guedj, Faycal; Guidi, Sandra; Iulita, Maria Florencia; Mobley, William; Pelleri, Maria Chiara; Potier, Marie-Claude; Rabin, Karen R.; Rachubinski, Angela; Rebillat, Anne-Sophie; Rubenstein, Eric; Saternos, Hannah; Sordo, Lorena; Strydom, Andre; Valle-Tamayo, Natalia; Waugh, Katherine A.; Yu, Eugene; Zeldich, Ella; Busciglio, Jorge; Head, Elizabeth 分享 收藏
Basal forebrain atrophy along the Alzheimer's disease continuum in adults with Down syndrome 唐氏综合症成人沿阿尔茨海默氏病连续体的基底前脑萎缩 Rozalem Aranha, Mateus; Iulita, Maria Florencia; Montal, Victor; Pegueroles, Jordi; Bejanin, Alexandre; Vaque-Alcazar, Lidia; Grothe, Michel J.; Carmona-Iragui, Maria; Videla, Laura; Benejam, Bessy; Arranz, Javier; Padilla, Concepcion; Valldeneu, Silvia; Barroeta, Isabel; Altuna, Miren; Fernandez, Susana; Ribas, Laia; Valle-Tamayo, Natalia; Alcolea, Daniel; Gonzalez-Ortiz, Sofia; Bargallo, Nuria; Zetterberg, Henrik; Blennow, Kaj; Blesa, Rafael; Wisniewski, Thomas; Busciglio, Jorge; Cuello, A. Claudio; Lleo, Alberto; Fortea, Juan 分享 收藏
Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission Yeo, Michele; Chen, Yong; Jiang, Changyu; Chen, Gang; Wang, Kaiyuan; Chandra, Sharat; Bortsov, Andrey; Lioudyno, Maria; Zeng, Qian; Wang, Peng; Wang, Zilong; Busciglio, Jorge; Ji, Ru-Rong; Liedtke, Wolfgang 分享 收藏
Evolution of neuroinflammation across the lifespan of individuals with Down syndrome Flores-Aguilar, Lisi; Florencia Iulita, M.; Kovecses, Olivia; Torres, Maria D.; Levi, Sarah M.; Zhang, Yian; Askenazi, Manor; Wisniewski, Thomas; Busciglio, Jorge; Cuello, A. Claudio 分享 收藏
Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells Hwang, Sunyoung; Williams, Jessica F.; Kneissig, Maja; Lioudyno, Maria; Rivera, Isabel; Helguera, Pablo; Busciglio, Jorge; Storchova, Zuzana; King, Megan C.; Torres, Eduardo M. 分享 收藏
Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells Nrf2稳定可防止唐氏综合症细胞的关键氧化损伤 Zamponi, Emiliano; Zamponi, Nahuel; Coskun, Pinar; Quassollo, Gonzalo; Lorenzo, Alfredo; Cannas, Sergio A.; Pigino, Gustavo; Chialvo, Dante R.; Gardiner, Katheleen; Busciglio, Jorge; Helguera, Pablo 分享 收藏
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Metabolic and Growth Rate Alterations in Lymphoblastic Cell Lines Discriminate Between Down Syndrome and Alzheimer's Disease Coskun, Pinar; Helguera, Pablo; Nemati, Zahra; Bohannan, Ryan C.; Thomas, Jean; Schriner, Samuel E.; Argueta, Jocelyn; Doran, Eric; Wallace, Douglas C.; Lott, Ira T.; Busciglio, Jorge 分享 收藏
DYRK1A as a biomarker and a therapeutic target for cognitive deficits in Down syndrome and Alzheimer's disease Delabar, J. M.; Janel, N.; Badel, A.; Paul, J.; Rebillat, A. S.; Coskun, P.; Busciglio, J.; Lott, I.; Schubert, M.; Sarazin, M.; Alexopoulos, P. 分享 收藏
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes Peiris, Heshan; Duffield, Michael D.; Fadista, Joao; Jessup, Claire F.; Kashmir, Vinder; Genders, Amanda J.; Mcgee, Sean L.; Martin, Alyce M.; Saiedi, Madiha; Morton, Nicholas; Carter, Roderick; Cousin, Michael A.; Kokotos, Alexandros C.; Oskolkov, Nikolay; Volkov, Petr; Hough, Tertius A.; Fisher, Elizabeth M. C.; Tybulewicz, Victor L. J.; Busciglio, Jorge; Coskun, Pinar E.; Becker, Ann; Belichenko, Pavel V.; Mobley, William C.; Ryan, Michael T.; Chan, Jeng Yie; Laybutt, D. Ross; Coates, P. Toby; Yang, Sijun; Ling, Charlotte; Groop, Leif; Pritchard, Melanie A.; Keating, Damien J. 分享 收藏
Nerve growth factor metabolic dysfunction in Down's syndrome brains Iulita, M. Florencia; Do Carmo, Sonia; Ower, Alison K.; Fortress, Ashley M.; Aguilar, Lisi Flores; Hanna, Michael; Wisniewski, Thomas; Granholm, Ann-Charlotte; Buhusi, Mona; Busciglio, Jorge; Cuello, A. Claudio 分享 收藏
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Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter Yeo, Michele; Berglund, Ken; Hanna, Michael; Guo, Junjie U.; Kittur, Jaya; Torres, Maria D.; Abramowitz, Joel; Busciglio, Jorge; Gao, Yuan; Birnbaumer, Lutz; Liedtke, Wolfgang B. 分享 收藏
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