Michael D. Aleo - Publications, H-index & Citations

Michael D. Aleo

pfizer usa

26H指数

60论文数

2.7K被引数

收录论文 19

发表时间

AI/ML Models to Predict the Severity of Drug-Induced Liver Injury for Small Molecules

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2023-06-09

PREAI

Rao, Mohan; Nassiri, Vahid; Alhambra, Cristobal; Snoeys, Jan; Van Goethem, Freddy; Irrechukwu, Onyi; Aleo, Michael D.; Geys, Helena; Mitra, Kaushik; Will, Yvonne

Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury via mitochondrial or other mechanisms

ACTA PHARMACEUTICA SINICA B

IF14.6

2021-12-01

OAAI

Rana, Payal; Aleo, Michael D.; Wen, Xuerong; Kogut, Stephen

An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury

ARCHIVES OF TOXICOLOGY

IF6.9

2020-08-20

PREAI

Oda, Shingo; Uchida, Yuka; Aleo, Michael D.; Koza-Taylor, Petra H.; Matsui, Yusuke; Hizue, Masanori; Marroquin, Lisa D.; Whritenour, Jessica; Uchida, Eri; Yokoi, Tsuyoshi

Most Influential Physicochemical and In Vitro Assay Descriptors for Hepatotoxicity and Nephrotoxicity Prediction

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2020-04-27

PREAI

Rana, Payal; Kogut, Stephen; Wen, Xuerong; Akhlaghi, Fatemeh; Aleo, Michael D.

A Novel Lipidomics-Based Approach to Evaluating the Risk of Clinical Hepatotoxicity Potential of Drugs in 3D Human Microtissues

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2019-12-10

PREAI

Goracci, Laura; Valeri, Aurora; Sciabola, Simone; Aleo, Michael D.; Moritz, Wolfgang; Lichtenberg, Jan; Cruciani, Gabriele

Moving beyond Binary Predictions of Human Drug-Induced Liver Injury (DILI) toward Contrasting Relative Risk Potential

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2019-09-18

PREAI

Aleo, Michael D.; Shah, Falgun; Allen, Scott; Barton, Hugh A.; Costales, Chester; Lazzaro, Sarah; Leung, Louis; Nilson, Andrea; Obach, R. Scott; Rodrigues, A. David; Will, Yvonne

Evaluation of in Vitro Mitochondrial Toxicity Assays and Physicochemical Properties for Prediction of Organ Toxicity Using 228 Pharmaceutical Drugs

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2018-12-10

PREAI

Rana, Payal; Aleo, Michael D.; Gosink, Mark; Will, Yvonne

Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals (vol 30, pg 1219, 2017)

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2017-05-18

OAAI

Aleo, Michael D.; Shah, Falgun; He, Kan; Bonin, Paul D.; Rodrigues, A. David

Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2017-05-04

PREAI

Aleo, Michael D.; Shah, Falgun; He, Kan; Bonin, Paul D.; Rodrigues, A. David

Inhibition of Hepatobiliary Transport Activity by the Antibacterial Agent Fusidic Acid: Insights into Factors Contributing to Conjugated Hyperbilirubinemia/Cholestasis

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2016-10-04

PREAI

Lapham, Kimberly; Novak, Jonathan; Marroquin, Lisa D.; Swiss, Rachel; Qin, Shuzhen; Strock, Christopher J.; Scialis, Renato; Aleo, Michael D.; Schroeter, Thomas; Eng, Heather; Rodrigues, A. David; Kalgutkar, Amit S.

Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic in vitro Assays

TOXICOLOGICAL SCIENCES

IF4.1

2015-07-23

116

OAAI

Shah, Falgun; Leung, Louis; Barton, Hugh A.; Will, Yvonne; Rodrigues, A. David; Greene, Nigel; Aleo, Michael D.

Human Drug-Induced Liver Injury Severity Is Highly Associated With Dual Inhibition of Liver Mitochondrial Function and Bile Salt Export Pump

HEPATOLOGY

IF15.8

2014-09-01

185