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F

Francis X. Wilson

University of Oxford
H指数:29
被引数:2,637

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Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy

4，6-二苯基嘧啶-2-碳酰肼作为促性腺激素调节剂治疗杜氏肌营养不良的发现和作用机制研究

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
2021-08-019
PREAI
Vuorinen, Aini; Wilkinson, Isabel V. L.; Chatzopoulou, Maria; Edwards, Ben; Squire, Sarah E.; Fairclough, Rebecca J.; Bazan, Noelia Araujo; Milner, Josh A.; Conole, Daniel; Donald, James R.; Shah, Nandini; Willis, Nicky J.; Martinez, R. Fernando; Wilson, Francis X.; Wynne, Graham M.; Davies, Stephen G.; Davies, Kay E.; Russell, Angela J.
2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2020-06-1816
PREAI
Babbs, Arran; Berg, Adam; Chatzopoulou, Maria; Davies, Kay E.; Davies, Stephen G.; Edwards, Benjamin; Elsey, David J.; Emer, Enrico; Guiraud, Simon; Harriman, Shawn; Lecci, Cristina; Moir, Lee; Peters, David; Robinson, Neil; Rowley, Jessica A.; Russell, Angela J.; Squire, Sarah E.; Tinsley, Jonathon M.; Wilson, Francis X.; Wynne, Graham M.
Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2019-10-1010
OAAI
Chatzopoulou, Maria; Claridge, Tim D. W.; Davies, Kay E.; Davies, Stephen G.; Elsey, David J.; Emer, Enrico; Fletcher, Ai M.; Harriman, Shawn; Robinson, Neil; Rowley, Jessica A.; Russell, Angela J.; Tinsley, Jonathon M.; Weaver, Richard; Wilkinson, Isabel V. L.; Willis, Nicky J.; Wilson, Francis X.; Wynne, Graham M.
C-Branched Iminosugars: α-Glucosidase Inhibition by Enantiomers of isoDMDP, isoDGDP, and isoDAB-L-isoDMDP Compared to Miglitol and Miglustat
JOURNAL OF ORGANIC CHEMISTRY
IF3.6
2013-06-0549
PRE
Jenkinson, Sarah F.; Best, Daniel; Saville, A. Waldo; Mui, James; Martinez, R. Fernando; Nakagawa, Shinpei; Kunimatsu, Takahito; Alonzi, Dominic S.; Butters, Terry D.; Norez, Caroline; Becq, Frederic; Bleriot, Yves; Wilson, Francis X.; Weymouth-Wilson, Alexander C.; Kato, Atsushi; Fleet, George W. J.
Discovery of 2-Arylbenzoxazoles as Upregulators of Utrophin Production for the Treatment of Duchenne Muscular Dystrophy
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2011-04-1572
PREAI
Chancellor, Daniel R.; Davies, Kay E.; De Moor, Olivier; Dorgan, Colin R.; Johnson, Peter D.; Lambert, Adam G.; Lawrence, Daniel; Lecci, Cristina; Maillol, Carole; Middleton, Penny J.; Nugent, Gary; Poignant, Severine D.; Potter, Allyson C.; Price, Paul D.; Pye, Richard J.; Storer, Richard; Tinsley, Jonathon M.; van Well, Renate; Vickers, Richard; Vile, Julia; Wilkes, Fraser J.; Wilson, Francis X.; Wren, Stephen P.; Wynne, Graham M.

研究方向

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G
Graham M. Wynne
H 指数:20论文数:78被引数:1,255
K
Kay E. Davies
H 指数:90论文数:511被引数:3.3万
A
Atsushi Kato
H 指数:52论文数:411被引数:9,897
A
Angela J. Russell
H 指数:46论文数:348被引数:5,960
G
George W. J. Fleet
H 指数:64论文数:762被引数:1.7万
S
Stephen G. Davies
H 指数:61论文数:1,335被引数:1.9万
M
Maria Chatzopoulou
H 指数:18论文数:50被引数:1,003
S
Sarah Squire
H 指数:26论文数:112被引数:2,460
S
Shinpei Nakagawa
H 指数:19论文数:61被引数:785
胡祥国 封面图
胡祥国
H 指数:23论文数:92被引数:1,763