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Stephen G. Davies

university of oxford

61H指数
1.3K论文数
1.9W被引数
收录论文 100
发表时间
Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia
err2024-01-01
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errOAAI
errCogswell, Thomas J.; Josa-Cullere, Laia; Zimmer, David; Galan, Sebastien R. G.; Jay-Smith, Morgan; Harris, Kate S.; Bataille, Carole J. R.; Jackson, Thomas R.; Zhang, Douzi; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Wynne, Graham M.; Russell, Angela J.
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Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines
err2023-10-01
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PREAI
errJosa-Cullere, Laia; Galan, Sebastien R. G.; Cogswell, Thomas J.; Jackson, Thomas R.; Jay-Smith, Morgan; Mola, Laura; Greaves, Christopher R.; Carter, Tom S.; Madden, Katrina S.; Trott, Sophie; Zhang, Douzi; Bataille, Carole J. R.; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Naylor, Alan; Wynne, Graham M.; Russell, Angela J.
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General Approach to Enantiopure 1-Aminopyrrolizidines: Application to the Asymmetric Synthesis of the Loline Alkaloids
err2023-06-13
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errOAAI
errDavies, Stephen G.; Fletcher, Ai M.; Linsdall, Sean M.; Roberts, Paul M.; Thomson, James E.
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Evaluating the efficacy and safety of a novel prophylactic nasal spray in the prevention of SARS-CoV-2 infection: A multi-centre, double blind, placebo-controlled, randomised trial.
err2022-10-01
err10
errOAAI
errBalmforth, Damian; Swales, James A.; Silpa, Laurence; Dunton, Alan; Davies, Kay E.; Davies, Stephen G.; Kamath, Archana; Gupta, Jayanti; Gupta, Sandeep; Masood, M. Abid; McKnight, Aine; Rees, Doug; Russell, Angela J.; Jaggi, Manu; Uppal, Rakesh
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Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy
err2022-09-01
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errOAAI
errChatzopoulou, Maria; Conole, Daniel; Emer, Enrico; Rowley, Jessica A.; Willis, Nicky J.; Squire, Sarah E.; Gill, Becky; Brough, Steve; Wilson, Francis X.; Wynne, Graham M.; Davies, Stephen G.; Davies, Kay E.; Russell, Angela J.
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Microgrewiapine C: Asymmetric Synthesis, Spectroscopic Data, and Configuration Assignment
err2022-06-30
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errOAAI
errDavies, Stephen G.; Fletcher, Ai M.; Roberts, Paul M.; Taylor, Cameron E.; Thomson, James E.
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Synthesis and Configuration of O-Acetyl Microgrewiapine A: Phantomization of O-Acetyl 6-epi-Microgrewiapine A
err2021-12-17
err4
PREAI
errDavies, Stephen G.; Fletcher, Ai M.; Roberts, Paul M.; Taylor, Cameron E.; Thomson, James E.
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Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro
err2021-11-02
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errOAAI
errJosa-Cullere, Laia; Cogswell, Thomas J.; Georgiou, Irene; Jay-Smith, Morgan; Jackson, Thomas R.; Bataille, Carole J. R.; Davies, Stephen G.; Vyas, Paresh; Milne, Thomas A.; Wynne, Graham M.; Russell, Angela J.
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A Phenotypic Screen Identifies a Compound Series That Induces Differentiation of Acute Myeloid Leukemia Cells In Vitro and Shows Antitumor Effects In Vivo
err2021-10-21
err6
errOAAI
errJosa-Cullere, Laia; Madden, Katrina S.; Cogswell, Thomas J.; Jackson, Thomas R.; Carter, Tom S.; Zhang, Douzi; Trevitt, Graham; Davies, Stephen G.; Vyas, Paresh; Wynne, Graham M.; Milne, Thomas A.; Russell, Angela J.
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Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy4,6-二苯基嘧啶-2-碳酰肼作为促性腺激素调节剂治疗杜氏肌营养不良的发现和作用机制研究
err2021-08-01
err9
PREAI
errVuorinen, Aini; Wilkinson, Isabel V. L.; Chatzopoulou, Maria; Edwards, Ben; Squire, Sarah E.; Fairclough, Rebecca J.; Bazan, Noelia Araujo; Milner, Josh A.; Conole, Daniel; Donald, James R.; Shah, Nandini; Willis, Nicky J.; Martinez, R. Fernando; Wilson, Francis X.; Wynne, Graham M.; Davies, Stephen G.; Davies, Kay E.; Russell, Angela J.
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Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators
err2020-11-04
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errOAAI
errChatzopoulou, Maria; Emer, Enrico; Lecci, Cristina; Rowley, Jessica A.; Casagrande, Anne-Sophie; Moir, Lee; Squire, Sarah E.; Davies, Stephen G.; Harriman, Shawn; Wynne, Graham M.; Wilson, Francis X.; Davies, Kay E.; Russell, Angela J.
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Aminothiazolones as potent, selective and cell active inhibitors of the PIM kinase family
err2020-11-01
err1
PREAI
errQuevedo, Camilo E.; Bataille, Carole J. R.; Byrne, Simon; Durbin, Matthew; Elkins, Jon; Guillermo, Abigail; Jones, Alan M.; Knapp, Stefan; Nadali, Anna; Walker, Roderick G.; Wilkinson, Isabel V. L.; Wynne, Graham M.; Davies, Stephen G.; Russell, Angela J.
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2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy
err2020-06-18
err16
PREAI
errBabbs, Arran; Berg, Adam; Chatzopoulou, Maria; Davies, Kay E.; Davies, Stephen G.; Edwards, Benjamin; Elsey, David J.; Emer, Enrico; Guiraud, Simon; Harriman, Shawn; Lecci, Cristina; Moir, Lee; Peters, David; Robinson, Neil; Rowley, Jessica A.; Russell, Angela J.; Squire, Sarah E.; Tinsley, Jonathon M.; Wilson, Francis X.; Wynne, Graham M.
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Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid
err2020-01-03
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errOAAI
errWilkinson, Isabel V. L.; Perkins, Kelly J.; Dugdale, Hannah; Moir, Lee; Vuorinen, Aini; Chatzopoulou, Maria; Squire, Sarah E.; Monecke, Sebastian; Lomow, Alexander; Geese, Marcus; Charles, Philip D.; Burch, Peter; Tinsley, Jonathan M.; Wynne, Graham M.; Davies, Stephen G.; Wilson, Francis X.; Rastinejad, Fraydoon; Mohammed, Shabaz; Davies, Kay E.; Russell, Angela J.
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Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid
err2019-10-10
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errOAAI
errChatzopoulou, Maria; Claridge, Tim D. W.; Davies, Kay E.; Davies, Stephen G.; Elsey, David J.; Emer, Enrico; Fletcher, Ai M.; Harriman, Shawn; Robinson, Neil; Rowley, Jessica A.; Russell, Angela J.; Tinsley, Jonathon M.; Weaver, Richard; Wilkinson, Isabel V. L.; Willis, Nicky J.; Wilson, Francis X.; Wynne, Graham M.
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Synthesis of (-)-Conduramine A1, (-)-Conduramine A2 and (-)-Conduramine E2 in Six Steps from Cyclohexa-1,4-diene
err2019-09-13
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errOAAI
errPinto, Solange Da Silva; Davies, Stephen G.; Fletcher, Ai M.; Roberts, Paul M.; Thomson, James E.
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N-Acetylcolchinol Methyl Ether (a Natural Product); Suhailamine (a Phantom Natural Product)
err2019-09-05
err8
PREAI
errDavies, Stephen G.; Fletcher, Ai M.; Roberts, Paul M.; Thomson, James E.; Yeung, Angus
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The Hancock Alkaloids (-)-Cuspareine, (-)-Galipinine, (-)-Galipeine, and (-)-Angustureine: Asymmetric Syntheses and Corrected 1H and 13C NMR Data
err2018-11-20
err29
PREAI
errDavies, Stephen G.; Fletcher, Ai M.; Houlsby, Ian T. T.; Roberts, Paul M.; Thomson, James E.; Zimmer, David
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