Natalia J. Martinez - Publications, H-index & Citations

Natalia J. Martinez

University of Talca

27H指数

120论文数

3.2K被引数

收录论文 38

发表时间

Thermal treatment and solvent extraction modulate the antiglycation and proteasome protection activities of Ribes magellanicum phenolics 热处理和溶剂提取调节Ribes magellanicum酚类化合物的抗糖基化及蛋白酶体保护活性

Food Bioscience

IF5.9

2026-03-18

PREAI

Felipe Ávila; Nicolás Mora; Natalia Martinez; Felipe Jiménez-Aspee; Francisco Armijo; Stefano Migliorelli; Alejandra San Martin; Bertrand Friguet

A Machine Learning Based Analysis Method for Small Molecule High Content Screening of 3D Cancer Spheroid Morphology 基于机器学习的3D癌细胞球形态小分子高内涵筛选分析方法

Molecular Pharmacology

IF3

2025-08-05

OAAI

Vishakha Goyal; Dvir Blivis; Steven A. Titus; Misha Itkin; Alexey Zakharov; Kelli Wilson; Natalia J. Martinez; Ty C. Voss

Discovery of SARS-CoV-2 Nsp14-Methyltransferase (MTase) Inhibitors by Harnessing Scaffold-Centric Exploration of the Ultra Large Chemical Space 通过利用骨架中心探索超大规模化学空间发现SARS-CoV-2 Nsp14-甲基转移酶(MTase)抑制剂

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE

IF3.7

2025-04-25

PREAI

Pal, S; Hanson, QM; Ogden, SC; Lee, EM; Martinez, NJ; Zakharov, AV

Effect of Thermal Treatment on the Extraction and Antioxidant and Antiglycation Activities of (Poly)phenols from Ribes magellanicum

MOLECULES

IF4.6

2025-01-15

OAAI

Avila, Felipe; Martinez, Natalia; Mora, Nicolas; Marquez, Katherine; Jimenez-Aspee, Felipe

Developing a drug repurposing screen for head and neck squamous cell carcinoma using a novel c-Rel bioassay

CANCER RESEARCH

IF16.6

2024-03-22

PREAI

Altwegg, Kristin Ann; King, Kathryn E.; Blivis, Dvir; Voss, Ty C.; Martinez, Natalia J.; Weinberg, Wendy C.; Henderson, Mark J.

Effect of Thermal Treatment of Ribes magellanicum on the Extraction of Polyphenols, Advanced Glycation End Products Inhibition, Gastrointestinal Digestion and Cytoprotection of AGS Cells

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2023-11-01

PREAI

Avila, Felipe; Martinez, Natalia; Jimenez-Aspee, Felipe; Mora, Nicolas; Schmeda-Hirschmann, Guillermo

Real-world discontinuations due to neuropsychiatric symptoms in people living with HIV treated with second-generation integrase inhibitors: a systematic review

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY

IF3.8

2023-04-20

OAAI

Perez-Valero, Ignacio; Corona, Diana; Martinez, Natalia; Lopez-Cavanillas, Maria; Lluis, Carla; Luque, Isabel

PKD phosphorylation and COP9/Signalosome modulate intracellular Spry2 protein stability PKD磷酸化和COP9/信号小体调节细胞内Spry2蛋白稳定性

ONCOGENESIS

IF6.4

2023-04-12

OAAI

Martinez, Natalia; Gragera, Teresa; de Lucas, Maria Pilar; Camara, Ana Belen; Ballester, Alicia; Anta, Berta; Fernandez-Medarde, Alberto; Lopez-Briones, Tania; Ortega, Judith; Pena-Jimenez, Daniel; Barbachano, Antonio; Montero-Calle, Ana; Cordero, Victor; Barderas, Rodrigo; Iglesias, Teresa; Yunta, Monica; Oliva, Jose Luis; Munoz, Alberto; Santos, Eugenio; Zarich, Natasha; Rojas-Cabaneros, Jose M.

A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells (vol 10, 4203, 2020)

SCIENTIFIC REPORTS

IF3.9

2022-10-13

OAAI

Asawa, Rosita R.; Danchik, Carina; Zakharov, Alexey; Chen, Yuchi; Voss, Ty; Jadhav, Ajit; Wallace, Darren P.; Trott, Josephine F.; Weiss, Robert H.; Simeonov, Anton; Martinez, Natalia J.

Integrating In Vitro and In Silico Analysis of a Cationic Antimicrobial Peptide Interaction with Model Membranes of Colistin-Resistant Pseudomonas aeruginosa Strains

PHARMACEUTICS

IF5.5

2022-06-12

OAAI

Rivera-Sanchez, Sandra Patricia; Ocampo-Ibanez, Ivan Dario; Liscano, Yamil; Martinez, Natalia; Munoz, Isamar; Manrique-Moreno, Marcela; Martinez-Martinez, Luis; Onate-Garzon, Jose

Discovery and Optimization of 2H-1λ2-Pyridin-2-one Inhibitors of Mutant Isocitrate Dehydrogenase 1 for the Treatment of Cancer

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-04-06

OAAI

Rohde, Jason M.; Karavadhi, Surendra; Pragani, Rajan; Liu, Li; Fang, Yuhong; Zhang, Weihe; McIver, Andrew; Zheng, Hongchao; Liu, Qingyang; Davis, Mindy, I; Urban, Daniel J.; Lee, Tobie D.; Cheff, Dorian M.; Hollingshead, Melinda; Henderson, Mark J.; Martinez, Natalia J.; Brimacombe, Kyle R.; Yasgar, Adam; Zhao, Wei; Klumpp-Thomas, Carleen; Michael, Sam; Covey, Joseph; Moore, William J.; Stott, Gordon M.; Li, Zhuyin; Simeonov, Anton; Jadhav, Ajit; Frye, Stephen; Hall, Matthew D.; Shen, Min; Wang, Xiaodong; Patnaik, Samarjit; Boxer, Matthew B.

Critical Assessment of Artificial Intelligence Methods for Prediction of hERG Channel Inhibition in the Big Data Era 大数据时代hERG通道抑制预测人工智能方法的批判性评估

JOURNAL OF CHEMICAL INFORMATION AND MODELING

IF5.3

2020-12-01

OAAI

Siramshetty, Vishal B.; Dac-Trung Nguyen; Martinez, Natalia J.; Southall, Noel T.; Simeonov, Anton; Zakharov, Alexey, V

Roles for the cancer stem cell marker Aldh1A1 in Merlin null nervous system tumors

CANCER RESEARCH

IF16.6

2020-08-15

PREAI

Hillson, Lily; Laraba, Liyam; Shivane, Aditya G.; Edwards, Philip; Bantukallu, Ganesha; Simeonov, Anton; Martinez, Natalia J.; Yang, Shyh-Ming; Parkinson, David B.

Identification of a G-Protein-Independent Activator of GIRK Channels

CELL REPORTS

IF6.9

2020-06-01

OAAI

Zhao, Yulin; Ung, Peter Man-Un; Zahoranszky-Kohalmi, Gergely; Zakharov, Alexey, V; Martinez, Natalia J.; Simeonov, Anton; Glaaser, Ian W.; Rai, Ganesha; Schlessinger, Avner; Marugan, Juan J.; Slesinger, Paul A.

A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells

SCIENTIFIC REPORTS

IF3.9

2020-03-06

OAAI

Asawa, Rosita R.; Danchik, Carina; Zahkarov, Alexey; Chen, Yuchi; Voss, Ty; Jadhav, Ajit; Wallace, Darren P.; Trott, Josephine F.; Weiss, Robert H.; Simeonov, Anton; Martinez, Natalia J.

Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models 溶酶体TRP通道的小分子激活可改善小鼠模型中的杜氏肌营养不良症

SCIENCE ADVANCES

IF12.5

2020-02-07

OAAI

Yu, Lu; Zhang, Xiaoli; Yang, Yexin; Li, Dan; Tang, Kaiyuan; Zhao, Zifan; He, Wanwan; Wang, Ce; Sahoo, Nirakar; Converso-Baran, Kimber; Davis, Carol S.; Brooks, Susan, V; Bigot, Anne; Calvo, Raul; Martinez, Natalia J.; Southall, Noel; Hu, Xin; Marugan, Juan; Ferrer, Marc; Xu, Haoxing

RETRACTION: hSos1 contains a new amino-terminal regulatory motif with specific binding affinity for its pleckstrin homology domain (Retraction of Vol 277, Pg 44171, 2002)

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-07-01

OAAI

Jorge, Rocio; Zarich, Natasha; Oliva, Jose Luis; Azanedo, Marta; Martinez, Natalia; de la Cruz, Xavier; Rojas, Jose M.

A widely-applicable high-throughput cellular thermal shift assay (CETSA) using split Nano Luciferase

SCIENTIFIC REPORTS

IF3.9

2018-06-21

OAAI

Martinez, Natalia J.; Asawa, Rosita R.; Cyr, Matthew G.; Zakharov, Alexey; Urban, Daniel J.; Roth, Jacob S.; Wallgren, Eric; Klumpp-Thomas, Carleen; Coussens, Nathan P.; Rai, Ganesha; Yang, Shyh-Ming; Hall, Matthew D.; Marugan, Juan J.; Simeonov, Anton; Henderson, Mark J.

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-05-16

OAAI

Yang, Shyh-Ming; Martinez, Natalia J.; Yasgar, Adam; Danchik, Carina; Johansson, Catrine; Wang, Yuhong; Baljinnyam, Bolormaa; Wang, Amy Q.; Xu, Xin; Shah, Pranav; Chef, Dorian; Wang, Xinran S.; Roth, Jacob; Lal-Nag, Madhu; Dunford, James E.; Oppermann, Udo; Vasiliou, Vasilis; Simeonov, Anton; Jadhav, Ajit; Maloney, David J.

Assessing inhibitors of mutant isocitrate dehydrogenase using a suite of pre-clinical discovery assays

SCIENTIFIC REPORTS

IF3.9

2017-10-06

OAAI

Urban, Daniel J.; Martinez, Natalia J.; Davis, Mindy I.; Brimacombe, Kyle R.; Cheff, Dorian M.; Lee, Tobie D.; Henderson, Mark J.; Titus, Steven A.; Pragani, Rajan; Rohde, Jason M.; Liu, Li; Fang, Yuhong; Karavadhi, Surendra; Shah, Pranav; Lee, Olivia W.; Wang, Amy; McIver, Andrew; Zheng, Hongchao; Wang, Xiaodong; Xu, Xin; Jadhav, Ajit; Simeonov, Anton; Shen, Min; Boxer, Matthew B.; Hall, Matthew D.

研究方向