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Yuquan Tong

State University System of Florida

14H指数
29论文数
1.6K被引数
收录论文 20
发表时间
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Unbiased RNA Degrader Identification Uncovers an LC3B-Recruiting Chimera for COL15A1 mRNA Degradation无偏RNA降解剂鉴定发现一种招募LC3B的嵌合体用于COL15A1 mRNA降解
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2025-11-01
err0
PREAI
errSu, Xiaoxuan; Tong, Yuquan; Zanon, Patrick R. A.; Wang, Jielei; Tanaka, Toru; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Design of an Orally Bioavailable Small Molecule That Modulates the Microtubule-Associated Protein Tau’s Pre-mRNA Splicing一种可口服生物利用的小分子设计，该分子能够调节微管相关蛋白Tau的pre-mRNA剪接
errACS Chemical Biology
IF3.8
err2025-06-23
err0
errOAAI
errPeiyuan Zhang; Amirhossein Taghavi; Masahito Abe; Haruo Aikawa; Yoshihiro Akahori; Jonathan L. Chen; Yuquan Tong; Jared T. Baisden; Michael D. Cameron; Jessica L. Childs-Disney; Matthew D. Disney
err分享
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Editorial: Recent advancements in RNA-based and targeted therapeutics编者按：RNA基和靶向疗法方面的最新进展
errFRONTIERS IN GENETICS
IF2.8
err2025-04-08
err0
errOAAI
errMeng, Yiming; Serio, Viola Bianca; Tong, Yuquan; Huang, Tao; Palmieri, Maria
err分享
err收藏
Targeting RNA with small molecules, from RNA structures to precision medicines: IUPHAR review: 40用小分子靶向RNA，从RNA结构到精密药物: IUPHAR综述: 40
errBRITISH JOURNAL OF PHARMACOLOGY
IF7.7
err2024-09-03
err1
PREAI
errTong, Yuquan; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Transcriptome-Wide, Unbiased Profiling of Ribonuclease Targeting Chimeras
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2024-07-24
err0
PREAI
errTong, Yuquan; Su, Xiaoxuan; Rouse, Warren; Childs-Disney, Jessica L.; Taghavi, Amirhossein; Zanon, Patrick R. A.; Kovachka, Sandra; Wang, Tenghui; Moss, Walter N.; Disney, Matthew D.
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Heterobifunctional small molecules to modulate RNA function
errTRENDS IN PHARMACOLOGICAL SCIENCES
IF19.9
err2024-05-01
err2
PREAI
errKovachka, Sandra; Tong, Yuquan; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease- targeting chimera通过靶向核糖核酸酶的嵌合体靶向其结构化mRNA来降低内在无序的蛋白质 α-突触核蛋白水平
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2024-01-05
err8
errOAAI
errTong, Yuquan; Zhang, Peiyuan; Yang, Xueyi; Liu, Xiaohui; Zhang, Jie; Grudniewska, Magda; Jung, Ikrak; Abegg, Daniel; Liu, Jun; Childs-Disney, Jessica L.; Gibaut, Quentin M. R.; Haniff, Hafeez S.; Adibekian, Alexander; Mouradian, M. Maral; Disney, Matthew D.
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Altering the Cleaving Effector in Chimeric Molecules that Target RNA Enhances Cellular Selectivity改变靶向RNA的嵌合分子中的切割效应增强细胞选择性
errACS CHEMICAL BIOLOGY
IF3.8
err2023-10-12
err7
PREAI
errSuresh, Blessy M.; Tong, Yuquan; Abegg, Daniel; Adibekian, Alexander; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
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Transcriptome-Wide Studies of RNA-Targeted Small Molecules Provide a Simple and Selective r(CUG)exp Degrader in Myotonic Dystrophy
errACS CENTRAL SCIENCE
IF10.4
err2023-06-26
err7
errOAAI
errGibaut, Quentin M. R.; Bush, Jessica A.; Tong, Yuquan; Baisden, Jared T.; Taghavi, Amirhossein; Olafson, Hailey; Yao, Xiyuan; Childs-Disney, Jessica L.; Wang, Eric T.; Disney, Matthew D.
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Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA (vol 144, pg. 11260, 2022)
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2023-04-14
err0
PREAI
errTong, Yuquan; Gibaut, Quentin M. R.; Rouse, Warren; Childs-Disney, Jessica L.; Suresh, Blessy M.; Abegg, Daniel; Choudhary, Shruti; Akahori, Yoshihiro; Adibekian, Alexander; Moss, Walter N.; Disney, Matthew D.
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A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G4C2)exp in c9ALS/FTD via the nuclear RNA exosome
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-11-21
err10
errOAAI
errBush, Jessica A.; Meyer, Samantha M.; Fuerst, Rita; Tong, Yuquan; Li, Yue; Benhamou, Raphael, I; Aikawa, Haruo; Zanon, Patrick R. A.; Gibaut, Quentin M. R.; Angelbello, Alicia J.; Gendron, Tania F.; Zhang, Yong-Jie; Petrucelli, Leonard; Jensen, Torben Heick; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
err收藏
Targeting RNA structures with small molecules用小分子靶向RNA结构
errNATURE REVIEWS DRUG DISCOVERY
IF101.8
err2022-08-08
err230
errOAAI
errChilds-Disney, Jessica L.; Yang, Xueyi; Gibaut, Quentin M. R.; Tong, Yuquan; Batey, Robert T.; Disney, Matthew D.
err分享
err收藏
Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-06-23
err34
errOAAI
errTong, Yuquan; Gibaut, Quentin M. R.; Rouse, Warren; Childs-Disney, Jessica L.; Suresh, Blessy M.; Abegg, Daniel; Choudhary, Shruti; Akahori, Yoshihiro; Adibekian, Alexander; Moss, Walter N.; Disney, Matthew D.
err分享
err收藏
DNA-encoded library versus RNA-encoded library selection enables design of an oncogenic noncoding RNA inhibitor
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2022-02-02
err28
errOAAI
errBenhamou, Raphael I.; Suresh, Blessy M.; Tong, Yuquan; Cochran, Wesley G.; Cavett, Valerie; Vezina-Dawod, Simon; Abegg, Daniel; Childs-Disney, Jessica L.; Adibekian, Alexander; Paegel, Brian M.; Disney, Matthew D.
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A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype
errCELL CHEMICAL BIOLOGY
IF7.2
err2022-02-01
err19
errOAAI
errHaniff, Hafeez S.; Liu, Xiaohui; Tong, Yuquan; Meyer, Samantha M.; Knerr, Laurent; Lemurell, Malin; Abegg, Daniel; Aikawa, Haruo; Adibekian, Alexander; Disney, Matthew D.
err分享
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Bioinformatic Searching for Optimal RNA Targets of Dimeric Compounds Informs Design of a MicroRNA-27a Inhibitor
errACS CHEMICAL BIOLOGY
IF3.8
err2021-12-13
err5
errOAAI
errBenhamou, Raphael, I; Choudhary, Shruti; Lekah, Elizabeth; Tong, Yuquan; Disney, Matthew D.
err分享
err收藏
Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G4C2) repeat expansion in vitro and in vivo ALS models在体外和体内ALS模型中使用小分子减少的c9ALS/FTD r(G4C2) 重复扩增的核糖核酸酶募集
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2021-10-27
err46
errOAAI
errBush, Jessica A.; Aikawa, Haruo; Fuerst, Rita; Li, Yue; Ursu, Andrei; Meyer, Samantha M.; Benhamou, Raphael, I; Chen, Jonathan L.; Khan, Tanya; Wagner-Griffin, Sarah; Van Meter, Montina J.; Tong, Yuquan; Olafson, Hailey; McKee, Kendra K.; Childs-Disney, Jessica L.; Gendron, Tania F.; Zhang, Yongjie; Coyne, Alyssa N.; Wang, Eric T.; Yildirim, Ilyas; Wang, Kye Won; Petrucelli, Leonard; Rothstein, Jeffrey D.; Disney, Matthew D.
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Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment通过核糖核酸酶募集将蛋白质靶向的小分子药物重编程为RNA
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2021-08-13
err65
errOAAI
errZhang, Peiyuan; Liu, Xiaohui; Abegg, Daniel; Tanaka, Toru; Tong, Yuquan; Benhamou, Raphael I.; Baisden, Jared; Crynen, Gogce; Meyer, Samantha M.; Cameron, Michael D.; Chatterjee, Arnab K.; Adibekian, Alexander; Childs-Disney, Jessica L.; Disney, Matthew D.
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err收藏
Systematically Studying the Effect of Small Molecules Interacting with RNA in Cellular and Preclinical Models
errACS CHEMICAL BIOLOGY
IF3.8
err2021-06-24
err12
errOAAI
errBush, Jessica A.; Williams, Christopher C.; Meyer, Samantha M.; Tong, Yuquan; Haniff, Hafeez S.; Childs-Disney, Jessica L.; Disney, Matthew D.
err分享
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Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders用小分子结合剂和核糖核酸酶靶向嵌合体 (RIBOTAC) 降解剂靶向SARS-CoV-2 RNA基因组
errACS CENTRAL SCIENCE
IF10.4
err2020-09-30
err141
errOAAI
errHaniff, Hafeez S.; Tong, Yuquan; Liu, Xiaohui; Chen, Jonathan L.; Suresh, Blessy M.; Andrews, Ryan J.; Peterson, Jake M.; O'Leary, Collin A.; Benhamou, Raphael, I; Moss, Walter N.; Disney, Matthew D.
err分享
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研究方向

暂时未获取到该数据
合作学者
合作期刊
L
Leonard Petrucelli
H 指数: 113 · 论文数: 527
J
Jeffrey D. Rothstein
H 指数: 108 · 论文数: 345
刘军 封面图
刘军 (Jun Liu)
H 指数: 70 · 论文数: 1.1K
T
Tania F. Gendron
H 指数: 68 · 论文数: 189
M
M. Maral Mouradian
H 指数: 68 · 论文数: 243
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