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收藏Large-scale data mining of four billion human antibody variable regions reveals convergence between therapeutic and natural antibodies that constrains search space for biologics drug discovery
Dudzic, Pawel; Chomicz, Dawid; Konczak, Jaroslaw; Satlawa, Tadeusz; Janusz, Bartosz; Wrobel, Sonia; Gawlowski, Tomasz; Jaszczyszyn, Igor; Bielska, Weronika; Demharter, Samuel; Spreafico, Roberto; Schulte, Lukas; Martin, Kyle; Comeau, Stephen R.; Krawczyk, Konrad
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收藏Benchmarking antibody clustering methods using sequence, structural, and machine learning similarity measures for antibody discovery applications使用序列,结构和机器学习相似性度量对抗体发现应用程序进行基准测试的抗体聚类方法
Chomicz, Dawid; Konczak, Jaroslaw; Wrobel, Sonia; Satlawa, Tadeusz; Dudzic, Pawel; Janusz, Bartosz; Tarkowski, Mateusz; Deszynski, Piotr; Gawlowski, Tomasz; Kostyn, Anna; Orlowski, Marek; Klaus, Tomasz; Schulte, Lukas; Martin, Kyle; Comeau, Stephen R.; Krawczyk, Konrad
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收藏Structural basis for pH-insensitive inhibition of immunoglobulin G recycling by an anti-neonatal Fc receptor antibody
Kenniston, Jon A.; Taylor, Brandy M.; Conley, Gregory P.; Cosic, Janja; Kopacz, Kris J.; Lindberg, Allison P.; Comeau, Stephen R.; Atkins, Kateri; Bullen, Jameson; TenHoor, Christopher; Adelman, Burt A.; Sexton, Daniel J.; Edwards, Thomas E.; Nixon, Andrew E.
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收藏Breaking down the barrier restricting infiltration and differentiation of APC in the tumor microenvironment with a first-in-class antibody targeting Semaphorin4D, and rational combination therapies
Evans, Elizabeth E.; Bussler, Holm; Mallow, Crystal; Reilly, Christine; Torno, Sebold; Scrivens, Maria; Foster, Cathie; Howell, Alan; Comeau, Stephen R.; Balch, Leslie; Knapp, Alyssa; Leonard, John E.; Fisher, Terrence L.; Hu-Lieskovan, Siwen; Ribas, Antoni; Smith, Ernest S.; Zauderer, Maurice
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收藏Inhibition of Plasma Kallikrein by a Highly Specific Active Site Blocking Antibody
Kenniston, Jon A.; Faucette, Ryan R.; Martik, Diana; Comeau, Stephen R.; Lindberg, Allison P.; Kopacz, Kris J.; Conley, Gregory P.; Chen, Jie; Viswanathan, Malini; Kastrapeli, Niksa; Cosic, Janja; Mason, Shauna; DiLeo, Mike; Abendroth, Jan; Kuzmic, Petr; Ladner, Robert C.; Edwards, Thomas E.; TenHoor, Christopher; Adelman, Burt A.; Nixon, Andrew E.; Sexton, Daniel J.
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收藏Discovery and Characterization of a Fully Human Monoclonal Antibody Inhibitor of Plasma Kallikrein for the Treatment of Plasma Kallikrein-Mediated Edema
Sexton, Daniel; Faucette, Ryan; Viswanathan, Malini; Kastrapeli, Niksa; Kopacz, Kris; Conley, Greg; Lindberg, Allison; Cosic, Janja; Comeau, Stephen; Mason, Shauna; Kenniston, Jon; DiLeo, Mike; Chen, Jie; Ladner, Robert; Nixon, Andrew; TenHoor, Christopher
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收藏Achieving reliability and high accuracy in automated protein docking: ClusPro, PIPER, SOU, and stability analysis in CAPRI rounds 13-19在自动蛋白质对接中实现可靠性和高精度: ClusPro,PIPER,SOU和CAPRI第13-19轮中的稳定性分析
Kozakov, Dima; Hall, David R.; Beglov, Dmitri; Brenke, Ryan; Comeau, Stephen R.; Shen, Yang; Li, Keyong; Zheng, Jiefu; Vakili, Pirooz; Paschalidis, Ioannis Ch.; Vajda, Sandor
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