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J

Janine N. Copp

University of British Columbia

H指数:22

被引数:1,558

浏览量:0

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Correction: The biosynthesis of N-acyalated tryptazolone in Mycobacterium tuberculosis and related bacteria

更正：N-acyalated tryptazolone在结核分枝杆菌及相关细菌中的生物合成

Journal of Biological Chemistry

IF3.9

2026-03-060

OAAI

The biosynthesis of N-acyalated tryptazolone in Mycobacterium tuberculosis and related bacteria

Journal of Biological Chemistry

IF3.9

2025-12-200

OAAI

Expanding the biocatalytic and oxidative landscape of the old yellow enzyme family

扩展古老黄素酶家族的生物催化和氧化景观

Protein Science

IF5.2

2025-10-290

PRE

From Binding to Catalysis: Emergence of a Rudimentary Enzyme Conferring Intrinsic Antibiotic Resistance

从结合到催化：赋予固有抗生素耐药性的原始酶的出现

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2025-10-010

PRE

Deciphering the biosynthesis of a novel lipid in Mycobacterium tuberculosis expands the known roles of the nitroreductase superfamily

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-07-012

OAAI

A conserved SH3-like fold in diverse putative proteins tetramerizes into an oxidoreductase providing an antimicrobial resistance phenotype

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2023-01-117

OAAI

Discovery of Highly Trimethoprim-Resistant DfrB Dihydrofolate Reductases in Diverse Environmental Settings Suggests an Evolutionary Advantage Unrelated to Antibiotic Resistance

ANTIBIOTICS-BASEL

IF4.6

2022-12-074

OA

Interrogation of the Structure-Activity Relationship of a Lipophilic Nitroaromatic Prodrug Series Designed for Cancer Gene Therapy Applications

PHARMACEUTICALS

IF4.8

2022-02-012

OAAI

Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections

IF4.7

2020-10-2736

OAAI

E. coli nitroreductase NfsA is a reporter gene for non-invasive PET imaging in cancer gene therapy applications

IF13.3

2020-01-0120

OAAI

A revised biosynthetic pathway for the cofactor F420 in prokaryotes

NATURE COMMUNICATIONS

IF15.7

2019-04-0550

OAAI

Evaluating the abilities of diverse nitroaromatic prodrug metabolites to exit a model Gram negative vector for bacterial-directed enzyme-prodrug therapy

BIOCHEMICAL PHARMACOLOGY

IF5.6

2018-12-0112

OAAI

Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2017-10-24110

OAAI

Engineering a Multifunctional Nitroreductase for Improved Activation of Prodrugs and PET Probes for Cancer Gene Therapy

CELL CHEMICAL BIOLOGY

IF7.2

2017-03-0162

OAAI

Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapy

BIOCHEMICAL PHARMACOLOGY

IF5.6

2016-09-0117

PREAI

Nitroreductase gene-directed enzyme prodrug therapy: insights and advances toward clinical utility

BIOCHEMICAL JOURNAL

IF4.3

2015-10-02135

PREAI

Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104A

BIOCHEMICAL PHARMACOLOGY

IF5.6

2013-04-0148

PREAI

Targeted mutagenesis of the Vibrio fischeri flavin reductase FRase I to improve activation of the anticancer prodrug CB1954

BIOCHEMICAL PHARMACOLOGY

IF5.6

2012-09-0129

PREAI

Rapid and flexible biochemical assays for evaluating 4′-phosphopantetheinyl transferase activity

BIOCHEMICAL JOURNAL

IF4.3

2011-05-2751

PREAI

The phosphopantetheinyl transferase superfamily: Phylogenetic analysis and functional implications in cyanobacteria

APPLIED AND ENVIRONMENTAL MICROBIOLOGY

IF3.7

2006-04-0170

OAAI