未登录 Sequence specificity analysis of the SETD2 protein lysine methyltransferase and discovery of a SETD2 super-substrate (Sep, 10.1038/s42003-020-01223-6, 2020) Schuhmacher, Maren Kirstin; Beldar, Serap; Khella, Mina S.; Broehm, Alexander; Ludwig, Jan; Tempel, Wolfram; Weirich, Sara; Min, Jinrong; Jeltsch, Albert 分享 收藏
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Structural Basis for the Binding Selectivity of Human CDY Chromodomains Dong, Cheng; Liu, Yanli; Lyu, Tian-Jie; Beldar, Serap; Lamb, Kelsey N.; Tempel, Wolfram; Li, Yanjun; Li, Zoey; James, Lindsey, I; Qin, Su; Wang, Yun; Min, Jinrong 分享 收藏
Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex Zhang, Heng; Devoucoux, Maeva; Song, Xiaosheng; Li, Li; Ayaz, Gamze; Cheng, Harry; Tempel, Wolfram; Dong, Cheng; Loppnau, Peter; Cote, Jacques; Min, Jinrong 分享 收藏
Discovery of Small Molecule Antagonists of the USP5 Zinc Finger Ubiquitin-Binding Domain Mann, Mandeep K.; Franzoni, Ivan; de Freitas, Renato Ferreira; Tempel, Wolfram; Houliston, Scott; Smith, Leanna; Vedadi, Masoud; Arrowsmith, Cheryl H.; Harding, Rachel J.; Schapira, Matthieu 分享 收藏
The dynamic conformational landscape of the protein methyltransferase SETD8 Chen, Shi; Wiewiora, Rafal P.; Meng, Fanwang; Babault, Nicolas; Ma, Anqi; Yu, Wenyu; Qian, Kun; Hu, Hao; Zou, Hua; Wang, Junyi; Fan, Shijie; Blum, Gil; Pittella-Silva, Fabio; Beauchamp, Kyle A.; Tempel, Wolfram; Jiang, Hualiang; Chen, Kaixian; Skene, Robert J.; Zheng, Yujun George; Brown, Peter J.; Jin, Jian; Luo, Cheng; Chodera, John D.; Luo, Minkui 分享 收藏
A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 (vol 12, pg 180, 2016) Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Brown, Peter J.; TBedford, Mark; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
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The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding Madigan, James P.; Hou, Feng; Ye, Linlei; Hu, Jicheng; Dong, Aiping; Tempel, Wolfram; Yohe, Marielle E.; Randazzo, Paul A.; Jenkins, Lisa M. Miller; Gottesman, Michael M.; Tong, Yufeng 分享 收藏
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H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1 H3K14ac通过SETDB1的三重Tudor结构域与H3K9的甲基化相关 Jurkowska, Renata Z.; Qin, Su; Kungulovski, Goran; Tempel, Wolfram; Liu, Yanli; Bashtrykov, Pavel; Stiefelmaier, Judith; Jurkowski, Tomasz P.; Kudithipudi, Srikanth; Weirich, Sara; Tamas, Raluca; Wu, Hong; Dombrovski, Ludmila; Loppnau, Peter; Reinhardt, Richard; Min, Jinrong; Jeltsch, Albert 分享 收藏
First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor Moody, James D.; Levy, Shiri; Mathieu, Julie; Xing, Yalan; Kim, Woojin; Dong, Cheng; Tempel, Wolfram; Robitaille, Aaron M.; Dang, Luke T.; Ferreccio, Amy; Detraux, Damien; Sidhu, Sonia; Zhu, Licheng; Carter, Lauren; Xu, Chao; Valensisi, Cristina; Wang, Yuliang; Hawkins, R. David; Min, Jinrong; Moon, Randall T.; Orkin, Stuart H.; Baker, David; Ruohola-Baker, Hannele 分享 收藏
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Structure-Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase Butler, Kyle V.; Ma, Anqi; Yu, Wenyu; Li, Fengling; Tempel, Wolfram; Babault, Nicolas; Pittella-Silva, Fabio; Shao, Jason; Wang, Junyi; Luo, Minkui; Vedadi, Masoud; Brown, Peter J.; Arrowsmith, Cheryl H.; Jin, Jian 分享 收藏
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Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product Hughes, Scott J.; Barnard, Leanne; Mottaghi, Katayoun; Tempel, Wolfram; Antoshchenko, Tetyana; Hong, Bum Soo; Allali-Hassani, Abdellah; Smil, David; Vedadi, Masoud; Strauss, Erick; Park, Hee-Won 分享 收藏
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A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1 Stuckey, Jacob I.; Dickson, Bradley M.; Cheng, Nancy; Liu, Yanli; Norris, Jacqueline L.; Cholensky, Stephanie H.; Tempel, Wolfram; Qin, Su; Huber, Katherine G.; Sagum, Cari; Black, Karynne; Li, Fengling; Huang, Xi-Ping; Roth, Bryan L.; Baughman, Brandi M.; Senisterra, Guillermo; Pattenden, Samantha G.; Vedadi, Masoud; Browne, Peter J.; Bedford, Mark T.; Min, Jinrong; Arrowsmith, Cheryl H.; James, Lindsey I.; Frye, Stephen V. 分享 收藏
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