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L

Lin Tai

olivia newton-john cancer research institute
H指数:20
被引数:2,571

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教育背景

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工作经历

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荣誉奖项

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A high-density CRISPR activation platform for mapping cancer dependencies and resistance pathways ex vivo and in vivo

高密度CRISPR激活平台用于体外和体内绘制癌症依赖性和耐药通路

Science Advances
IF12.5
2026-09-180
OA
Sarah T. Diepstraten; Yexuan Deng; Margaret A. Potts; Amy Heidersbach; Christina König; Kristel M. Dorighi; Lin Tai; Andrew J. Kueh; Lauren Whelan; Catherine Chang; Felix Brown; Gemma L. Kelly; Jean-Philippe Fortin; Benjamin Haley; John E. La Marca; Marco J. Herold
Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening

通过结合AsCas12a基因敲入小鼠与超紧凑型筛选技术，推进基因工程工具箱的发展。

NATURE COMMUNICATIONS
IF15.7
2025-01-300
OA
Jin, Wei; Deng, Yexuan; La Marca, John E.; Lelliott, Emily J.; Diepstraten, Sarah T.; Konig, Christina; Tai, Lin; Snetkova, Valentina; Dorighi, Kristel M.; Hoberecht, Luke; Hedditch, Millicent G.; Whelan, Lauren; Healey, Geraldine; Fayle, Dan; Lau, Kieran; Potts, Margaret A.; Chen, Moore Z.; Johnston, Angus P. R.; Liao, Yang; Shi, Wei; Kueh, Andrew J.; Haley, Benjamin; Fortin, Jean-Philippe
Mouse models to investigate in situ cell fate decisions induced by p53
EMBO JOURNAL
IF8.3
2024-08-190
OAAI
Lieschke, Elizabeth; Thomas, Annabella F.; Kueh, Andrew; Atkin-Smith, Georgia K.; Baldoni, Pedro L.; La Marca, John E.; Young, Savannah; Huang, Allan Shuai; Ross, Aisling M.; Whelan, Lauren; Kaloni, Deeksha; Tai, Lin; Smyth, Gordon K.; Herold, Marco J.; Hawkins, Edwin D.; Strasser, Andreas; Kelly, Gemma L.
Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells
CANCER DISCOVERY
IF33.3
2023-10-2422
OAAI
Wang, Zilu; Burigotto, Matteo; Ghetti, Sabrina; Vaillant, Francois; Tan, Tao; Capaldo, Bianca D.; Palmieri, Michelle; Hirokawa, Yumiko; Tai, Lin; Simpson, Daniel S.; Chang, Catherine; Huang, Allan Shuai; Lieschke, Elizabeth; Diepstraten, Sarah T.; Kaloni, Deeksha; Riffkin, Chris; Huang, David C. S.; Li Wai Suen, Connie S. N.; Garnham, Alexandra L.; Gibbs, Peter; Visvader, Jane E.; Sieber, Oliver M.; Herold, Marco J.; Fava, Luca L.; Kelly, Gemma L.; Strasser, Andreas
Generation of a CRISPR activationmouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance (vol 13, 4739, 2022)
NATURE COMMUNICATIONS
IF15.7
2022-08-250
OAAI
Deng, Yexuan; Diepstraten, Sarah T.; Potts, Margaret A.; Giner, Goknur; Trezise, Stephanie; Ng, Ashley P.; Healey, Gerry; Kane, Serena R.; Cooray, Amali; Behrens, Kira; Heidersbach, Amy; Kueh, Andrew J.; Pal, Martin; Wilcox, Stephen; Tai, Lin; Alexander, Warren S.; Visvader, Jane E.; Nutt, Stephen L.; Strasser, Andreas; Haley, Benjamin; Zhao, Quan; Kelly, Gemma L.; Herold, Marco J.
Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance
NATURE COMMUNICATIONS
IF15.7
2022-08-1214
OAAI
Deng, Yexuan; Diepstraten, Sarah T.; Potts, Margaret A.; Giner, Goeknur; Trezise, Stephanie; Ng, Ashley P.; Healey, Gerry; Kane, Serena R.; Cooray, Amali; Behrens, Kira; Heidersbach, Amy; Kueh, Andrew J.; Pal, Martin; Wilcox, Stephen; Tai, Lin; Alexander, Warren S.; Visvader, Jane E.; Nutt, Stephen L.; Strasser, Andreas; Haley, Benjamin; Zhao, Quan; Kelly, Gemma L.; Herold, Marco J.
Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

多种细胞死亡途径的灵活使用和相互联系可防止细胞内感染

IMMUNITY
IF26.3
2020-09-0198
OAAI
Doerflinger, Marcel; Deng, Yexuan; Whitney, Paul; Salvamoser, Ranja; Engel, Sven; Kueh, Andrew J.; Tai, Lin; Bachem, Annabell; Gressier, Elise; Geoghegan, Niall D.; Wilcox, Stephen; Rogers, Kelly L.; Garnham, Alexandra L.; Dengler, Michael A.; Bader, Stefanie M.; Ebert, Gregor; Pearson, Jaclyn S.; De Nardo, Dominic; Wang, Nancy; Yang, Chenying; Pereira, Milton; Bryant, Clare E.; Strugnell, Richard A.; Vince, James E.; Pellegrini, Marc; Strasser, Andreas; Bedoui, Sammy; Herold, Marco J.
Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects
CELL REPORTS
IF6.9
2019-04-0147
OAAI
Delbridge, Alex R. D.; Kueh, Andrew J.; Ke, Francine; Zamudio, Natasha M.; El-Saafin, Farrah; Jansz, Natasha; Wang, Gao-Yuan; Iminitoff, Megan; Beck, Tamara; Haupt, Sue; Hu, Yifang; May, Rose E.; Whitehead, Lachlan; Tai, Lin; Chiang, William; Herold, Marco J.; Haupt, Ygal; Smyth, Gordon K.; Thomas, Tim; Blewitt, Marnie E.; Strasser, Andreas; Voss, Anne K.
Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner
IMMUNITY
IF26.3
2018-03-0166
OAAI
O'Reilly, Lorraine A.; Putoczki, Tracy L.; Mielke, Lisa A.; Low, Jun T.; Lin, Ann; Preaudet, Adele; Herold, Marco J.; Yaprianto, Kelvin; Tai, Lin; Kueh, Andrew; Pacini, Guido; Ferrero, Richard L.; Gugasyan, Raffi; Hu, Yifang; Christie, Michael; Wilcox, Stephen; Grumont, Raelene; Griffin, Michael D. W.; O'Connor, Liam; Smyth, Gordon K.; Ernst, Mathias; Waring, Paul; Gerondakis, Steve; Strasser, Andreas

研究方向

暂未获取到该数据
A
Andreas Strasser
H 指数:135论文数:816被引数:8.4万
M
Marco J. Herold
H 指数:58论文数:416被引数:1.3万
A
Andrew J. Kueh
H 指数:30论文数:148被引数:3,974
G
Gemma L. Kelly
H 指数:36论文数:262被引数:8,085
S
Stephen Wilcox
H 指数:32论文数:136被引数:4,310
S
Sarah T. Diepstraten
H 指数:13论文数:209被引数:1,335
Y
Yexuan Deng
H 指数:13论文数:48被引数:1,255
G
Gordon K. Smyth
H 指数:113论文数:595被引数:22.8万
M
Margaret A. Potts
H 指数:5论文数:19被引数:150
M
Martin Pál
H 指数:39论文数:105被引数:5,769