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S

Sigurd Lenzen

institute of experimental diabetes research

54H指数
287论文数
1.4W被引数
收录论文 96
发表时间
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Regulation of pancreatic beta-cell mass and its importance for antidiabetic therapies调节胰腺β细胞质量及其对抗糖尿病疗法的重要性
errJOURNAL OF MOLECULAR MEDICINE-JMM
IF4.2
err2026-09-18
err0
errOAAI
errSigurd Lenzen
err分享
err收藏
Comment on the role of interferons in the pathology of beta cell destruction in type 1 diabetes评论干扰素在1型糖尿病 β 细胞破坏病理中的作用
errDIABETOLOGIA
IF10.2
err2024-09-07
err1
errOAAI
errLenzen, Sigurd
err分享
err收藏
PNLIPRP1 Hypermethylation in Exocrine Pancreas Links Type 2 Diabetes and Cholesterol Metabolism
errDIABETES
IF7.5
err2024-08-13
err1
PREAI
errMaurin, Lucas; Marselli, Lorella; Boissel, Mathilde; Ning, Lijiao; Boutry, Raphael; Fernandes, Justine; Suleiman, Mara; De Luca, Carmela; Leloire, Audrey; Pascat, Vincent; Toussaint, Benedicte; Amanzougarene, Souhila; Derhourhi, Mehdi; Joerns, Anne; Lenzen, Sigurd; Pattou, Francois; Kerr-Conte, Julie; Canouil, Mickael; Marchetti, Piero; Bonnefond, Amelie; Froguel, Philippe; Khamis, Amna
err分享
err收藏
Mechanisms of lipotoxicity-induced dysfunction and death of human pancreatic beta cells under obesity and type 2 diabetes conditions
errOBESITY REVIEWS
IF7.4
err2024-02-07
err5
errOAAI
errPloetz, Thomas; Lenzen, Sigurd
err分享
err收藏
Differential effects of saturated and unsaturated free fatty acids on ferroptosis in rat ,?-cells
errJOURNAL OF NUTRITIONAL BIOCHEMISTRY
IF4.9
err2022-08-01
err25
PREAI
errKruemmel, Bastian; von Hanstein, Anna-Sophie; Ploetz, Thomas; Lenzen, Sigurd; Mehmeti, Ilir
err分享
err收藏
The pro-radical hydrogen peroxide as a stable hydroxyl radical distributor: lessons from pancreatic beta cells
errARCHIVES OF TOXICOLOGY
IF6.9
err2022-04-13
err31
errOAAI
errLenzen, Sigurd; Lushchak, Volodymyr I.; Scholz, Fritz
err分享
err收藏
The importance of aquaporin-8 for cytokine-mediated toxicity in rat insulin-producing cells
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2021-10-01
err12
PREAI
errKrueger, Christina; Joerns, Anne; Kaynert, Jonas; Waldeck-Weiermair, Markus; Michel, Thomas; Elsner, Matthias; Lenzen, Sigurd
err分享
err收藏
Remission of autoimmune diabetes by anti-TCR combination therapies with anti-IL-17A or/and anti-IL-6 in the IDDM rat model of type 1 diabetes
errBMC MEDICINE
IF8.3
err2020-02-28
err13
errOAAI
errJoerns, Anne; Ishikawa, Daichi; Teraoku, Hiroki; Yoshimoto, Toshiaki; Wedekind, Dirk; Lenzen, Sigurd
err分享
err收藏
Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes
errDIABETES
IF7.5
err2020-01-23
err33
errOAAI
errJoerns, Anne; Wedekind, Dirk; Jaehne, Joachim; Lenzen, Sigurd
err分享
err收藏
Asymmetric dimethylation and citrullination in the LEW.1AR1-iddm rat, an animal model of human type 1 diabetes, and effects of anti-TCR/anti-TNF-α antibody-based therapy
errAMINO ACIDS
IF2.4
err2019-12-12
err3
PREAI
errBollenbach, Alexander; Tsikas, Dimitrios; Lenzen, Sigurd; Joerns, Anne
err分享
err收藏
MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity
errCELL DEATH & DISEASE
IF9.6
err2019-01-10
err13
errOAAI
errTyka, Karolina; Joerns, Anne; Turatsinze, Jean-Valery; Eizirik, Decio L.; Lenzen, Sigurd; Gurgul-Convey, Ewa
err分享
err收藏
Light-induced intracellular hydrogen peroxide generation through genetically encoded photosensitizer KillerRed-SOD1
errFREE RADICAL RESEARCH
IF2.9
err2018-12-26
err7
PREAI
errLaporte, Anna; Nordenbrock, Anke; Lenzen, Sigurd; Elsner, Matthias
err分享
err收藏
β-Cell DNA Damage Response Promotes Islet Inflammation in Type 1 DiabetesΒ 细胞DNA损伤反应促进1型糖尿病胰岛炎症
errDIABETES
IF7.5
err2018-08-27
err44
errOAAI
errHorwitz, Elad; Krogvold, Lars; Zhitomirsky, Sophia; Swisa, Avital; Fischman, Maya; Lax, Tsuria; Dahan, Tehila; Hurvitz, Noa; Weinberg-Corem, Noa; Klochendler, Agnes; Powers, Alvin C.; Brissova, Marcela; Joerns, Anne; Lenzen, Sigurd; Glaser, Benjamin; Dahl-Jorgensen, Knut; Dor, Yuval
err分享
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Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings
errAMINO ACIDS
IF2.4
err2018-05-04
err21
errOAAI
errTsikas, Dimitrios; Hanff, Erik; Bollenbach, Alexander; Kruger, Ruan; Vu Vi Pham; Chobanyan-Juergens, Kristine; Wedekind, Dirk; Arndt, Tanja; Joerns, Anne; Berbee, Jimmy F. P.; Princen, Hans M. G.; Luecke, Thomas; Mariotti, Francois; Huneau, Jean-Francois; Ueckert, Stefan; Froelich, Jurgen C.; Lenzen, Sigurd
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Immune cell and cytokine patterns in children with type 1 diabetes mellitus undergoing a remission phase: A longitudinal study
errPEDIATRIC DIABETES
IF5.6
err2018-03-27
err24
errOAAI
errFitas, Ana Laura; Martins, Catarina; Borrego, Luis Miguel; Lopes, Lurdes; Joerns, Anne; Lenzen, Sigurd; Limbert, Catarina
err分享
err收藏
An editorial on the article 'Patents in the Diabetes Area in the Years 2008-2016'
errEXPERT OPINION ON THERAPEUTIC PATENTS
IF4.6
err2018-01-15
err0
errOAAI
errLenzen, Sigurd
err分享
err收藏
Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicitysphingosine-1-phosphate裂解酶的过表达保护胰岛素分泌细胞免受细胞因子毒性
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2017-12-01
err33
errOAAI
errHahn, Claudine; Tyka, Karolina; Saba, Julie D.; Lenzen, Sigurd; Gurgul-Convey, Ewa
err分享
err收藏
Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes来自器官供体和胰腺切除患者的IMIDIA生物库的系统生物学定义了2型糖尿病患者胰岛的新型转录组学特征
errDIABETOLOGIA
IF10.2
err2017-11-28
err119
errOAAI
errSolimena, Michele; Schulte, Anke M.; Marselli, Lorella; Ehehalt, Florian; Richter, Daniela; Kleeberg, Manuela; Mziaut, Hassan; Knoch, Klaus-Peter; Parnis, Julia; Bugliani, Marco; Siddiq, Afshan; Joerns, Anne; Burdet, Frederic; Liechti, Robin; Suleiman, Mara; Margerie, Daniel; Syed, Farooq; Distler, Marius; Gruetzmann, Robert; Petretto, Enrico; Moreno-Moral, Aida; Wegbrod, Carolin; Soenmez, Anke; Pfriem, Katja; Friedrich, Anne; Meinel, Joern; Wollheim, Claes B.; Baretton, Gustavo B.; Scharfmann, Raphael; Nogoceke, Everson; Bonifacio, Ezio; Sturm, Dorothee; Meyer-Puttlitz, Birgit; Boggi, Ugo; Saeger, Hans-Detlev; Filipponi, Franco; Lesche, Mathias; Meda, Paolo; Dahl, Andreas; Wigger, Leonore; Xenarios, Ioannis; Falchi, Mario; Thorens, Bernard; Weitz, Juergen; Bokvist, Krister; Lenzen, Sigurd; Rutter, Guy A.; Froguel, Philippe; von Buelow, Manon; Ibberson, Mark; Marchetti, Piero
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miRNome Profiling of Purified Endoderm and Mesoderm Differentiated from hESCs Reveals Functions of miR-483-3p and miR-1263 for Cell-Fate Decisions
errSTEM CELL REPORTS
IF5.1
err2017-11-01
err27
errOAAI
errIshikawa, Daichi; Diekmann, Ulf; Fiedler, Jan; Just, Annette; Thum, Thomas; Lenzen, Sigurd; Naujok, Ortwin
err分享
err收藏
ER-resident antioxidative GPx7 and GPx8 enzyme isoforms protect insulinsecreting INS-1E β-cells against lipotoxicity by improving the ER antioxidative capacity
errFREE RADICAL BIOLOGY AND MEDICINE
IF8.2
err2017-11-01
err48
PREAI
errMehmeti, Ilir; Lortz, Stephan; Avezov, Edward; Joerns, Anne; Lenzen, Sigurd
err分享
err收藏

研究方向

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合作学者
合作期刊
P
Philippe Froguel
H 指数: 163 · 论文数: 1.2K
D
David Ron
H 指数: 130 · 论文数: 422
C
Chantal Mathieu
H 指数: 127 · 论文数: 2.3K
G
Günter Klöppel
H 指数: 117 · 论文数: 742
T
Thomas Thum
H 指数: 109 · 论文数: 705
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