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Partial Pressure of Oxygen-Guided Adrenal Venous Sampling in Primary Aldosteronism 氧分压引导的库欣综合征肾上腺静脉采血术 Kei Omata, MD, PhD; Yuta Tezuka, MD, PhD; Hiromitsu Tannai, MD, PhD; Yoshikiyo Ono, MD, PhD; Hiroshi Ishihata, MD, PhD; Hiroki Kamada, MD, PhD; Sota Oguro, MD, PhD; Yoshihide Kawasaki, MD, PhD; Akihiro Ito, MD, PhD; Yuto Yamazaki, MD, PhD; Hironobu Sasano, MD, PhD; Takashi Suzuki, MD, PhD; Tetsuhiro Tanaka, MD, PhD; Kei Takase, MD, PhD; Hideki Katagiri, MD, PhD; Fumitoshi Satoh, MD, PhD; null 分享 收藏
Identification of substituted acetanilide compounds as small molecule CBX2 inhibitors via in silico screening 通过计算机筛选鉴定出取代的乙酰苯胺类化合物作为小分子CBX2抑制剂 Takase, Shohei; Kumar, Ashutosh; Yokoyama, Sho; Maemoto, Yuki; Aoki, Komei; Arata, Mayumi; Maruo, Hiroki; Dohi, Sayaka; Yun, Young Sook; Inoue, Hideshi; Hamamoto, Makiko; Yoshida, Minoru; Zhang, Kam Y. J.; Ito, Akihiro 分享 收藏
Reduction of H3K9 methylation by G9a inhibitors improves the development of mouse SCNT embryos Matoba, Shogo; Shikata, Daiki; Shirai, Fumiyuki; Tatebe, Takaki; Hirose, Michiko; Nakata, Akiko; Watanabe, Naomi; Hasegawa, Ayumi; Ito, Akihiro; Yoshida, Minoru; Ogura, Atsuo 分享 收藏
Ligand-based design and synthesis of new trityl histamine and trityl cysteamine derivatives as SIRT2 inhibitors for cancer therapy 基于配体的新型三苯甲基组胺和三苯甲基半胱胺衍生物的设计与合成，作为SIRT2抑制剂用于癌症治疗 Badran, Mostafa M.; Abbas, Samar H.; Tateishi, Hiroshi; Maemoto, Yuki; Toma, Tsugumasa; Ito, Akihiro; Fujita, Mikako; Otsuka, Masami; Abdel-Aziz, Mohamed; Radwan, Mohamed O. 分享 收藏
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Lysine long-chain fatty acylation regulates the TEAD transcription factor Noritsugu, Kota; Suzuki, Takehiro; Dodo, Kosuke; Ohgane, Kenji; Ichikawa, Yasue; Koike, Kota; Morita, Satoshi; Umehara, Takashi; Ogawa, Kenji; Sodeoka, Mikiko; Dohmae, Naoshi; Yoshida, Minoru; Ito, Akihiro 分享 收藏
Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents Nishigaya, Yosuke; Takase, Shohei; Sumiya, Tatsunobu; Kikuzato, Ko; Sato, Tomohiro; Niwa, Hideaki; Sato, Shin; Nakata, Akiko; Sonoda, Takeshi; Hashimoto, Noriaki; Namie, Ryosuke; Honma, Teruki; Umehara, Takashi; Shirouzu, Mikako; Koyama, Hiroo; Yoshida, Minoru; Ito, Akihiro; Shirai, Fumiyuki 分享 收藏
Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis DNA甲基转移酶3B的S-亚硝基化在肿瘤发生的表观遗传调控中的关键作用 Okuda, Kosaku; Nakahara, Kengo; Ito, Akihiro; Iijima, Yuta; Nomura, Ryosuke; Kumar, Ashutosh; Fujikawa, Kana; Adachi, Kazuya; Shimada, Yuki; Fujio, Satoshi; Yamamoto, Reina; Takasugi, Nobumasa; Onuma, Kunishige; Osaki, Mitsuhiko; Okada, Futoshi; Ukegawa, Taichi; Takeuchi, Yasuo; Yasui, Norihisa; Yamashita, Atsuko; Marusawa, Hiroyuki; Matsushita, Yosuke; Katagiri, Toyomasa; Shibata, Takahiro; Uchida, Koji; Niu, Sheng-Yong; Lang, Nhi B.; Nakamura, Tomohiro; Zhang, Kam Y. J.; Lipton, Stuart A.; Uehara, Takashi 分享 收藏
A specific G9a inhibitor unveils BGLT3 lncRNA as a universal mediator of chemically induced fetal globin gene expression 一种特定的G9a抑制剂揭示了BGLT3 lncRNA作为化学诱导的胎儿珠蛋白基因表达的通用介质 Takase, Shohei; Hiroyama, Takashi; Shirai, Fumiyuki; Maemoto, Yuki; Nakata, Akiko; Arata, Mayumi; Matsuoka, Seiji; Sonoda, Takeshi; Niwa, Hideaki; Sato, Shin; Umehara, Takashi; Shirouzu, Mikako; Nishigaya, Yosuke; Sumiya, Tatsunobu; Hashimoto, Noriaki; Namie, Ryosuke; Usui, Masaya; Ohishi, Tomokazu; Ohba, Shun-ichi; Kawada, Manabu; Hayashi, Yoshihiro; Harada, Hironori; Yamaguchi, Tokio; Shinkai, Yoichi; Nakamura, Yukio; Yoshida, Minoru; Ito, Akihiro 分享 收藏
Low-energy shock wave therapy ameliorates ischemic-induced overactive bladder in a rat model Kimura, Shingo; Kawamorita, Naoki; Kikuchi, Yoku; Shindo, Tomohiko; Ishizuka, Yuichi; Satake, Yoichi; Sato, Takuma; Izumi, Hideaki; Yamashita, Shinichi; Yasuda, Satoshi; Shimokawa, Hiroaki; Ito, Akihiro 分享 收藏
Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1a chromodomain in living cells Sasaki, Kazuki; Suzuki, Michihiro; Sonoda, Takeshi; Schneider-Poetsch, Tilman; Ito, Akihiro; Takagi, Motoki; Fujishiro, Shinya; Sohtome, Yoshihiro; Dodo, Kosuke; Umehara, Takashi; Aburatani, Hiroyuki; Shin-ya, Kazuo; Nakao, Yoichi; Sodeoka, Mikiko; Yoshida, Minoru 分享 收藏
Discovery of Benzylpiperazine Derivatives as CNS-Penetrant and Selective Histone Deacetylase 6 Inhibitors Hashimoto, Kosuke; Ide, Soichiro; Arata, Mayumi; Nakata, Akiko; Ito, Akihiro; Ito, Takashi K.; Kudo, Norio; Lin, Bangzhong; Nunomura, Kazuto; Tsuganezawa, Keiko; Yoshida, Minoru; Nagaoka, Yasuo; Sumiyoshi, Takaaki 分享 收藏
Retusone A, a Guaiane-Type Sesquiterpene Dimer from Wikstroemia retusa and Its Inhibitory Effects on Histone Acetyltransferase HBO1 Expression Yun, Young Sook; Nakano, Tomomi; Fukaya, Haruhiko; Hitotsuyanagi, Yukio; Nakamura, Miho; Umetsu, Megumi; Matsushita, Nobuko; Miyake, Katsunori; Fuchino, Hiroyuki; Kawahara, Nobuo; Moriya, Fuki; Ito, Akihiro; Takahashi, Yuji; Inoue, Hideshi 分享 收藏
Improved development of mouse somatic cell nuclear transfer embryos by chlamydocin analogues, class I and IIa histone deacetylase inhibitors Kamimura, Satoshi; Inoue, Kimiko; Mizutani, Eiji; Kim, Jin-Moon; Inoue, Hiroki; Ogonuki, Narumi; Miyamoto, Kei; Ihashi, Shunya; Itami, Nobuhiko; Wakayama, Teruhiko; Ito, Akihiro; Nishino, Norikazu; Yoshida, Minoru; Ogura, Atsuo 分享 收藏
Piperidine-4-carboxamide as a new scaffold for designing secretory glutaminyl cyclase inhibitors Dileep, K., V; Sakai, Naoki; Ihara, Kentaro; Kato-Murayama, Miyuki; Nakata, Akiko; Ito, Akihiro; Sivaraman, D. M.; Shin, Jay W.; Yoshida, Minoru; Shirouzu, Mikako; Zhang, Kam Y. J. 分享 收藏
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Antiproliferative S-Trityl-l-Cysteine -Derived Compounds as SIRT2 Inhibitors: Repurposing and Solubility Enhancement Radwan, Mohamed O.; Ciftci, Halil I.; Ali, Taha F. S.; Ellakwa, Doha E.; Koga, Ryoko; Tateishi, Hiroshi; Nakata, Akiko; Ito, Akihiro; Yoshida, Minoru; Okamoto, Yoshinari; Fujita, Mikako; Otsuka, Masami 分享 收藏
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