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K

Krittikorn Kümpornsin

Wellcome Sanger Institute
H指数:15
被引数:934

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Plasmodium falciparum HSP90 inhibitors show divergent resistance despite a shared ATP-binding site

恶性疟原虫HSP90抑制剂表现出差异性耐药性，尽管具有共同的ATP结合位点

Cell Reports
IF6.9
2026-07-010
PRE
Ko, Fu-Hsuan; Lukens, Amanda K.; de Souza, Mariana Laureano; Foy, Alex; Hsiao, Jason; Ndiaye, Tolla; Okombo, John; Yeo, Tomas; Park, Heekuk; Uhlemann, Anne-Catrin; Boonyalai, Nonlawat; Kumpornsin, Krittikorn; Girling, Gareth; Pasaje, Charisse; Godoy, Luiz; Kapoor, Priyan; Durst, Gregory L.; Ottilie, Sabine; Chatterjee, Arnab; Niles, Jacquin; Lee, Marcus; Fidock, David A.; Wirth, Dyann F.; Winzeler, Elizabeth A.
Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase
NATURE COMMUNICATIONS
IF15.7
2024-01-312
OAAI
Xie, Stanley C.; Wang, Yinuo; Morton, Craig J.; Metcalfe, Riley D.; Dogovski, Con; Pasaje, Charisse Flerida A.; Dunn, Elyse; Luth, Madeline R.; Kumpornsin, Krittikorn; Istvan, Eva S.; Park, Joon Sung; Fairhurst, Kate J.; Ketprasit, Nutpakal; Yeo, Tomas; Yildirim, Okan; Bhebhe, Mathamsanqa N.; Klug, Dana M.; Rutledge, Peter J.; Godoy, Luiz C.; Dey, Sumanta; De Souza, Mariana Laureano; Siqueira-Neto, Jair L.; Du, Yawei; Puhalovich, Tanya; Amini, Mona; Shami, Gerry; Loesbanluechai, Duangkamon; Nie, Shuai; Williamson, Nicholas; Jana, Gouranga P.; Maity, Bikash C.; Thomson, Patrick; Foley, Thomas; Tan, Derek S.; Niles, Jacquin C.; Han, Byung Woo; Goldberg, Daniel E.; Burrows, Jeremy; Fidock, David A.; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Griffin, Michael D. W.; Todd, Matthew H.; Tilley, Leann
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-03-0811
OA
Istvan, Eva S.; Guerra, Francisco; Abraham, Matthew; Huang, Kuo-Sen; Rocamora, Frances; Zhao, Haoshuang; Xu, Lan; Pasaje, Charisse; Kumpornsin, Krittikorn; Luth, Madeline R.; Cui, Haissi; Yang, Tuo; Diaz, Sara Palomo; Gomez-Lorenzo, Maria G.; Qahash, Tarrick; Mittal, Nimisha; Ottilie, Sabine; Niles, Jacquin; Lee, Marcus C. S.; Llinas, Manue; Kato, Nobutaka; Okombo, John; Fidock, David A.; Schimmel, Paul; Gamo, Francisco Javier; Goldberg, Daniel E.; Winzeler, Elizabeth A.
A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin
NATURE COMMUNICATIONS
IF15.7
2022-09-3032
OAAI
Qiu, Deyun; Pei, Jinxin V.; Rosling, James E. O.; Thathy, Vandana; Li, Dongdi; Xue, Yi; Tanner, John D.; Penington, Jocelyn Sietsma; Aw, Yi Tong Vincent; Aw, Jessica Yi Han; Xu, Guoyue; Tripathi, Abhai K.; Gnadig, Nina F.; Yeo, Tomas; Fairhurst, Kate J.; Stokes, Barbara H.; Murithi, James M.; Kumpornsin, Krittikorn; Hasemer, Heath; Dennis, Adelaide S. M.; Ridgway, Melanie C.; Schmitt, Esther K.; Straimer, Judith; Papenfuss, Anthony T.; Lee, Marcus C. S.; Corry, Ben; Sinnis, Photini; Fidock, David A.; van Dooren, Giel G.; Kirk, Kiaran; Lehane, Adele M.
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
CELL CHEMICAL BIOLOGY
IF7.2
2022-02-0145
OAAI
Summers, Robert L.; Pasaje, Charisse Flerida A.; Pisco, Joao P.; Striepen, Josefine; Luth, Madeline R.; Kumpornsin, Krittikorn; Carpenter, Emma F.; Munro, Justin T.; Lin, De; Plater, Andrew; Punekar, Avinash S.; Shepherd, Andrew M.; Shepherd, Sharon M.; Vanaerschot, Manu; Murithi, James M.; Rubiano, Kelly; Akidi, Asli; Ottilie, Sabine; Mittal, Nimisha; Dilmore, A. Hazel; Won, Madalyn; Mandt, Rebecca E. K.; McGowen, Kerry; Owen, Edward; Walpole, Chris; Llinas, Manuel; Lee, Marcus C. S.; Winzeler, Elizabeth A.; Fidock, David A.; Gilbert, Ian H.; Wirth, Dyann F.; Niles, Jacquin C.; Baragana, Beatriz; Lukens, Amanda K.
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
Science
IF45.8
2022-01-010
OAAI
Stanley C. Xie; Riley D. Metcalfe; Elyse A. Dunn; Craig J. Morton; Shih‐Chung Huang; Tanya Puhalovich; Yawei Du; Sergio Wittlin; Shuai Nie; Madeline R. Luth; Li‐Ting Ma; Mi-Sook Kim; Charisse Flerida A. Pasaje; Krittikorn Kümpornsin; Carlo Giannangelo; Fiona J. Houghton; Alisje Churchyard; Mufuliat Toyin Famodimu; Daniel C. Barry; David L. Gillett; Sumanta Dey; Clara C. Kosasih; William Newman; Jacquin C. Niles; Lee M; Jake Baum; Sabine Ottilie; Elizabeth A. Winzeler; Darren J. Creek; Nicholas A. Williamson; Michael W. Parker; Stephen L. Brand; Steven Langston; Lawrence R. Dick; Michael D. W. Griffin; Alexandra E. Gould; Leann M. Tilley
The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites
CELL CHEMICAL BIOLOGY
IF7.2
2020-02-0152
OAAI
Yoo, Euna; Schulze, Christopher J.; Stokes, Barbara H.; Onguka, Ouma; Yeo, Tomas; Mok, Sachel; Gnadig, Nina F.; Zhou, Yani; Kurita, Kenji; Foe, Ian T.; Terrell, Stephanie M.; Boucher, Michael J.; Cieplak, Piotr; Kumpornsin, Krittikorn; Lee, Marcus C. S.; Linington, Roger G.; Long, Jonathan Z.; Uhlemann, Anne-Catrin; Weerapana, Eranthie; Fidock, David A.; Bogyo, Matthew
Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine
INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE
IF3.4
2019-04-0135
OAAI
Loesbanluechai, Duangkamon; Kotanan, Namfon; de Cozar, Cristina; Kochakarn, Theerarat; Ansbro, Megan R.; Chotivanich, Kesinee; White, Nicholas J.; Wilairat, Prapon; Lee, Marcus C. S.; Javier Gamo, Francisco; Maria Sanz, Laura; Chookajorn, Thanat; Kumpornsin, Krittikorn

研究方向

暂未获取到该数据
L
Lee M
H 指数:48论文数:356被引数:1.0万
D
David A. Fidock
H 指数:95论文数:427被引数:3.3万
E
Elizabeth A. Winzeler
H 指数:83论文数:356被引数:3.6万
T
Thanat Chookajorn
H 指数:21论文数:58被引数:2,156
M
Madeline R. Luth
H 指数:19论文数:47被引数:1,369
C
Charisse Flerida A. Pasaje
H 指数:23论文数:111被引数:2,055
T
Tomas Yeo
H 指数:23论文数:77被引数:2,126
N
Nicholas J. White
H 指数:186论文数:2,043被引数:13.8万
K
Kesinee Chotivanich
H 指数:58论文数:217被引数:1.7万
D
Duangkamon Loesbanluechai
H 指数:6论文数:21被引数:141