未登录 Physiologically-Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges 基于生理学的药代动力学建模以支持儿科临床开发:IQ工作组关于当前状况和挑战的观点 Yates, James W. T.; Zientek, Michael; Taskar, Kunal S.; Lin, Wen; Heimbach, Tycho; Willmann, Stefan; Rehmel, Jessica; Parrott, Neil; Hanley, Michael; Badee, Justine; Chen, Yuan; Cole, Susan; De Zwart, Loeckie; Haertter, Sebastian; Jiang, Rongrong; Kotsuma, Masakatsu; Liang, Guiqing; Lin, Yu-Wei; Liu, Jing; Ou, Ying; Rascher, Juliane; Shaik, Naveed A.; Wahlstrom, Jan; Wang, Xiaofeng; Xiao, Guangqing; Yee, Ka Lai; Cheung, S. Y. Amy 分享 收藏
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Quantitative Systems Pharmacology Model to Predict Target Occupancy by Bruton Tyrosine Kinase Inhibitors in Patients With B-Cell Malignancies Demin, Oleg; Ou, Ying; Kolesova, Galina; Shchelokov, Dmitry; Stepanov, Alexander; Musatova, Veronika; Sahasranaman, Sri; Zhao, Yating; Liu, Xiangyu; Tang, Zhiyu; Hanley, William D. 分享 收藏
A randomized, placebo-controlled trial of the BTK inhibitor zanubrutinib in hospitalized patients with COVID-19 respiratory distress: immune biomarker and clinical findings Treon, Steven P.; Kotton, Camille N.; Park, David J.; Moranzoni, Giorgia; Lemvigh, Camilla K.; Gathe Jr, Joseph C.; Varughese, Tilly A.; Barnett, Christopher F.; Belenchia, Johnny M.; Clark, Nina M.; Farber, Charles M.; Abid, Muhammad Bilal; Ahmed, Gulrayz; Patterson, Christopher J.; Guerrera, Maria L.; Soumerai, Jacob D.; Chea, Vipheaviny A.; Carulli, Isabel P.; Southard, Jackson; Li, Shuqiang; Wu, Catherine J.; Livak, Kenneth J.; Holmgren, Eric; Kim, Pil; Shi, Carrie; Lin, Holly; Ramakrishnan, Vanitha; Ou, Ying; Olszewski, Scott; Olsen, Lars Ronn; Keskin, Derin B.; Hunter, Zachary R.; Tankersley, Christopher; Zimmerman, Todd; Dhakal, Binod 分享 收藏
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Evaluation of drug interaction potential of zanubrutinib with cocktail probes representative of CYP3A4, CYP2C9, CYP2C19, P-gp and BCRP Ou, Ying C.; Tang, Zhiyu; Novotny, William; Tawashi, Manal; Li, Ta-Kai; Coleman, Hugh A.; Sahasranaman, Srikumar 分享 收藏
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No QTc Prolongation With Zanubrutinib: Results of Concentration-QTc Analysis From a Thorough QT Study in Healthy Subjects Mu, Song; Darpo, Borje; Tang, Zhiyu; Novotny, William; Tawashi, Manal; Xue, Hongqi; Willett, Michael; Lin, Leo; Sahasranaman, Sri; Ou, Ying C. 分享 收藏
Ambient pressure dried flexible silica aerogel for construction of monolithic shape-stabilized phase change materials Gao, Hongyi; Bo, Lijie; Liu, Panpan; Chen, Dangjia; Li, Ang; Ou, Ying; Dong, Cheng; Wang, Jingjing; Chen, Xiaobo; Hou, Changmin; Dong, Wenjun; Wang, Ge 分享 收藏
Physiologically-based pharmacokinetic modelling to predict oprozomib CYP3A drug-drug interaction potential in patients with advanced malignancies Ou, Ying; Xu, Yang; Gore, Lia; Harvey, R. Donald; Mita, Alain; Papadopoulos, Kyriakos P.; Wang, Zhengping; Cutler, Richard E.; Pinchasik, Dawn E.; Tsimberidou, Apostolia M. 分享 收藏
Pharmacokinetics of carfilzomib in patients with advanced malignancies and varying degrees of hepatic impairment: an open-label, single-arm, phase 1 study Brown, Jennifer; Plummer, Ruth; Bauer, Todd M.; Anthony, Stephen; Sarantopoulos, John; De Vos, Filip; White, Mike; Schupp, Marco; Ou, Ying; Vaishampayan, Ulka 分享 收藏