未登录Targeting KIFC1 to disrupt centrosome clustering and trigger anaphase catastrophe in small-cell lung cancer靶向KIFC1以破坏中心体聚集并诱导小细胞肺癌中的后期灾难
Nakagawa, Natsuki; Toda, Minemichi; Kunita, Akiko; Horie, Masafumi; Tokunaga, Masakatsu; Ikushima, Hiroaki; Ka, Mirei; Iida, Takahiro; Shigeoka, Manabu; Ito, Yukinobu; Ando, Takahiro; Watanabe, Kousuke; Ota, Yasunori; Liu, Xi; Dmitrovsky, Ethan; Kage, Hidenori; Kawakami, Masanori .png)
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收藏KIFC1 inhibition elicits antineoplastic activity in small cell lung cancer by inducing anaphase catastropheNakagawa, Natsuki; Tokunaga, Masakatsu; Ka, Mirei; Sugiura, Yuriko; Iida, Takahiro; Ando, Takahiro; Watanabe, Kousuke; Liu, Xi; Dmitrovsky, Ethan; Kage, Hidenori; Kawakami, Masanori 分享 收藏 A novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironmentWei, Cheng-Hsin; Huang, Lu; Kreh, Blair; Liu, Xiuxia; Tyutyunyk-Massey, Liliya; Kawakami, Masanori; Chen, Zibo; Shi, Mi; Kozlov, Serguei; Chan, King C.; Andresson, Thorkell; Carrington, Mary; Vuligonda, Vidyasagar; Sanders, Martin E.; Horowitz, Amir; Hwu, Patrick; Peng, Weiyi; Dmitrovsky, Ethan; Liu, Xi 分享 收藏 分享 收藏 Combining a novel retinoic acid receptor-γ agonist with immune checkpoint blockade represses lung cancer growth in vivoWei, Cheng-Hsin; Huang, Lu; Kreh, Blair; Liu, Xiuxia; Tyutyunyk-Massey, Liliya; Chen, Zibo; Shi, Mi; Vuligonda, Vidyasagar; Sanders, Martin; Kozlov, Serguei; Chan, King; Horowitz, Amir; Carrington, Mary; Hwu, Patrick; Peng, Weiyi; Dmitrovsky, Ethan; Liu, Xi 分享 收藏 Loss of ubiquitin-specific peptidase 18 destabilizes 14-3-3ζ protein and represses lung cancer metastasisChen, Zibo; Zheng, Lin; Chen, Yulong; Liu, Xiuxia; Kawakami, Masanori; Mustachio, Lisa Maria; Roszik, Jason; Ferry-Galow, Katherine V.; Parchment, Ralph E.; Liu, Xin; Andresson, Thorkell; Duncan, Gerard; Kurie, Jonathan M.; Rodriguez-Canales, Jaime; Liu, Xi; Dmitrovsky, Ethan 分享 收藏 A Novel CDK2/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid CancersKawakami, Masanori; Mustachio, Lisa Maria; Chen, Yulong; Chen, Zibo; Liu, Xiuxia; Wei, Cheng-Hsin; Roszik, Jason; Kittai, Adam S.; Danilov, Alexey, V; Zhang, Xiaoshan; Fang, Bingliang; Wang, Jing; Heymach, John, V; Tyutyunyk-Massey, Liliya; Freemantle, Sarah J.; Kurie, Jonathan M.; Liu, Xi; Dmitrovsky, Ethan 分享 收藏 The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer GrowthLiu, Xi; Lu, Yun; Chen, Zibo; Liu, Xiuxia; Hu, Weiguo; Zheng, Lin; Chen, Yulong; Kurie, Jonathan M.; Shi, Mi; Mustachio, Lisa Maria; Adresson, Thorkell; Fox, Stephen; Roszik, Jason; Kawakami, Masanori; Freemantle, Sarah J.; Dmitrovsky, Ethan 分享 收藏 A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint componentsNilsson, Monique B.; Sun, Huiying; Robichaux, Jacqulyne; Pfeifer, Matthias; McDermott, Ultan; Travers, Jon; Diao, Lixia; Xi, Yuanxin; Tong, Pan; Shen, Li; Hofstad, Mia; Kawakami, Masanori; Le, Xiuning; Liu, Xi; Fan, Youhong; Poteete, Alissa; Hu, Limei; Negrao, Marcelo, V; Tran, Hai; Dmitrovsky, Ethan; Peng, David; Gibbons, Don L.; Wang, Jing; Heymach, John, V 分享 收藏 USP18 promotes lipolysis, fatty acid oxidation and lung cancer growthLiu, Xi; Lu, Yun; Chen, Zibo; Liu, Xiuxia; Hu, Weiguo; Zheng, Lin; Chen, Yulong; Shi, Mi; Mustachio, Lisa; Roszik, Jason; Kawakami, Masanori; Freemantle, Sarah; Dmitrovsky, Ethan 分享 收藏 Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and PolyploidyZheng, Lin; Chen, Zibo; Kawakami, Masanori; Chen, Yulong; Roszik, Jason; Mustachio, Lisa Maria; Kurie, Jonathan M.; Villalobos, Pamela; Lu, Wei; Behrens, Carmen; Mino, Barbara; Solis, Luisa M.; Silvester, Jennifer; Thu, Kelsie L.; Cescon, David W.; Rodriguez-Canales, Jaime; Wistuba, Ignacio I.; Mak, Tak W.; Liu, Xi; Dimitrovsky, Ethan 分享 收藏 Loss of the ubiquitin-specific peptidase 18 (USP18) reduces lung cancer metastasisChen, Zibo; Zheng, Lin; Chen, Yulong; Kawakami, Masanori; Mustachio, Lisa; Roszik, Jason; Liu, Xin; Kurie, Jonathan; Liu, Xi; Dmitrovsky, Ethan 分享 收藏 All-trans-retinoic acid (ATRA) markedly augments anti-tumor immunityHuang, Lu; Chen, Zibo; Williams, Leila; Chen, Yulong; Wang, Yunfei; Kawakami, Masanori; Roszik, Jason; Hwu, Patrick; Dmitrovsky, Ethan; Peng, Weiyi; Liu, Xi 分享 收藏 分享 收藏 分享 收藏 REPLY TO OEGEMA ET AL.: CFI-400945 and Polo-like kinase 4 inhibitionKawakami, Masanori; Mustachio, Lisa Maria; Zheng, Lin; Chen, Yulong; Rodriguez-Canales, Jaime; Mino, Barbara; Kurie, Jonathan M.; Roszik, Jason; Villalobos, Pamela Andrea; Thu, Kelsie L.; Silvester, Jennifer; Cescon, David W.; Wistuba, Ignacio I.; Mak, Tak W.; Liu, Xi; Dmitrovsky, Ethan 分享 收藏 CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 BlockadeCD38-Mediated免疫抑制作为肿瘤细胞逃避PD-1/PD-L1阻断的机制Chen, Limo; Diao, Lixia; Yang, Yongbin; Yi, Xiaohui; Rodriguez, Leticia; Li, Yanli; Villalobos, Pamela A.; Cascone, Tina; Liu, Xi; Tan, Lin; Lorenzi, Philip L.; Huang, Anfei; Zhao, Qiang; Peng, Di; Fradette, Jared J.; Peng, David H.; Ungewiss, Christin; Roybal, Jonathon; Tong, Pan; Oba, Junna; Skoulidis, Ferdinandos; Peng, Weiyi; Carter, Brett W.; Gay, Carl M.; Fan, Youhong; Class, Caleb A.; Zhu, Jingfen; Rodriguez-Canales, Jaime; Kawakami, Masanori; Byers, Lauren Averett; Woodman, Scott E.; Papadimitrakopoulou, Vassiliki A.; Dmitrovsky, Ethan; Wang, Jing; Ullrich, Stephen E.; Wistuba, Ignacio I.; Heymach, John V.; Qin, F. Xiao-Feng; Gibbons, Don L. 分享 收藏 Loss of ubiquitin-specific peptidase 18 (USP18) destabilizes the regulator of thermogenesis uncoupling protein-1 (UCP-1) and represses lung cancer growthLiu, Xi; Lu, Yun; Hu, Weiguo; Chen, Zibo; Mustachio, Lisa M.; Roszik, Jason; Zheng, Lin; Kawakami, Masanori; Chen, Yulong; Freemantle, Sarah J.; Dmitrovsky, Ethan 分享 收藏 Polo-like kinase 4 inhibition produces polyploidy and apoptotic death of lung cancersKawakami, Masanori; Mustachio, Lisa Maria; Zheng, Lin; Chen, Yulong; Rodriguez-Canales, Jaime; Mino, Barbara; Kurie, Jonathan M.; Roszik, Jason; Villalobos, Pamela Andrea; Thu, Kelsie L.; Cescon, David W.; Silvester, Jennifer; Wistuba, Ignacio; Mak, Tak W.; Liu, Xi; Dmitrovsky, Ethan 分享 收藏 分享 收藏 
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