未登录Precision off-the-shelf natural killer cell therapies for oncology with logic-gated gene circuits
Frankel, Nicholas W.; Deng, Han; Yucel, Gozde; Gainer, Marcus; Leemans, Nelia; Lam, Alice; Li, Yongshuai; Hung, Michelle; Lee, Derrick; Lee, Chen -Ting; Banicki, Andrew; Tian, Mengxi; Almudhfar, Niran; Naitmazi, Lawrence; Roguev, Assen; Lee, Seunghee; Wong, Wilson; Gordley, Russell; Lu, Timothy K.; Garrison, Brian S. .png)
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收藏分享 收藏 SENTI-401, AN ALLOGENEIC LOGIC-GATED AND MULTIARMED CAR-NK CELL THERAPY FOR THE TREATMENT OF CEA-EXPRESSING SOLID TUMORS WITH ENHANCED SELECTIVITY AND EFFICACYJunca, Alba Gonzalez; Frankel, Nicholas; Morvan, Maelig; Roguev, Assen; Hung, Michelle; Gordley, Russell; Palermo, Miguel; Santomaso, Tyler; Chinta, Pearley; Sotelo, Aldo; Gainer, Marcus; Lee, Derrick; Hua, Tony; Banicki, Andrew; Tian, Mengxi; Almudhfar, Niran; Contreras, Atahualpa; Lee, Chen-Ting; Lu, Timothy 分享 收藏 Thioredoxin-related protein 32 is an arsenite-regulated thiol reductase of the proteasome 19 S particle (vol 284, pg 15233, 2009)Wiseman, R. Luke; Chin, King-Tung; Haynes, Cole M.; Stanhill, Ariel; Xu, Chong-Feng; Roguev, Assen; Krogan, Nevan J.; Neubert, Thomas A.; Ron, David 分享 收藏 A Quantitative Genetic Interaction Map of HIV InfectionGordon, David E.; Watson, Ariane; Roguev, Assen; Zheng, Simin; Jang, Gwendolyn M.; Kane, Joshua; Xu, Jiewei; Guo, Jeffrey Z.; Stevenson, Erica; Swaney, Danielle L.; Franks-Skiba, Kathy; Verschueren, Erik; Shales, Michael; Crosby, David C.; Frankel, Alan D.; Marson, Alexander; Marazzi, Ivan; Cagney, Gerard; Krogan, Nevan J. 分享 收藏 分享 收藏 Genetic interaction mapping in mammalian cells using CRISPR interferenceDu, Dan; Roguev, Assen; Gordon, David E.; Chen, Meng; Chen, Si-Han; Shales, Michael; Shen, John Paul; Ideker, Trey; Mali, Prashant; Qi, Lei S.; Krogan, Nevan J. 分享 收藏 Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactionsShen, John Paul; Zhao, Dongxin; Sasik, Roman; Luebeck, Jens; Birmingham, Amanda; Bojorquez-Gomez, Ana; Licon, Katherine; Klepper, Kristin; Pekin, Daniel; Beckett, Alex N.; Sanchez, Kyle Salinas; Thomas, Alex; Kuo, Chih-Chung; Du, Dan; Roguev, Assen; Lewis, Nathan E.; Chang, Aaron N.; Kreisberg, Jason F.; Krogan, Nevan; Qi, Lei; Ideker, Trey; Mali, Prashant 分享 收藏 Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent CellsDing, Li; Paszkowski-Rogacz, Maciej; Winzi, Maria; Chakraborty, Debojyoti; Theis, Mirko; Singh, Sukhdeep; Ciotta, Giovanni; Poser, Ina; Roguev, Assen; Chu, Wai Kit; Choudhary, Chunaram; Mann, Matthias; Stewart, A. Francis; Krogan, Nevan; Buchholz, Frank 分享 收藏 分享 收藏 分享 收藏 Identification of evolutionarily conserved genetic interactions in DNA mismatch repairTosti, Elena; Katakowski, Joseph A.; Schaetzlein, Sonja; Kim, Hyun-Soo; Ryan, Colm J.; Shales, Michael; Roguev, Assen; Krogan, Nevan J.; Palliser, Deborah; Keogh, Michael-Christopher; Edelmann, Winfried 分享 收藏 Identification of a BET Family Bromodomain/Casein Kinase II/TAF-Containing Complex as a Regulator of Mitotic Condensin FunctionKim, Hyun-Soo; Mukhopadhyay, Rituparna; Rothbart, Scott B.; Silva, Andrea C.; Vanoosthuyse, Vincent; Radovani, Ernest; Kislinger, Thomas; Roguev, Assen; Ryan, Colm J.; Xu, Jiewei; Jahari, Harlizawati; Hardwick, Kevin G.; Greenblatt, Jack F.; Krogan, Nevan J.; Fillingham, Jeffrey S.; Strahl, Brian D.; Bouhassira, Eric E.; Edelmann, Winfried; Keogh, Michael-Christopher 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Hierarchical Modularity and the Evolution of Genetic Interactomes across SpeciesRyan, Colm J.; Roguev, Assen; Patrick, Kristin; Xu, Jiewei; Jahari, Harlizawati; Tong, Zongtian; Beltrao, Pedro; Shales, Michael; Qu, Hong; Collins, Sean R.; Kliegman, Joseph I.; Jiang, Lingli; Kuo, Dwight; Tosti, Elena; Kim, Hyun-Soo; Edelmann, Winfried; Keogh, Michael-Christopher; Greene, Derek; Tang, Chao; Cunningham, Padraig; Shokat, Kevan M.; Cagney, Gerard; Svensson, J. Peter; Guthrie, Christine; Espenshade, Peter J.; Ideker, Trey; Krogan, Nevan J. 分享 收藏 Yeast SREBP Cleavage Activation Requires the Golgi Dsc E3 Ligase ComplexStewart, Emerson V.; Nwosu, Christine C.; Tong, Zongtian; Roguev, Assen; Cummins, Timothy D.; Kim, Dong-Uk; Hayles, Jacqueline; Park, Han-Oh; Hoe, Kwang-Lae; Powell, David W.; Krogan, Nevan J.; Espenshade, Peter J. 分享 收藏 An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombeKim, Hyun-Soo; Vanoosthuyse, Vincent; Fillingham, Jeffrey; Roguev, Assen; Watt, Stephen; Kislinger, Thomas; Treyer, Alex; Carpenter, Laura Rocco; Bennett, Christopher S.; Emili, Andrew; Greenblatt, Jack F.; Hardwick, Kevin G.; Krogan, Nevan J.; Baehler, Juerg; Keogh, Michael-Christopher 分享 收藏 The Schizosaccharomyces pombe JmjC-Protein, Msc1, Prevents H2A.Z Localization in Centromeric and Subtelomeric Chromatin DomainsBuchanan, Luke; Durand-Dubief, Mickael; Roguev, Assen; Sakalar, Cagri; Wilhelm, Brian; Stralfors, Annelie; Shevchenko, Anna; Aasland, Rein; Shevchenko, Andrej; Ekwall, Karl; Stewart, A. Francis 分享 收藏 
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