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Francesca Spyrakis

istituto di biofisica (ibf-cnr)

34H指数
177论文数
3.9K被引数
收录论文 87
发表时间
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Two birds with one stone: An antibiotic hit blocking Staphylococcus aureus heme uptake with serendipitous hemoglobin left-shifting activity一石二鸟：一种抗生素候选物通过阻断金黄色葡萄球菌血红素摄取并意外具有血红蛋白左移活性
erriScience
IF4.1
err2026-05-15
err0
PREAI
errHijazi, Sarah; Marchesani, Francesco; Marchetti, Marialaura; Comani, Valeria Buoli; Brear, Paul; Campanini, Barbara; Ronda, Luca; Faggiano, Serena; Gianquinto, Eleonora; Hassankiade, Somayeh Asgharpour; Rolando, Barbara; Spyrakis, Francesca; Compari, Carlotta; Lazzarato, Loretta; De Bei, Omar; Frangipani, Emanuela; Bettati, Stefano
err分享
err收藏
Targeting ALDH7A1 with covalent inhibitors reveals new chemical space for prostate cancer therapy靶向ALDH7A1的共价抑制剂揭示了前列腺癌治疗的新化学空间
errJournal of Enzyme Inhibition and Medicinal Chemistry
IF5.4
err2026-05-11
err0
errOAAI
errRaffaella Gallo; Antonio Scarano; Eleonora Gianquinto; Gaia Franzini; Giulia Antonini; Serena Montalbano; Camillo Palmieri; Paola Conti; Francesca Spyrakis; Chiara Borsari; Stefano Bruno
err分享
err收藏
De novo acyl carrier proteins display structure-independent modification and sequence novelty从头酰基载体蛋白展示结构无关修饰和序列新颖性
errrsc chem. biol.
IF0
err2026-04-27
err0
errOAAI
errMichael Andrés Herrera; Grace King; Zoe Ozols; Gioele Tiburtini; Nicoletta Schiavo; Francesca Spyrakis; Louise Charkoudian; Dominic James Campopiano
err分享
err收藏
Antibacterial PROTACs: the road ahead for next-generation antibiotics?抗菌PROTACs：下一代抗生素的未来之路？
errDrug Discovery Today
IF7.5
err2026-04-01
err0
errOAAI
errAndrea Milelli; Simone Raimondi; Somayeh Asgharpour; Jean-Denis Docquier; Francesca Spyrakis
err分享
err收藏
Calcium as a molecular switch that regulates Annexin A11 N- and C-terminal domains interaction and its role in ALS钙作为分子开关，调控Annexin A11 N端和C端结构域的相互作用及其在ALS中的作用
errInternational Journal of Biological Macromolecules
IF8.5
err2026-03-28
err0
errOAAI
errGiulia Di Napoli; Lorenzo Alfurno; Alex Fissore; Eleonora Raccuia; Paolo Olivieri; Mauro Marengo; Simonetta Oliaro-Bosso; Fabrizio Dal Piaz; Gianluca Catucci; Gianfranco Gilardi; Adrian Velazquez-Campoy; Filippo Prischi; Angela De Simone; Francesca Spyrakis; Francesco Di Palma; Salvatore Adinolfi
err分享
err收藏
Toward Integrative Predictive Toxicology: Advanced Methods for Drug Toxicity and Safety Prediction面向整合预测毒理学：药物毒性和安全性预测的先进方法
errWIREs Computational Molecular Science
IF0
err2026-02-19
err0
errOAAI
errEleonora Gianquinto; Matteo Bersani; Lucrezia Armando; Lara Davani; Clara Cena; Angela De Simone; Francesca Spyrakis
err分享
err收藏
Correction: PFOA biomonitoring and kidney cancer risk: a meta-analysis of serum levels更正：PFOA生物监测与肾癌风险：血清水平的一项荟萃分析
errFrontiers in Oncology
IF3.3
err2025-11-08
err0
errOAAI
errFrancesca Spyrakis†; Gioele Antonio Tiburtini†; Stefania Bruno†; Tommaso A. Dragani†; Francesca Colombo†
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PFOA biomonitoring and kidney cancer risk: a meta-analysis of serum levels全氟辛酸生物监测与肾癌风险：血清水平的荟萃分析
errFrontiers in Oncology
IF3.3
err2025-08-02
err0
errOAAI
errFrancesca Spyrakis†; Gioele Antonio Tiburtini†; Stefania Bruno†; Tommaso A. Dragani†; Francesca Colombo†
err分享
err收藏
AR-A014418-based dual Glycogen Synthase Kinase 3β/Histone Deacetylase inhibitors as potential therapeutics for Alzheimer's disease基于AR-A014418的双靶点糖原合成酶激酶3β/组蛋白去乙酰化酶抑制剂作为阿尔茨海默病的潜在治疗药物
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-06-10
err0
errOAAI
errAlan Santini; Elisa Tassinari; Alessandra Altomare; Manuela Loi; Elisabetta Ciani; Stefania Trazzi; Rebecca Piccarducci; Simona Daniele; Claudia Martini; Barbara Pagliarani; Andrea Tarozzi; Matteo Bersani; Francesca Spyrakis; Daniela Danková; Eleonora Poeta; Simone Raimondi; Lara Davani; Giancarlo Aldini; Vincenza Andrisano; Angela De Simone; Andrea Milelli
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err收藏
First-in-class inhibitors of SbnA reduce siderophore production in Staphylococcus aureusSbnA的首创性抑制剂可降低金黄色葡萄球菌 siderophore 的产量
errFEBS JOURNAL
IF4.2
err2025-04-02
err0
errOAAI
errSarah Hijazi; Monica Cozzi; Somayeh Asgharpour; Omar De Bei; Serena Faggiano; Francesco Marchesani; Luca Ronda; Marialaura Marchetti; Eleonora Gianquinto; Mariacristina Failla; Gauthier Trèves; Loretta Lazzarato; Francesca Spyrakis; Barbara Campanini; Emanuela Frangipani; Stefano Bettati
err分享
err收藏
Opportunities and Challenges of Arginase Inhibitors in Cancer: A Medicinal Chemistry Perspective
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-11-19
err0
PREAI
errFailla, Mariacristina; Molaro, Maria Cristina; Schiano, Marica Erminia; Serafini, Marta; Tiburtini, Gioele Antonio; Gianquinto, Eleonora; Scoccia, Riccardo; Battisegola, Chiara; Rimoli, Maria Grazia; Chegaev, Konstantin; Ercolano, Giuseppe; Lazzarato, Loretta; Spyrakis, Francesca; Sodano, Federica
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err收藏
Novel NLRP3 inhibitor INF195: Low doses provide effective protection against myocardial ischemia/reperfusion injury
errVASCULAR PHARMACOLOGY
IF3.5
err2024-09-01
err5
errOAAI
errGastaldi, Simone; Giordano, Magali; Blua, Federica; Rubeo, Chiara; Boscaro, Valentina; Femmino, Saveria; Comita, Stefano; Gianquinto, Eleonora; Landolfi, Vanessa; Marini, Elisabetta; Gallicchio, Margherita; Spyrakis, Francesca; Pagliaro, Pasquale; Bertinaria, Massimo; Penna, Claudia
err分享
err收藏
In silico prediction of the interaction of legacy and novel per- and poly-fluoroalkyl substances (PFAS) with selected human transporters and of their possible accumulation in the human body
errARCHIVES OF TOXICOLOGY
IF6.9
err2024-06-17
err0
errOAAI
errTiburtini, G. A.; Bertarini, L.; Bersani, M.; Dragani, T. A.; Rolando, B.; Binello, A.; Barge, A.; Spyrakis, F.
err分享
err收藏
First in Class Dual Non-ATP-Competitive Glycogen Synthase Kinase 3β/Histone Deacetylase Inhibitors as a Potential Therapeutic to Treat Alzheimer's Disease
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2024-05-15
err0
PREAI
errSantini, Alan; Tassinari, Elisa; Poeta, Eleonora; Loi, Manuela; Ciani, Elisabetta; Trazzi, Stefania; Piccarducci, Rebecca; Daniele, Simona; Martini, Claudia; Pagliarani, Barbara; Tarozzi, Andrea; Bersani, Matteo; Spyrakis, Francesca; Dankova, Daniela; Olsen, Christian A.; Soldati, Roberto; Tumiatti, Vincenzo; Montanari, Serena; De Simone, Angela; Milelli, Andrea
err分享
err收藏
Identification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore
errSCIENTIFIC REPORTS
IF3.9
err2024-04-09
err0
errOAAI
errCozzi, Monica; Failla, Mariacristina; Gianquinto, Eleonora; Kovachka, Sandra; Comani, Valeria Buoli; Compari, Carlotta; De Bei, Omar; Giaccari, Roberta; Marchesani, Francesco; Marchetti, Marialaura; Ronda, Luca; Rolando, Barbara; Baroni, Massimo; Cruciani, Gabriele; Campanini, Barbara; Bettati, Stefano; Faggiano, Serena; Lazzarato, Loretta; Spyrakis, Francesca
err分享
err收藏
Structure-guided optimization of 3-hydroxybenzoisoxazole derivatives as inhibitors of Aldo-keto reductase 1C3 (AKR1C3) to target prostate cancer3-羟基苯并异恶唑衍生物作为醛酮还原酶1C3 (AKR1C3) 抑制剂靶向前列腺癌的结构指导优化
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-03-01
err4
errOAAI
errPippione, Agnese Chiara; Kovachka, Sandra; Vigato, Chiara; Bertarini, Laura; Mannella, Iole; Sainas, Stefano; Rolando, Barbara; Denasio, Enrica; Piercy-Mycock, Helen; Romalho, Linda; Salladini, Edoardo; Adinolfi, Salvatore; Zonari, Daniele; Peraldo-Neia, Caterina; Chiorino, Giovanna; Passoni, Alice; Mirza, Osman Asghar; Frydenvang, Karla; Pors, Klaus; Lolli, Marco Lucio; Spyrakis, Francesca; Oliaro-Bosso, Simonetta; Boschi, Donatella
err分享
err收藏
Antiherpetic Activity of a Root Exudate from Solanum lycopersicum
errMICROORGANISMS
IF4.2
err2024-02-11
err0
errOAAI
errBajetto, Greta; Arnodo, Davide; Biolatti, Matteo; Trifiro, Linda; Albano, Camilla; Pasquero, Selina; Gugliesi, Francesca; Campo, Eva; Spyrakis, Francesca; Prandi, Cristina; De Andrea, Marco; Dell'Oste, Valentina; Visentin, Ivan; Blangetti, Marco
err分享
err收藏
Structure-Based Optimization of 1,2,4-Triazole-3-Thione Derivatives: Improving Inhibition of NDM-/VIM-Type Metallo-β-Lactamases and Synergistic Activity on Resistant Bacteria
errPHARMACEUTICALS
IF4.8
err2023-12-02
err2
errOAAI
errBersani, Matteo; Failla, Mariacristina; Vascon, Filippo; Gianquinto, Eleonora; Bertarini, Laura; Baroni, Massimo; Cruciani, Gabriele; Verdirosa, Federica; Sannio, Filomena; Docquier, Jean-Denis; Cendron, Laura; Spyrakis, Francesca; Lazzarato, Loretta; Tondi, Donatella; Lopes, Bruno Silvester; Hanafiah, Alfizah
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Computational methods for protein characterization: in memoriam of Donald Abraham
errFRONTIERS IN MOLECULAR BIOSCIENCES
IF4
err2023-09-15
err0
errOAAI
errSpyrakis, Francesca; Kellogg, Glen E.
err分享
err收藏
Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2023-09-01
err16
errOAAI
errGastaldi, Simone; Rocca, Carmine; Gianquinto, Eleonora; Granieri, Maria Concetta; Boscaro, Valentina; Blua, Federica; Rolando, Barbara; Marini, Elisabetta; Gallicchio, Margherita; De Bartolo, Anna; Romeo, Naomi; Mazza, Rosa; Fedele, Francesco; Pagliaro, Pasquale; Penna, Claudia; Spyrakis, Francesca; Bertinaria, Massimo; Angelone, Tommaso
err分享
err收藏

研究方向

暂无研究方向
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