未登录
分享
收藏
分享
收藏
分享
收藏Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects
Tran, Kien; Sainsily, Xavier; Cote, Jerome; Coquerel, David; Couvineau, Pierre; Saibi, Sabrina; Haroune, Lounes; Besserer-Offroy, Elie; Flynn-Robitaille, Joel; Rojas, Martin Resua; Murza, Alexandre; Longpre, Jean-Michel; Auger-Messier, Mannix; Lesur, Olivier; Bouvier, Michel; Marsault, Eric; Boudreault, Pierre-Luc; Sarret, Philippe
分享
收藏Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients
Coquerel, David; Lamoureux, Julie; Chagnon, Frederic; Tran, Kien; Sage, Michael; Fortin-Pellerin, Etienne; Delile, Eugenie; Sainsily, Xavier; Fournier, Justin; Dumont, Audrey-Ann; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric; Praud, Jean-Paul; Fulop, Tamas; Lesur, Olivier
分享
收藏Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile
Tran, Kien; Van den Hauwe, Robin; Sainsily, Xavier; Couvineau, Pierre; Cote, Jerome; Simard, Louise; Echevarria, Marco; Murza, Alexandre; Serre, Alexandra; Theroux, Lea; Saibi, Sabrina; Haroune, Lounes; Longpre, Jean-Michel; Lesur, Olivier; Auger-Messier, Mannix; Spino, Claude; Bouvier, Michel; Sarret, Philippe; Ballet, Steven; Marsault, Eric
分享
收藏Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor
Tran, Kien; Murza, Alexandre; Sainsily, Xavier; Delile, Eugenie; Couvineau, Pierre; Cote, Jerome; Coquerel, David; Peloquin, Maude; Auger-Messier, Mannix; Bouvier, Michel; Lesur, Olivier; Sarret, Philippe; Marsault, Eric
分享
收藏Hypertonic sodium lactate improves microcirculation, cardiac function, and inflammation in a rat model of sepsis高渗乳酸钠改善脓毒症大鼠模型的微循环,心脏功能和炎症
Besnier, Emmanuel; Coquerel, David; Kouadri, Geoffrey; Clavier, Thomas; Favory, Raphael; Duburcq, Thibault; Lesur, Olivier; Bekri, Soumeya; Richard, Vincent; Mulder, Paul; Tamion, Fabienne
分享
收藏
分享
收藏
分享
收藏
分享
收藏The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment
Besserer-Offroy, Elie; Berube, Patrick; Cote, Jerome; Murza, Alexandre; Longpre, Jean-Michel; Dumaine, Robert; Lesur, Olivier; Auger-Messier, Mannix; Leduc, Richard; Marsault, Eric; Sarret, Philippe
分享
收藏A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects
Tran, Kien; Murza, Alexandre; Sainsily, Xavier; Coquerel, David; Cote, Jerome; Belleville, Karine; Haroune, Lounes; Longpre, Jean-Michel; Dumaine, Robert; Salvail, Dany; Lesur, Olivier; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric
分享
收藏
分享
收藏
分享
收藏ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic ShockELABELA可改善致命的实验性败血症休克的心肾结局
Coquerel, David; Chagnon, Frederic; Sainsily, Xavier; Dumont, Lauralyne; Murza, Alexandre; Cote, Jerome; Dumaine, Robert; Sarret, Philippe; Marsault, Eric; Salvail, Dany; Auger-Messier, Mannix; Lesur, Olivier
分享
收藏
分享
收藏
分享
收藏Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions
Murza, Alexandre; Sainsily, Xavier; Coquerel, David; Cote, Jerome; Marx, Patricia; Besserer-Offroy, Elie; Longpre, Jean-Michel; Laine, Jean; Reversade, Bruno; Salvail, Dany; Leduc, Richard; Dumaine, Robert; Lesur, Olivier; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric
分享
收藏
分享
收藏