logo
科言猫学术研究的AI总结
language
手机端手机端
  • Phone Feature微信小程序
简体中文简体中文
notice消息通知
博客博客
delete
arrow
返回
P

Philippe Sarret

universite de sherbrooke

50H指数
222论文数
6.4K被引数
收录论文 95
发表时间
logo
Docking of virtual libraries identifies small-molecule agonists of neurotensin receptors with analgesic activity虚拟库的对接鉴定出具有镇痛活性的神经tensin受体小分子激动剂
errNature Communications
IF15.7
err2026-07-22
err0
errOAAI
errNicolas Panel; Duy Duc Vo; Harald Hübner; Mattia Deluigi; Szymon Pach; Félix Bélair; Dorothee Weikert; Christoph Klenk; Mark Hilge; Niharika Shiva; Isabelle Brochu; Jean-Michel Longpré; Frida Bällgren; Aljona Saleh; Huabin Hu; Jon Kapla; Stefanie Kampen; Israel Cabeza de Vaca; Jan Kihlberg; Nina Wettschureck; Philippe Sarret; Andreas Plückthun; Peter Gmeiner; Jens Carlsson
err分享
err收藏
Improved brain penetration of neurotensin(8–13) via blood-brain barrier shuttle conjugation underlies strong analgesia通过血脑屏障穿梭偶联改善神经tensin(8–13)的脑渗透性，是其强效镇痛作用的基础
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-05-23
err0
errOAAI
errCamille Lagard; Jérôme Côté; Nathan Meneboo; Shauna Barreto; Michael Desgagné; Sabrina Beaulieu; Alain Larocque; Élie Besserer-Offroy; Karine Belleville; Karyn Kirby; Jean-Michel Longpré; Michel Demeule; Philippe Sarret
err分享
err收藏
Dual-target opioid/neurotensin ligands drive potent and safer analgesia in vivo双靶点阿片类/神经tensin配体在体内驱动强效且更安全的镇痛作用
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2026-05-11
err0
errOAAI
errÉmile Breault; Jolien De Neve; Amirmohammad Ranjbaran; Alexandre Tremblay; Ines Robberechts; Frédérique Lussier; Félix Bélair; Victoria Tremblay; Brian J. Holleran; Isabelle Brochu; Nicolò Bisi; Jérôme Côté; Jean-Michel Longpré; Louis Gendron; Steven Ballet; Philippe Sarret
err分享
err收藏
A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function神经tensin受体1型衍生的pepducin作为偏向性别构调节剂来调节靶受体的功能
errActa Pharmaceutica Sinica B
IF14.6
err2025-12-30
err0
errOAAI
errRebecca L. Brouillette; Frédérique Lussier; Émile Breault; Nathan Meneboo; Malihe Hassanzadeh; Victoria Tremblay; Magali Chartier; Élora Midavaine; Laurence Ulrich; Jérôme Côté; Véronique Blais; Christine E. Mona; Jean-Michel Longpré; Michel Grandbois; Pierre-Luc Boudreault; Martin Audet; Élie Besserer-Offroy; Philippe Sarret
err分享
err收藏
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors基于结构的环肽设计以生成靶向G蛋白偶联受体的功能性抗体
errNature Communications
IF15.7
err2025-12-12
err0
errOAAI
errMarie-Edith Nepveu-Traversy; Malihe Hassanzadeh; Laurent Bruneau-Cossette; Élie Besserer-Offroy; Rebecca Brouillette; Sandra Morissette; Hassan Traboulsi; Karyn Kirby; Alexandre Murza; Jean-Michel Longpré; Billy Breton; Fernand-Pierre Gendron; Simon Gaudreau; Pierre-Luc Boudreault; Philippe Sarret
err分享
err收藏
Spotlight on Endocannabinoids in Healthy Individuals Using Volumetric Absorptive Microsampling Combined with LC-MS/MS Analysis聚焦健康个体内源性大麻素的研究：采用容积吸收微采血技术结合LC-MS/MS分析
errACS Omega
IF4.3
err2025-11-06
err0
errOAAI
errLounes Haroune; Sabrina Saibi; Jean-Philippe Bellenger; Matthieu Vincenot; Guillaume Léonard; Louis Gendron; Philippe Sarret
err分享
err收藏
Structure-activity relationships of contulakin-G: Design, synthesis, and characterization of Thr10 analogs for pain modulationContulakin-G的结构-活性关系：用于疼痛调控的Thr10类似物的设计、合成与表征
errBiomedicine & Pharmacotherapy
IF7.5
err2025-10-22
err0
errOAAI
errAnnik Lanoie; Sára Ferková; Édouard Caron-Duval; Juliana C.C. Dallagnol; Sitan Diarra; Alexandre Murza; Alexandre Tremblay; Léa Théroux; Émile Breault; Amirmohammad Ranjbaran; Léa Landry; Jérôme Côté; Jean-Michel Longpré; Pierre-Luc Boudreault; David Chatenet; Philippe Sarret
err分享
err收藏
Opioid Analgesics: Rise and Fall of Ligand Biased Signaling and Future Perspectives in the Quest for the Holy Grail阿片类镇痛药：配体偏向性信号传导的兴衰及对寻找圣杯的追求中的未来展望
errCNS DRUGS
IF7.4
err2025-04-01
err0
PREAI
errBreault, Emile; Brouillette, Rebecca L.; Hebert, Terence E.; Sarret, Philippe; Besserer-Offroy, Elie
err分享
err收藏
Multitarget ligands that comprise opioid/nonopioid pharmacophores for pain management: Current state of the science
errPHARMACOLOGICAL RESEARCH
IF10.5
err2024-11-01
err0
errOAAI
errBreault, Emile; Desgagne, Michael; De Neve, Jolien; Cote, Jerome; Barlow, Thomas M. A.; Ballet, Steven; Sarret, Philippe
err分享
err收藏
Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid-Free Analgesics
errANGEWANDTE CHEMIE-INTERNATIONAL EDITION
IF16.9
err2024-10-14
err0
PREAI
errDesgagne, Michael; Chartier, Magali; Lagard, Camille; Ferkova, Sara; Choquette, Mathieu; Longpre, Jean-Michel; Cote, Jerome; Boudreault, Pierre-Luc; Sarret, Philippe
err分享
err收藏
Plasma Endocannabinoids Are Independently Associated With the Metabolic Function of White Adipose Tissue
errJOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
err2024-09-19
err0
errOAAI
errDion, Dany; Noll, Christophe; Fortin, Melanie; Haroune, Lounes; Saibi, Sabrina; Sarret, Philippe; Carpentier, Andre C.
err分享
err收藏
Rational In Silico Design of Selective TMPRSS6 Peptidomimetic Inhibitors via Exploitation of the S2 Subpocket
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-07-19
err0
PREAI
errDesgagne, Michael; Desilets, Antoine; Ferkova, Sara; Lepage, Matthieu; Perreault, Olivier; Joushomme, Alexandre; Lemieux, Gabriel; Guerrab, Walid; Froehlich, Ulrike; Comeau, Christian; Sarret, Philippe; Leduc, Richard; Boudreault, Pierre-Luc
err分享
err收藏
Discovery of a CCR2-targeting pepducin therapy for chronic pain
errPHARMACOLOGICAL RESEARCH
IF10.5
err2024-07-01
err0
errOAAI
errMidavaine, Elora; Brouillette, Rebecca L.; Theberge, Elizabeth; Mona, Christine E.; Kashem, Sakeen W.; Cote, Jerome; Zeugin, Vera; Besserer-Offroy, Elie; Longpre, Jean-Michel; Marsault, Eric; Sarret, Philippe
err分享
err收藏
Dopamine-sensitive neurons in the mesencephalic locomotor region control locomotion initiation, stop, and turns
errCELL REPORTS
IF6.9
err2024-05-01
err1
errOAAI
errTello, Andrea Juarez; van der Zouwen, Cornelis Immanuel; Dejas, Leonie; Duque-Yate, Juan; Boutin, Joel; Medina-Ortiz, Katherine; Suresh, Jacinthlyn Sylvia; Swiegers, Jordan; Sarret, Philippe; Ryczko, Dimitri
err分享
err收藏
Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice
errSCIENCE TRANSLATIONAL MEDICINE
IF14.6
err2024-03-20
err1
PREAI
errLe Moal, Emmeran; Liu, Yuguo; Collerette-Tremblay, Jasmin; Dumontier, Simon; Fabre, Paul; Molina, Thomas; Dort, Junio; Orfi, Zakaria; Denault, Nicolas; Boutin, Joel; Michaud, Joris; Giguere, Hugo; Desroches, Alexandre; Tran, Kien; Ellezam, Benjamin; Vezina, Francois; Bedard, Sonia; Raynaud, Catherine; Balg, Frederic; Sarret, Philippe; Boudreault, Pierre-Luc; Scott, Michelle S.; Denault, Jean-Bernard; Marsault, Eric; Feige, Jerome N.; Auger-Messier, Mannix; Dumont, Nicolas A.; Bentzinger, C. Florian
err分享
err收藏
Structural insight into apelin receptor-G protein stoichiometry
errNATURE STRUCTURAL & MOLECULAR BIOLOGY
IF10.1
err2022-07-11
err24
PREAI
errYue, Yang; Liu, Lier; Wu, Li-Jie; Wu, Yiran; Wang, Ling; Li, Fei; Liu, Junlin; Han, Gye-Won; Chen, Bo; Lin, Xi; Brouillette, Rebecca L.; Breault, Emile; Longpre, Jean-Michel; Shi, Songting; Lei, Hui; Sarret, Philippe; Stevens, Raymond C.; Hanson, Michael A.; Xu, Fei
err分享
err收藏
Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2022-01-04
err8
PREAI
errTran, Kien; Sainsily, Xavier; Cote, Jerome; Coquerel, David; Couvineau, Pierre; Saibi, Sabrina; Haroune, Lounes; Besserer-Offroy, Elie; Flynn-Robitaille, Joel; Rojas, Martin Resua; Murza, Alexandre; Longpre, Jean-Michel; Auger-Messier, Mannix; Lesur, Olivier; Bouvier, Michel; Marsault, Eric; Boudreault, Pierre-Luc; Sarret, Philippe
err分享
err收藏
Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients
errSCIENTIFIC REPORTS
IF3.9
err2021-11-23
err8
errOAAI
errCoquerel, David; Lamoureux, Julie; Chagnon, Frederic; Tran, Kien; Sage, Michael; Fortin-Pellerin, Etienne; Delile, Eugenie; Sainsily, Xavier; Fournier, Justin; Dumont, Audrey-Ann; Auger-Messier, Mannix; Sarret, Philippe; Marsault, Eric; Praud, Jean-Paul; Fulop, Tamas; Lesur, Olivier
err分享
err收藏
Optogenetic stimulation of glutamatergic neurons in the cuneiform nucleus controls locomotion in a mouse model of Parkinson's disease楔形核中谷氨酸能神经元的光遗传刺激可控制帕金森氏病小鼠模型的运动
errPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
err2021-10-20
err39
errOAAI
errFougere, Maxime; van der Zouwen, Cornelis Immanuel; Boutin, Joel; Neszvecsko, Kloe; Sarret, Philippe; Ryczko, Dimitri
err分享
err收藏
Pharmacodynamic and pharmacokinetic profiles of a neurotensin receptor type 2 (NTS2) analgesic macrocyclic analog
errBIOMEDICINE & PHARMACOTHERAPY
IF7.5
err2021-09-01
err8
errOAAI
errChartier, Magali; Desgagne, Michael; Sousbie, Marc; Rumsby, Charles; Chevillard, Lucie; Theroux, Lea; Haroune, Lounes; Cote, Jerome; Longpre, Jean-Michel; Boudreault, Pierre-Luc; Marsault, Eric; Sarret, Philippe
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
R
Raymond C. Stevens
H 指数: 127 · 论文数: 651
K
Klaus H. Kaestner
H 指数: 126 · 论文数: 604
C
Charles Antzelevitch
H 指数: 125 · 论文数: 860
A
Andreas Plückthun
H 指数: 112 · 论文数: 724
M
Michel Bouvier
H 指数: 108 · 论文数: 808
查看更多