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M

Mannix Auger-Messier

University of Sherbrooke

H指数:25

被引数:2,301

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A Metabolically Stable Apelin-13 Analog Acting as a Potent ITo Potassium Current Blocker with Potential Benefits for Brugada Syndrome

一种代谢稳定性Apelin-13类似物，可作为强效ITo钾电流阻滞剂，对Brugada综合征具有潜在益处

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-03-180

OA

Apelin stimulation of the vascular skeletal muscle stem cell niche enhances endogenous repair in dystrophic mice

SCIENCE TRANSLATIONAL MEDICINE

IF14.6

2024-03-201

PRE

Le Moal, Emmeran; Liu, Yuguo; Collerette-Tremblay, Jasmin; Dumontier, Simon; Fabre, Paul; Molina, Thomas; Dort, Junio; Orfi, Zakaria; Denault, Nicolas; Boutin, Joel; Michaud, Joris; Giguere, Hugo; Desroches, Alexandre; Tran, Kien; Ellezam, Benjamin; Vezina, Francois; Bedard, Sonia; Raynaud, Catherine; Balg, Frederic; Sarret, Philippe; Boudreault, Pierre-Luc; Scott, Michelle S.; Denault, Jean-Bernard; Marsault, Eric; Feige, Jerome N.; Auger-Messier, Mannix; Dumont, Nicolas A.; Bentzinger, C. Florian

Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model

JOURNAL OF THE AMERICAN HEART ASSOCIATION

IF5.3

2023-02-217

OAAI

Size-Reduced Macrocyclic Analogues of [Pyr1]-apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2022-01-048

PRE

Apelin-13 in septic shock: effective in supporting hemodynamics in sheep but compromised by enzymatic breakdown in patients

SCIENTIFIC REPORTS

IF3.9

2021-11-238

OAAI

Cardiomyocyte-specific Srsf3 deletion reveals a mitochondrial regulatory role

IF4.2

2021-04-054

OA

Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2021-02-0111

OA

Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2020-12-228

PREAI

The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders

apelinergic系统: 对心血管和代谢紊乱的挑战和机遇的看法

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

IF4.8

2019-06-2545

OAAI

Diabetes-Induced DUSP4 Reduction Promotes Podocyte Dysfunction and Progression of Diabetic Nephropathy

IF7.5

2019-03-1237

OAAI

ADAP1 limits neonatal cardiomyocyte hypertrophy by reducing integrin cell surface expression

SCIENTIFIC REPORTS

IF3.9

2018-09-1110

OAAI

The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment

PHARMACOLOGICAL RESEARCH

IF10.5

2018-05-0124

OAAI

A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2018-02-2030

PREAI

The apelinergic system as an alternative to catecholamines in low-output septic shock

IF9.3

2018-01-1919

OAAI

ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock

ELABELA可改善致命的实验性败血症休克的心肾结局

CRITICAL CARE MEDICINE

IF6

2017-11-0154

PREAI

Apelin Compared With Dobutamine Exerts Cardioprotection and Extends Survival in a Rat Model of Endotoxin-Induced Myocardial Dysfunction

CRITICAL CARE MEDICINE

IF6

2017-04-0134

PREAI

Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2016-03-30111

PREAI

C-Terminal Modifications of Apelin-13 Significantly Change Ligand Binding, Receptor Signaling, and Hypotensive Action

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2015-02-2448

PREAI

Unrestrained p38 MAPK Activation in Dusp1/4 Double-Null Mice Induces Cardiomyopathy

CIRCULATION RESEARCH

IF16.2

2013-01-0494

OAAI

Interaction Between NFκB and NFAT Coordinates Cardiac Hypertrophy and Pathological Remodeling

CIRCULATION RESEARCH

IF16.2

2012-04-13165

OAAI