未登录 Pharmacodynamic activity of BMS-986156, a glucocorticoid-induced TNF receptor-related protein agonist, alone or in combination with nivolumab in patients with advanced solid tumors Wang, R.; Baxi, V.; Li, Z.; Locke, D.; Hedvat, C.; Sun, Y.; Walsh, A. M.; Shao, X.; Basavanhally, T.; Greenawalt, D. M.; Patah, P.; Novosiadly, R. 分享 收藏
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MACHINE LEARNING MODELS CAN QUANTIFY CD8 POSITIVITY IN LYMPHOCYTES IN MELANOMA CLINICAL TRIAL SAMPLES Glass, Benjamin; Stanford-Moore, S. Adam; Meghwal, Diksha; Agrawal, Nishant; Lin, Mary; Hedvat, Cyrus; Lee, George; Ely, Scott; Montalto, Michael; Wapinski, Ilan; Baxi, Vipul; Beck, Andrew 分享 收藏
Tumor intrinsic properties associate with differential effects on CD8+tumor-infiltrating lymphocyte density and immune gene expression in non-small cell lung cancer (NSCLC) samples Hedvat, Cyrus; Desai, Keyur; Pandya, Dimple; Szabo, Peter; Zimmermann, Johannes; Lesniak, Jan; Ely, Scott; Srinivasan, Sujaya; Wang, Xi-Tao; French, Michele; Edwards, Robin 分享 收藏
Preliminary phase 1 profile of BMS-986179, an anti-CD73 antibody, in combination with nivolumab in patients with advanced solid tumors Siu, Lillian L.; Burris, Howard; Le, Dung T.; Hollebecque, Antoine; Steeghs, Neeltje; Delord, Jean-Pierre; Hilton, John; Barnhart, Bryan; Sega, Emanuela; Sanghavi, Kinjal; Klippel, Anke; Hedvat, Cyrus; Hilt, Ed; Donovan, Mark; Gipson, Adrianna; Basciano, Paul; Postelnek, Jennifer; Zhao, Yue; Perez, Raymond P.; Carvajal, Richard D. 分享 收藏
Detection of Mutations in Myeloid Malignancies through Paired-Sample Analysis of Microdroplet-PCR Deep Sequencing Data Cheng, Donavan T.; Cheng, Janice; Mitchell, Talia N.; Syed, Aijazuddin; Zehir, Ahmet; Mensah, Nana Yaa T.; Oultache, Alifya; Nafa, Khedoudja; Levine, Ross L.; Arcila, Maria E.; Berger, Michael. F.; Hedvat, Cyrus V. 分享 收藏
Effect of Selumetinib vs Chemotherapy on Progression-Free Survival in Uveal Melanoma A Randomized Clinical Trial Carvajal, Richard D.; Sosman, Jeffrey A.; Quevedo, Jorge Fernando; Milhem, Mohammed M.; Joshua, Anthony M.; Kudchadkar, Ragini R.; Linette, Gerald P.; Gajewski, Thomas F.; Lutzky, Jose; Lawson, David H.; Lao, Christopher D.; Flynn, Patrick J.; Albertini, Mark R.; Sato, Takami; Lewis, Karl; Doyle, Austin; Ancell, Kristin; Panageas, Katherine S.; Bluth, Mark; Hedvat, Cyrus; Erinjeri, Joseph; Ambrosini, Grazia; Marr, Brian; Abramson, David H.; Dickson, Mark Andrew; Wolchok, Jedd D.; Chapman, Paul B.; Schwartz, Gary K. 分享 收藏
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Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing 基于大规模平行DNA测序的临床癌症基因组分析测试的开发和验证 Frampton, Garrett M.; Fichtenholtz, Alex; Otto, Geoff A.; Wang, Kai; Downing, Sean R.; He, Jie; Schnall-Levin, Michael; White, Jared; Sanford, Eric M.; An, Peter; Sun, James; Juhn, Frank; Brennan, Kristina; Iwanik, Kiel; Maillet, Ashley; Buell, Jamie; White, Emily; Zhao, Mandy; Balasubramanian, Sohail; Terzic, Selmira; Richards, Tina; Banning, Vera; Garcia, Lazaro; Mahoney, Kristen; Zwirko, Zac; Donahue, Amy; Beltran, Himisha; Mosquera, Juan Miguel; Rubin, Mark A.; Dogan, Snjezana; Hedvat, Cyrus V.; Berger, Michael F.; Pusztai, Lajos; Lechner, Matthias; Boshoff, Chris; Jarosz, Mirna; Vietz, Christine; Parker, Alex; Miller, Vincent A.; Ross, Jeffrey S.; Curran, John; Cronin, Maureen T.; Stephens, Philip J.; Lipson, Doron; Yelensky, Roman 分享 收藏
CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia CD19-Targeted T细胞快速诱导化疗难治性急性淋巴细胞白血病成人的分子缓解 Brentjens, Renier J.; Davila, Marco L.; Riviere, Isabelle; Park, Jae; Wang, Xiuyan; Cowell, Lindsay G.; Bartido, Shirley; Stefanski, Jolanta; Taylor, Clare; Olszewska, Malgorzata; Borquez-Ojeda, Oriana; Qu, Jinrong; Wasielewska, Teresa; He, Qing; Bernal, Yvette; Rijo, Ivelise V.; Hedvat, Cyrus; Kobos, Rachel; Curran, Kevin; Steinherz, Peter; Jurcic, Joseph; Rosenblat, Todd; Maslak, Peter; Frattini, Mark; Sadelain, Michel 分享 收藏
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CANCER Akt Phosphorylates the Transcriptional Repressor Bmi1 to Block Its Effects on the Tumor-Suppressing Ink4a-Arf Locus Liu, Yan; Liu, Fan; Yu, Hao; Zhao, Xinyang; Sashida, Goro; Deblasio, Anthony; Harr, Michael; She, Qing-Bai; Chen, Zhenbang; Lin, Hui-Kuan; Di Giandomenico, Silvana; Elf, Shannon E.; Yang, Youyang; Miyata, Yasuhiko; Huang, Gang; Menendez, Silvia; Mellinghoff, Ingo K.; Rosen, Neal; Pandolfi, Pier Paolo; Hedvat, Cyrus V.; Nimer, Stephen D. 分享 收藏
Regulatory T Cell Infiltration Predicts Outcome Following Resection of Colorectal Cancer Liver Metastases Katz, Steven C.; Bamboat, Zubin M.; Maker, Ajay V.; Shia, Jinru; Pillarisetty, Venu G.; Yopp, Adam C.; Hedvat, Cyrus V.; Gonen, Mithat; Jarnagin, William R.; Fong, Yuman; D'Angelica, Michael I.; DeMatteo, Ronald P. 分享 收藏
Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice Xiong, X.; Chorzalska, A.; Dubielecka, P. M.; White, J. R.; Vedvyas, Y.; Hedvat, C. V.; Haimovitz-Friedman, A.; Koutcher, J. A.; Reimand, J.; Bader, G. D.; Sawicki, J. A.; Kotula, L. 分享 收藏
Massively parallel sequencing of cancer FFPE specimens matches diagnostic accuracy of methods in current clinical use and reveals additional actionable mutations Yelensky, Roman; Dogan, Snjezana; Borsu, Laetitia; Frampton, Garrett; Lipson, Doron; Bastian, Boris C.; Klimstra, David S.; Ladanyi, Marc; Cronin, Maureen; Hedvat, Cyrus V.; Berger, Michael F. 分享 收藏
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PHF6 mutations in adult acute myeloid leukemia Van Vlierberghe, P.; Patel, J.; Abdel-Wahab, O.; Lobry, C.; Hedvat, C. V.; Balbin, M.; Nicolas, C.; Payer, A. R.; Fernandez, H. F.; Tallman, M. S.; Paietta, E.; Melnick, A.; Vandenberghe, P.; Speleman, F.; Aifantis, I.; Cools, J.; Levine, R.; Ferrando, A. 分享 收藏
HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans Marubayashi, Sachie; Koppikar, Priya; Taldone, Tony; Abdel-Wahab, Omar; West, Nathan; Bhagwat, Neha; Caldas-Lopes, Eloisi; Ross, Kenneth N.; Goenen, Mithat; Gozman, Alex; Ahn, James H.; Rodina, Anna; Ouerfelli, Ouathek; Yang, Guangbin; Hedvat, Cyrus; Bradner, James E.; Chiosis, Gabriela; Levine, Ross L. 分享 收藏