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收藏Transcriptomics profiling of the non-small cell lung cancer microenvironment across disease stages reveals dual immune cell-type behaviors
Hurtado, Marcelo; Khajavi, Leila; Essabbar, Abdelmounim; Kammer, Michael; Xie, Ting; Coullomb, Alexis; Pradines, Anne; Casanova, Anne; Kruczynski, Anna; Gouin, Sandrine; Clermont, Estelle; Boutillet, Lea; Senosain, Maria Fernanda; Zou, Yong; Zhao, Shillin; Burq, Prosper; Mahfoudi, Abderrahim; Besse, Jerome; Launay, Pierre; Passioukov, Alexandre; Chetaille, Eric; Favre, Gilles; Maldonado, Fabien; Cruzalegui, Francisco; Delfour, Olivier; Mazieres, Julien; Pancaldi, Vera
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收藏Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies
Figarol, Sarah; Delahaye, Celia; Gence, Remi; Doussine, Aurelia; Cerapio, Juan Pablo; Brachais, Mathylda; Tardy, Claudine; Bery, Nicolas; Asslan, Raghda; Colinge, Jacques; Villemin, Jean-Philippe; Maraver, Antonio; Ferrer, Irene; Paz-Ares, Luis; Kessler, Linda; Burrows, Francis; Lajoie-Mazenc, Isabelle; Dongay, Vincent; Morin, Clara; Florent, Amelie; Pagano, Sandra; Taranchon-Clermont, Estelle; Casanova, Anne; Pradines, Anne; Mazieres, Julien; Favre, Gilles; Calvayrac, Olivier
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收藏TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks
Geraud, Mathea; Cristini, Agnese; Salimbeni, Simona; Bery, Nicolas; Jouffret, Virginie; Russo, Marco; Ajello, Andrea Carla; Martinez, Lara Fernandez; Marinello, Jessica; Cordelier, Pierre; Trouche, Didier; Favre, Gilles; Nicolas, Estelle; Capranico, Giovanni; Sordet, Olivier
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收藏Assessment of minimal residual disease in lung cancer patients treated with osimertinib using liquid biopsy
Delahaye, Celia; Casanova, Anne; Clermont-Tarenchon, Estelle; Doussine, Aurelia; Cerapio, Juan-Pablo; Anton, Anais; Devienne, Emma; Dongay, Vincent; Milia, Julie; Favre, Gilles; Calvayrac, Olivier; Pradines, Anne; Mazieres, Julien
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收藏Productive HIV-1 infection of tissue macrophages by fusion with infected CD4+ T cells
Mascarau, Remi; Woottum, Marie; Fromont, Lea; Gence, Remi; Cantaloube-Ferrieu, Vincent; Vahlas, Zoi; Leveque, Kevin; Bertrand, Florent; Beunon, Thomas; Metais, Arnaud; El Costa, Hicham; Jabrane-Ferrat, Nabila; Gallois, Yohan; Guibert, Nicolas; Davignon, Jean-Luc; Favre, Gilles; Maridonneau-Parini, Isabelle; Poincloux, Renaud; Lagane, Bernard; Benichou, Serge; Raynaud-Messina, Brigitte; Verollet, Christel
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收藏Epigenetically regulated PCDHB15 impairs aggressiveness of metastatic melanoma cells
Carrier, Arnaud; Desjobert, Cecile; Lobjois, Valerie; Rigal, Lise; Busato, Florence; Tost, Jorg; Ensenyat-Mendez, Miquel; Marzese, Diego M.; Pradines, Anne; Favre, Gilles; Lamant, Laurence; Lanfrancone, Luisa; Etievant, Chantal; Arimondo, Paola B.; Riond, Joelle
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收藏DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness
Carrier, Arnaud; Desjobert, Cecile; Ponger, Loic; Lamant, Laurence; Bustos, Matias; Torres-Ferreira, Jorge; Henrique, Rui; Jeronimo, Carmen; Lanfrancone, Luisa; Delmas, Audrey; Favre, Gilles; Daunay, Antoine; Busato, Florence; Hoon, Dave S. B.; Tost, Jorg; Etievant, Chantal; Riond, Joelle; Arimondo, Paola B.
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收藏Tripartite split-GFP assay to identify selective intracellular nanobody that suppresses GTPase RHOA subfamily downstream signaling
Keller, Laura; Tardy, Claudine; Ligat, Laetitia; Le Pennec, Soazig; Bery, Nicolas; Koraichi, Faten; Chinestra, Patrick; David, Melissa; Gence, Remi; Favre, Gilles; Cabantous, Stephanie; Olichon, Aurelien
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收藏Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer
Keller, Laura; Tardy, Claudine; Ligat, Laetitia; Gilhodes, Julia; Filleron, Thomas; Bery, Nicolas; Rochaix, Philippe; Aquilina, Alexis; Bdioui, Sara; Roux, Thomas; Trinquet, Eric; Favre, Gilles; Olichon, Aurelien
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收藏Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma在EGFR驱动的肺腺癌中,Notch抑制克服了对酪氨酸激酶抑制剂的抗性
Mur, Emilie Bousquet; Bernardo, Sara; Papon, Laura; Mancini, Maicol; Fabbrizio, Eric; Goussard, Marion; Ferrer, Irene; Giry, Anais; Quantin, Xavier; Pujol, Jean-Louis; Calvayrac, Olivier; Moll, Herwig P.; Glasson, Yael; Pirot, Nelly; Turtoi, Andrei; Canamero, Marta; Wong, Kwok-Kin; Yarden, Yosef; Casanova, Emilio; Soria, Jean-Charles; Colinge, Jacques; Siebel, Christian W.; Mazieres, Julien; Favre, Gilles; Paz-Ares, Luis; Maraver, Antonio
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收藏A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation
Bery, Nicolas; Keller, Laura; Soulie, Marjorie; Gence, Remi; Iscache, Anne-Laure; Cherier, Julia; Cabantous, Stephanie; Sordet, Olivier; Lajoie-Mazenc, Isabelle; Pedelacq, Jean-Denis; Favre, Gilles; Olichon, Aurelien
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收藏Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand BreaksR环和拓扑异构酶I的双重加工诱导转录依赖性DNA双链断裂
Cristini, Agnese; Ricci, Giulia; Britton, Sebastien; Salimbeni, Simona; Huang, Shar-yin Naomi; Marinello, Jessica; Calsou, Patrick; Pommier, Yves; Favre, Gilles; Capranico, Giovanni; Gromak, Natalia; Sordet, Olivier
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