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M

Masami Otsuka

kumamoto university

33H指数
271论文数
4.3K被引数
收录论文 75
发表时间
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Harnessing Substituted 4-Chlorothieno[2,3-b]pyridine as a New Cap for Potent and Selective Antiproliferative HDAC Inhibitors利用4-氯噻吩并[2,3-b]吡啶衍生物作为新型帽基，开发高效且高选择性的抗增殖HDAC抑制剂
errPharmaceuticals
IF4.8
err2026-03-10
err0
errOAAI
errMostafa M. Badran; Berkay Beyri; Hiroshi Tateishi; Kazunori Shimagaki; Akiko Nakata; Akihiro Ito; Nao Nishimura; Samar H. Abbas; Mohamed Abdel-Aziz; Masami Otsuka; Minoru Yoshida; Mikako Fujita; Stefan Bräse; Mohamed O. Radwan
err分享
err收藏
Hydrazonylthiazole Derivatives as Dual EGFR and ALR2 Inhibitors: Design, Synthesis, and Comprehensive In Vitro and In Silico Evaluation for Potential Anticancer Activity肼基噻唑衍生物作为EGFR和ALR2双重抑制剂：设计、合成及潜在抗肿瘤活性的全面体外和计算机模拟评价
errPharmaceuticals
IF4.8
err2026-03-04
err0
errOAAI
errBelgin Sever; Cüneyt Türkeş; Yeliz Demir; Khaled M. Elamin; Wadah Osman; Kübra Oral; Selenay Akıncı Genç; Zerrin Cantürk; Takuya Masunaga; Naoki Kishimoto; Shogo Misumi; Masami Otsuka; Mikako Fujita; Halilibrahim Ciftci
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An anti-cell migration compound that binds to hnRNP U and suppresses nuclear deformation一种与hnRNP U结合并抑制核变形的抗细胞迁移化合物
errBIOORGANIC CHEMISTRY
IF4.7
err2025-03-01
err0
PREAI
errToma, Tsugumasa; Nakahara, Ryosei; Otsuka, Masami; Fujita, Mikako; Tateishi, Hiroshi
err分享
err收藏
An antifibrotic compound that ameliorates hyperglycaemia and fat accumulation in cell and HFD mouse models
errDIABETOLOGIA
IF10.2
err2024-09-09
err0
PREAI
errToma, Tsugumasa; Miyakawa, Nobukazu; Arakaki, Yuiichi; Watanabe, Takuro; Nakahara, Ryosei; Ali, Taha F. S.; Biswas, Tanima; Todaka, Mikio; Kondo, Tatsuya; Fujita, Mikako; Otsuka, Masami; Araki, Eiichi; Tateishi, Hiroshi
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A heterocyclic compound inhibits viral release by inducing cell surface BST2/Tetherin/CD317/HM1.24
errJOURNAL OF BIOLOGICAL CHEMISTRY
IF3.9
err2024-09-01
err0
errOAAI
errNyame, Perpetual; Togami, Akihiro; Yoshida, Tomofumi; Masunaga, Takuya; Begum, Monira; Terasawa, Hiromi; Monde, Nami; Tahara, Yurika; Tanaka, Reiko; Tanaka, Yuetsu; Appiah-Kubi, Joyce; Amesimeku, Wright Andrews Ofotsu; Hossain, Md Jakir; Otsuka, Masami; Yoshimura, Kazuhisa; Ikeda, Terumasa; Sawa, Tomohiro; Satou, Yorifumi; Fujita, Mikako; Maeda, Yosuke; Tateishi, Hiroshi; Monde, Kazuaki
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Ligand-based design and synthesis of new trityl histamine and trityl cysteamine derivatives as SIRT2 inhibitors for cancer therapy基于配体的新型三苯甲基组胺和三苯甲基半胱胺衍生物的设计与合成，作为SIRT2抑制剂用于癌症治疗
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2024-04-01
err3
PREAI
errBadran, Mostafa M.; Abbas, Samar H.; Tateishi, Hiroshi; Maemoto, Yuki; Toma, Tsugumasa; Ito, Akihiro; Fujita, Mikako; Otsuka, Masami; Abdel-Aziz, Mohamed; Radwan, Mohamed O.
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Design and synthesis of new quinoline-ester/-amide derivatives as potent antiproliferative agent targeting EGFR and BRAFV600E kinases
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2024-02-01
err7
PREAI
errMohassab, Aliaa M.; Hassan, Heba A.; Abou-Zied, Hesham A.; Fujita, Mikako; Otsuka, Masami; Gomaa, Hesham A. M.; Youssif, Bahaa G. M.; Abdel-Aziz, Mohamed
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An ADAM17 selective inhibitor promotes glucose uptake by activating AMPK
errJOURNAL OF PHARMACOLOGICAL SCIENCES
IF2.9
err2024-01-01
err2
errOAAI
errToma, Tsugumasa; Miyakawa, Nobukazu; Tateishi, Mika; Todaka, Mikio; Kondo, Tatsuya; Fujita, Mikako; Otsuka, Masami; Araki, Eiichi; Tateishi, Hiroshi
err分享
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Scaffold Hopping and Structural Modification of NSC 663284: Discovery of Potent (Non)Halogenated Aminobenzoquinones
errBIOMEDICINES
IF3.9
err2023-12-24
err1
errOAAI
errBayrak, Niluefer; Sever, Belgin; Ciftci, Halilibrahim; Otsuka, Masami; Fujita, Mikako; Tuyun, Amac Fatih
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HIV-1 Gag MA domain binds to cardiolipin in a binding mode distinct from virus assemble mediator PI(4,5)P2
errCHEMICAL BIOLOGY & DRUG DESIGN
IF3.3
err2023-11-20
err0
PREAI
errTateishi, Hiroshi; Chinen, Takuma; Fukuda, Ryota; Radwan, Mohamed O.; Shimagaki, Kazunori; Koga, Ryoko; Masuda, Takashi; Okamoto, Yoshinari; Sakamoto, Arisa; Misumi, Shogo; Otsuka, Masami; Fujita, Mikako; Anraku, Kensaku
err分享
err收藏
Structural Characterization of TRAF6 N-Terminal for Therapeutic Uses and Computational Studies on New Derivatives
errPHARMACEUTICALS
IF4.8
err2023-11-14
err3
errOAAI
errGuven, Omur; Sever, Belgin; Basoglu-Unal, Faika; Ece, Abdulilah; Tateishi, Hiroshi; Koga, Ryoko; Radwan, Mohamed O.; Demir, Nefise; Can, Mustafa; Aytemir, Mutlu Dilsiz; Inoue, Jun-ichiro; Otsuka, Masami; Fujita, Mikako; Ciftci, Halilibrahim; Demirci, Hasan
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The unique activity of saponin: Induction of cytotoxicity in HTLV-1 infected cells
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2023-08-01
err2
PREAI
errShida, Wataru; Tahara, Yurika; Morikawa, Saki; Monde, Kazuaki; Koga, Ryoko; Ohsugi, Takeo; Otsuka, Masami; Ikemoto, Atsushi; Tateishi, Hiroshi; Ikeda, Tsuyoshi; Fujita, Mikako
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Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes Game of Thrones on Anti-Cancer Therapy: A Critical Review-Dedicated to the Memory of Professor Hanaa M. Rady
errMOLECULES
IF4.6
err2023-07-27
err4
errOAAI
errRadwan, Mohamed O.; Abd-Alla, Howaida I.; Alsaggaf, Azhaar T.; El-Mezayen, Hatem; Abourehab, Mohammed A. S.; El-Beeh, Mohamed E.; Tateishi, Hiroshi; Otsuka, Masami; Fujita, Mikako
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Rapid and efficient ambient temperature X-ray crystal structure determination at Turkish Light Source
errSCIENTIFIC REPORTS
IF3.9
err2023-05-19
err3
errOAAI
errGul, Mehmet; Ayan, Esra; Destan, Ebru; Johnson, J. Austin; Shafiei, Alaleh; Kepceoglu, Abdullah; Yilmaz, Merve; Ertem, Fatma Betuel; Yapici, Ilkin; Tosun, Bilge; Baldir, Niluefer; Tokay, Nurettin; Nergiz, Zelis; Karakadioglu, Gozde; Paydos, Seyide Seda; Kulakman, Cahine; Ferah, Cengiz Kaan; Guven, Omur; Atalay, Necati; Akcan, Enver Kamil; Cetinok, Haluk; Arslan, Nazli Eylul; Sabanoglu, Kardelen; Asci, Bengisu; Tavli, Serra; Gumusboga, Helin; Altuntas, Sevde; Otsuka, Masami; Fujita, Mikako; Tekin, Saban; Ciftci, Halilibrahim; Durdagi, Serdar; Karaca, Ezgi; Turkoz, Burcu Kaplan; Kabasakal, Burak Veli; Kati, Ahmet; DeMirci, Hasan
err分享
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New insight into the bioactivity of substituted benzimidazole derivatives: Repurposing from anti-HIV activity to cell migration inhibition targeting hnRNP M
errBIOORGANIC & MEDICINAL CHEMISTRY
IF3
err2023-05-01
err9
PREAI
errRadwan, Mohamed O.; Toma, Tsugumasa; Arakaki, Yuiichi; Kamo, Masahiro; Inoue, Naoya; Koga, Ryoko; Otsuka, Masami; Tateishi, Hiroshi; Fujita, Mikako
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Design, synthesis, in vitro and in silico characterization of plastoquinone analogs containing piperidine moiety as antimicrobial agents
errJOURNAL OF MOLECULAR STRUCTURE
IF4.7
err2023-04-01
err6
PREAI
errYildiz, Mahmut; Yildirim, Hatice; Bayrak, Nilufer; Cakmak, Selin Melis; Mataraci-Kara, Emel; Ozbek-Celik, Berna; Otsuka, Masami; Fujita, Mikako; Radwan, Mohamed O.; TuYuN, Amac Fatih
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Studies on 1,4-Quinone Derivatives Exhibiting Anti-Leukemic Activity along with Anti-Colorectal and Anti-Breast Cancer Effects
errMOLECULES
IF4.6
err2022-12-22
err3
errOAAI
errCiftci, Halilibrahim; Sever, Belgin; Kaya, Nusret; Bayrak, Niluefer; Yildiz, Mahmut; Yildirim, Hatice; Tateishi, Hiroshi; Otsuka, Masami; Fujita, Mikako; TuYuN, Amac Fatih
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New Insights into the Structural Requirements of Isatin-Derived Pro-Apoptotic Agents against Acute Myeloid Leukemia
errPHARMACEUTICALS
IF4.8
err2022-12-17
err4
errOAAI
errHamdy, Ahmed K. K.; Sakamoto, Takashi; Toma, Tsugumasa; Sakamoto, Masaharu; Abourehab, Mohammed A. S.; Otsuka, Masami; Fujita, Mikako; Tateishi, Hiroshi; Radwan, Mohamed O. O.
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Difference in the Inhibitory Effect of Thiol Compounds and Demetallation Rates from the Zn(II) Active Site of Metallo-β-lactamases (IMP-1 and IMP-6) Associated with a Single Amino Acid Substitution
errACS INFECTIOUS DISEASES
IF3.8
err2022-12-15
err2
PREAI
errYamaguchi, Yoshihiro; Kato, Koichi; Ichimaru, Yoshimi; Uenosono, Yuya; Tawara, Sakiko; Ito, Rio; Matsuse, Natsuki; Wachino, Jun-ichi; Toma-Fukai, Sachiko; Jin, Wanchun; Arakawa, Yoshichika; Otsuka, Masami; Fujita, Mikako; Fukuishi, Nobuyuki; Sugiura, Kirara; Imai, Masanori; Kurosaki, Hiromasa
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In Vitro Cytotoxicity Evaluation of Plastoquinone Analogues against Colorectal and Breast Cancers along with In Silico Insights
errPHARMACEUTICALS
IF4.8
err2022-10-14
err11
errOAAI
errCiftci, Halilibrahim; Sever, Belgin; Bayrak, Nilufer; Yildiz, Mahmut; Yildirim, Hatice; Tateishi, Hiroshi; Otsuka, Masami; Fujita, Mikako; Tuyun, Amac Fatih
err分享
err收藏

研究方向

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