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Naoki Ishiguro

boehringer ingelheim pharma gmbh & co.kg

79H指数
1.1K论文数
2.8W被引数
收录论文 224
发表时间
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TRANSPORTER-TRANSPORTER INTERPLAY DETERMINES THE RENAL-PREDOMINANT ELIMINATION OF THE O-GLUCURONIDE METABOLITE (BI 689875) OF VICADROSTAT IN HUMANS转运体-转运体相互作用决定了维卡多司他（Vicadrostat）的O-葡萄糖醛酸代谢物（BI 689875）在人体中以肾脏为主的选择性消除。
errDrug Metabolism and Disposition
IF4
err2025-12-26
err0
PREAI
errPallabi Mitra; Rumanah Shah; Laeticia Iboki; Zachary Williams; Hlaing (Holly) Maw; Ting Wang; Matt Hrapchak; Bachir Latli; Raimund Kuelzer; Naoki Ishiguro; Ryo Takahashi; Takashi Kudo; Akiko Matsui; Mitchell E. Taub
err分享
err收藏
Advanced in vitro evaluation of drug-induced kidney injury using microphysiological systems in drug discovery and development利用微生理系统在药物发现与开发中对药物诱导的肾损伤进行高级体外评估
errDRUG METABOLISM AND PHARMACOKINETICS
IF2.2
err2025-02-01
err2
PREAI
errArakawa, Hiroshi; Matsushita, Kohei; Ishiguro, Naoki
err分享
err收藏
Three-dimensional culture of human proximal tubular epithelial cells for an in vitro evaluation of drug-induced kidney injury三维培养人近端肾小管上皮细胞体外评价药物性肾损伤
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2024-11-01
err2
errOAAI
errArakawa, Hiroshi; Higuchi, Daichi; Takahashi, Etsushi; Matsushita, Kohei; Nedachi, Shiho; Peng, Hanwei; Kadoguchi, Moeno; Morimura, Kaoru; Araki, Ayano; Kondo, Masayuki; Ishiguro, Naoki; Jimbo, Yoichi; Tamai, Ikumi
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Calcitriol ameliorates motor de fi cits and prolongs survival of Chrne-de fi cient mouse, a model for congenital myasthenic syndrome, by inducing Rspo2
errNEUROTHERAPEUTICS
IF6.9
err2024-03-01
err0
errOAAI
errOhkawara, Bisei; Tomita, Hiroyuki; Inoue, Taro; Zhang, Shaochuan; Kanbara, Shunsuke; Koshimizu, Hiroyuki; Miyasaka, Yuki; Takeda, Jun-ichi; Nishiwaki, Hiroshi; Nakashima, Hiroaki; Ito, Mikako; Masuda, Akio; Ishiguro, Naoki; Ogi, Tomoo; Ohno, Tamio; Imagama, Shiro; Ohno, Kinji
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Why does malaise/fatigue occur? Underlying mechanisms and potential relevance to treatments in rheumatoid arthritis为什么会出现不适/乏力？类风湿性关节炎的潜在作用机制及其对治疗的启示
errEXPERT REVIEW OF CLINICAL IMMUNOLOGY
IF3.7
err2024-01-19
err3
PREAI
errTanaka, Yoshiya; Ikeda, Kei; Kaneko, Yuko; Ishiguro, Naoki; Takeuchi, Tsutomu
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Gastrointestinal: A case of pancreatic gastrointestinal stromal tumor diagnosed by endoscopic ultrasound fine needle biopsy
errJOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
IF3.4
err2023-05-14
err0
errOAAI
errHirata, H.; Ishiguro, N.; Ito, K.; Suga, A.; Yasuura, N.; Egami, H.; Kobayashi, T.; Kato, T.
err分享
err收藏
Regional Differences in the Absolute Abundance of Transporters, Receptors and Tight Junction Molecules at the Blood-Arachnoid Barrier and Blood-Spinal Cord Barrier among Cervical, Thoracic and Lumbar Spines in Dogs
errPHARMACEUTICAL RESEARCH
IF4.3
err2022-04-29
err6
PREAI
errTakeuchi, Hina; Suzuki, Masayoshi; Goto, Ryohei; Tezuka, Kenta; Fuchs, Holger; Ishiguro, Naoki; Terasaki, Tetsuya; Braun, Clemens; Uchida, Yasuo
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Promethazine Downregulates Wnt/beta-Catenin Signaling and Increases the Biomechanical Forces of the Injured Achilles Tendon in the Early Stage of Healing异丙嗪下调Wnt/β-catenin信号通路并增加跟腱早期愈合的生物力学力
errAMERICAN JOURNAL OF SPORTS MEDICINE
IF4.5
err2022-03-02
err5
PREAI
errSakaguchi, Takefumi; Ohkawara, Bisei; Kishimoto, Yasuzumi; Miyamoto, Kentaro; Ishizuka, Shinya; Hiraiwa, Hideki; Ishiguro, Naoki; Imagama, Shiro; Ohno, Kinji
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Ischaemic skin ulcers with neurofibromatosis 1 successfully treated with stent implantation
errCLINICAL AND EXPERIMENTAL DERMATOLOGY
IF2.8
err2021-11-21
err0
PREAI
errSone, M.; Takenaka, Y.; Miyabe, C.; Suzuki, M.; Nakao, M.; Hagiwara, N.; Ishiguro, N.
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err收藏
Physiologically Based Pharmacokinetic Modeling of Rosuvastatin to Predict Transporter-Mediated Drug-Drug Interactions
errPHARMACEUTICAL RESEARCH
IF4.3
err2021-10-18
err15
errOAAI
errHanke, Nina; Gomez-Mantilla, Jose David; Ishiguro, Naoki; Stopfer, Peter; Nock, Valerie
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err收藏
Evaluation of Hepatic Uptake of OATP1B Substrates by Short Term-Cultured Plated Human Hepatocytes: Comparison With Isolated Suspended Hepatocytes
errJOURNAL OF PHARMACEUTICAL SCIENCES
IF3.8
err2021-01-01
err12
errOAAI
errYoshikado, Takashi; Lee, Wooin; Toshimoto, Kota; Morita, Kiyoe; Kiriake, Aya; Chu, Xiaoyan; Lee, Nora; Kimoto, Emi; Varma, Manthena V. S.; Kikuchi, Ryota; Scialis, Renato J.; Shen, Hong; Ishiguro, Naoki; Lotz, Ralf; Li, Albert P.; Maeda, Kazuya; Kusuhara, Hiroyuki; Sugiyama, Yuichi
err分享
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Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry
errSCIENTIFIC REPORTS
IF3.9
err2020-12-14
err20
errOAAI
errTakahashi, Nobunori; Asai, Shuji; Kobayakawa, Tomonori; Kaneko, Atsushi; Watanabe, Tatsuo; Kato, Takefumi; Nishiume, Tsuyoshi; Ishikawa, Hisato; Yoshioka, Yutaka; Kanayama, Yasuhide; Watanabe, Tsuyoshi; Hirano, Yuji; Hanabayashi, Masahiro; Yabe, Yuichiro; Yokota, Yutaka; Suzuki, Mochihito; Sobue, Yasumori; Terabe, Kenya; Ishiguro, Naoki; Kojima, Toshihisa
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Zonisamide ameliorates neuropathic pain partly by suppressing microglial activation in the spinal cord in a mouse model
errLIFE SCIENCES
IF5.1
err2020-12-01
err10
PREAI
errKoshimizu, Hiroyuki; Ohkawara, Bisei; Nakashima, Hiroaki; Ota, Kyotaro; Kanbara, Shunsuke; Inoue, Taro; Tomita, Hiroyuki; Sayo, Akira; Kiryu-Seo, Sumiko; Konishi, Hiroyuki; Ito, Mikako; Masuda, Akio; Ishiguro, Naoki; Imagama, Shiro; Kiyama, Hiroshi; Ohno, Kinji
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Predictors of disease flare after discontinuation of concomitant methotrexate in Japanese patients with rheumatoid arthritis treated with tocilizumab
errJOINT BONE SPINE
IF4.3
err2020-12-01
err7
errOAAI
errAsai, Shuji; Takahashi, Nobunori; Hayashi, Masatoshi; Hanabayashi, Masahiro; Kanayama, Yasuhide; Takemoto, Toki; Yabe, Yuichiro; Shioura, Tomone; Ishikawa, Hisato; Yoshioka, Yutaka; Kato, Takefumi; Hirano, Yuji; Fujibayashi, Takayoshi; Hattori, Yosuke; Kobayakawa, Tomonori; Ando, Masahiko; Kuwatsuka, Yachiyo; Matsumoto, Takuya; Asai, Nobuyuki; Sobue, Yasumori; Nishiume, Tsuyoshi; Suzuki, Mochihito; Ishiguro, Naoki; Kojima, Toshihisa
err分享
err收藏
A retrospective analysis of the relationship between anti-cyclic citrullinated peptide antibody and the effectiveness of abatacept in rheumatoid arthritis patients
errSCIENTIFIC REPORTS
IF3.9
err2020-11-12
err8
errOAAI
errKida, Daihei; Takahashi, Nobunori; Kaneko, Atsushi; Hirano, Yuji; Fujibayashi, Takayoshi; Kanayama, Yasuhide; Hanabayashi, Masahiro; Yabe, Yuichiro; Takagi, Hideki; Oguchi, Takeshi; Kato, Takefumi; Funahashi, Koji; Matsumoto, Takuya; Ando, Masahiko; Kuwatsuka, Yachiyo; Tanaka, Eiichi; Yasuoka, Hidekata; Kaneko, Yuko; Hirata, Shintaro; Murakami, Kosaku; Sobue, Yasumori; Nishiume, Tsuyoshi; Suzuki, Mochihito; Yokota, Yutaka; Terabe, Kenya; Asai, Shuji; Ishiguro, Naoki; Kojima, Toshihisa
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Zonisamide ameliorates progression of cervical spondylotic myelopathy in a rat model
errSCIENTIFIC REPORTS
IF3.9
err2020-08-04
err9
errOAAI
errKanbara, Shunsuke; Ohkawara, Bisei; Nakashima, Hiroaki; Ohta, Kyotaro; Koshimizu, Hiroyuki; Inoue, Taro; Tomita, Hiroyuki; Ito, Mikako; Masuda, Akio; Ishiguro, Naoki; Imagama, Shiro; Ohno, Kinji
err分享
err收藏
Low energy irradiation of narrow-range UV-LED prevents osteosarcopenia associated with vitamin D deficiency in senescence-accelerated mouse prone 6
errSCIENTIFIC REPORTS
IF3.9
err2020-07-17
err7
errOAAI
errMakida, Kazuya; Nishida, Yoshihiro; Morita, Daigo; Ochiai, Satoshi; Higuchi, Yoshitoshi; Seki, Taisuke; Ikuta, Kunihiro; Ishiguro, Naoki
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CTGF/CCN2 facilitates LRP4-mediated formation of the embryonic neuromuscular junction
errEMBO REPORTS
IF6.2
err2020-06-17
err16
errOAAI
errOhkawara, Bisei; Kobayakawa, Akinori; Kanbara, Shunsuke; Hattori, Takako; Kubota, Satoshi; Ito, Mikako; Masuda, Akio; Takigawa, Masaharu; Lyons, Karen M.; Ishiguro, Naoki; Ohno, Kinji
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Curved Intertrochanteric Varus Osteotomy vs Total Hip Arthroplasty for Osteonecrosis of the Femoral Head in Patients Under 50 Years Old50岁以下股骨转子间曲内翻截骨与全髋关节置换术治疗股骨头坏死
errJOURNAL OF ARTHROPLASTY
IF3.8
err2020-06-01
err11
PREAI
errOsawa, Yusuke; Seki, Taisuke; Okura, Toshiaki; Takegami, Yasuhiko; Ishiguro, Naoki; Hasegawa, Yukiharu
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Higher extracellular water-to-total body water ratio more strongly reflects the locomotive syndrome risk and frailty than sarcopenia
errARCHIVES OF GERONTOLOGY AND GERIATRICS
IF3.8
err2020-05-01
err23
PREAI
errTanaka, Satoshi; Ando, Kei; Kobayashi, Kazuyoshi; Nakashima, Hiroaki; Seki, Taisuke; Ishizuka, Shinya; Machino, Masaaki; Morozumi, Masayoshi; Kanbara, Shunsuke; Ito, Sadayuki; Inoue, Taro; Kanemura, Tokumi; Ishiguro, Naoki; Hasegawa, Yukiharu; Imagama, Shiro
err分享
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研究方向

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合作学者
合作期刊
D
Désirée van der Heijde
H 指数: 158 · 论文数: 1.3K
H
Harry K. Genant
H 指数: 146 · 论文数: 871
Y
Yuichi Sugiyama
H 指数: 112 · 论文数: 1.1K
T
Toshi A. Furukawa
H 指数: 104 · 论文数: 1.1K
G
Gen Sobue
H 指数: 102 · 论文数: 1.1K
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