未登录 Ex vivo drug testing identifies a potentially effective drug in 94% of cases for 403 patients in 42 tumor types Rosati, Rachele; Rajevski, Alex C.; Chatterjee, Payel; Appleyard, Lauren R.; Schmidt, Ana Cristina Cordero; Pereira, Shalini; Diaz, Robert L.; Bernard, Brady; Bernard, Brady; Grandori, Carla; Kemp, Christopher J. 分享 收藏
Case report: ex vivo tumor organoid drug testing identifies therapeutic options for stage IV ovarian carcinoma Al-Aloosi, Marwah; Prechtl, Amanda M.; Chatterjee, Payel; Bernard, Brady; Kemp, Christopher J.; Rosati, Rachele; Diaz, Robert L.; Appleyard, Lauren R.; Pereira, Shalini; Rajewski, Alex; Mcdonald, Amber; Gordon, Eva J.; Grandori, Carla 分享 收藏
Extraordinary clinical response to ibrutinib in low-grade ovarian cancer guided by organoid drug testing Gray, Heidi J.; Chatterjee, Payel; Rosati, Rachele; Appleyard, Lauren R.; Durenberger, Grace J.; Diaz, Robert L.; Swan, Hallie A.; Peretti, Danielle; Pollastro, Maddy; Ainge, Trevor; Kapeli, Katannya; Pereira, Shalini; Margossian, Astrid L.; Banda, Kalyan; Goff, Barbara A.; Swisher, Elizabeth M.; Bernard, Brady; Kemp, Christopher J.; Grandori, Carla 分享 收藏
Tumor organoid based drug sensitivity testing in ovarian cancer identifies exceptional responders to targeted therapies Prechtl, Amanda M.; Al-Aloosi, Marwah; Chatterjee, Payel; Rosati, Rachele; Velazquez, Samantha; Appleyard, Lauren; Durenberger, Grace; Cordero, Cristina; Diaz, Robert; Swan, Hallie; Bernard, Brady; Mukherjee, Siddhartha; Goff, Barbara; Swisher, Elizabeth; Gray, Heidi; Banda, Kalyan; Kemp, Christopher; Grandori, Carla 分享 收藏
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Pharmacologic Targeting of TFIIH Suppresses Synergizes with TRAIL Moser, Russell; Annis, James; Nikolova, Olga; Whatcott, Cliff; Gurley, Kay; Mendez, Eduardo; Moran-Jones, Kim; Dorrell, Craig; Sears, Rosalie C.; Kuo, Calvin; Han, Haiyong; Biankin, Andrew; Grandori, Carla; Von Hoff, Daniel D.; Kemp, Christopher J. 分享 收藏
Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma Moser, Russell; Gurley, Kay E.; Nikolova, Olga; Qin, Guangrong; Joshi, Rashmi; Mendez, Eduardo; Shmulevich, Ilya; Ashley, Amanda; Grandori, Carla; Kemp, Christopher J. 分享 收藏
Inhibition of FGF receptor blocks adaptive resistance to RET inhibition in CCDC6-RET-rearranged thyroid cancer Raman, Renuka; Villefranc, Jacques A. A.; Ullmann, Timothy M. M.; Thiesmeyer, Jessica; Anelli, Viviana; Yao, Jun; Hurley, James R. R.; Pauli, Chantal; Bareja, Rohan; Eng, Kenneth Wha; Dorsaint, Princesca; Wilkes, David C. C.; Beg, Shaham; Kudman, Sarah; Shaw, Reid; Churchill, Michael; Ahmed, Adnan; Keefer, Laurel; Misner, Ian; Nichol, Donna; Gumpeni, Naveen; Scognamiglio, Theresa; Rubin, Mark A. A.; Grandori, Carla; Solomon, James Patrick; Song, Wei; Mosquera, Juan Miguel; Dephoure, Noah; Sboner, Andrea; Elemento, Olivier; Houvras, Yariv 分享 收藏
Targeting BET Proteins BRD2 and BRD3 in Combination with PI3K-AKT Inhibition as a Therapeutic Strategy for Ovarian Clear Cell Carcinoma Shigeta, Shogo; Lui, Goldie Y. L.; Shaw, Reid; Moser, Russell; Gurley, Kay E.; Durenberger, Grace; Rosati, Rachele; Diaz, Robert L.; Ince, Tan A.; Swisher, Elizabeth M.; Grandori, Carla; Kemp, Christopher J. 分享 收藏
BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer BET,SRC和BCL2家族抑制剂与PARP抑制剂在卵巢癌中的协同药物组合 Lui, Goldie Y. L.; Shaw, Reid; Schaub, Franz X.; Stork, Isabella N.; Gurley, Kay E.; Bridgwater, Caroline; Diaz, Robert L.; Rosati, Rachele; Swan, Hallie A.; Ince, Tan A.; Harding, Thomas C.; Gadi, Vijayakrishna K.; Goff, Barbara A.; Kemp, Christopher J.; Swisher, Elizabeth M.; Grandori, Carla 分享 收藏
Organoid based functional test to predict personalized treatment in cholangiocarcinoma Margossian, Astrid; Schaub, Franz X.; Richardson, Annie; Churchill, Michael; Rosati, Rachele; Dullea, Alexandra; Whitney, G. Adam; Swan, Hallie; Diaz, Robert; Appleyard, Lauren; Gadi, Vijaykrishna; Zarrinpar, Ali; Javle, Milind; Kemp, Christopher; Pereira, Shalini; Grandori, Carla 分享 收藏
Repurposing dasatinib for diffuse large B cell lymphoma Scuoppo, Claudio; Wang, Jiguang; Persaud, Mirjana; Mittan, Sandeep K.; Basso, Katia; Pasqualucci, Laura; Rabadan, Raul; Inghirami, Giorgio; Grandori, Carla; Bosch, Francesc; Dalla-Favera, Riccardo 分享 收藏
Tyrosine kinase receptor TIE-1 mediates platinum resistance by promoting nucleotide excision repair in ovarian cancer Ishibashi, Masumi; Toyoshima, Masafumi; Zhang, Xuewei; Hasegawa-Minato, Junko; Shigeta, Shogo; Usui, Toshinori; Kemp, Christopher J.; Grandori, Carla; Kitatani, Kazuyuki; Yaegashi, Nobuo 分享 收藏
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Accelerating drug development with a CLIA approved functional test using patient derived organoids Schaub, Franz X.; Churchill, Michael J.; Swan, Hallie A.; Rosati, Rachele; Watt, Roland M.; Shaw, Reid C.; Murphy, Stephanie A.; Diaz, Robert L.; Pereira, Shalini C.; Grandori, Carla 分享 收藏
Personalization of cancer treatments with a CLIA-certified high-complexity and high-throughput drug sensitivity test Swan, Hallie A.; Churchill, Michael J.; Rosati, Rachele; Schaub, Franz X.; Shaw, Reid C.; Watt, Roland M.; Mendez, Eduardo; Kemp, Christopher J.; Gadi, Vijayakrishna K.; Murphy, Stephanie A.; Bernard, Brady; Diaz, Robert L.; Pereira, Shalini C.; Grandori, Carla 分享 收藏
Personalized medicine: A CLIA-certified high-throughput drug screening platform for ovarian cancer Swan, Hallie A.; Rosati, Rachele; Bridgwater, Caroline; Churchill, Michael J.; Watt, Roland M.; Shaw, Reid C.; Murphy, Stephanie A.; Diaz, Robert L.; Pereira, Shalini C.; Schaub, Franz X.; Grandori, Carla 分享 收藏
Patient derived tumor organoids identify actionable targets in heavily pretreated metastatic breast cancer patients Churchill, Michael J.; Schaub, Franz X.; Swan, Hallie A.; Rosati, Rachele; Yan, Fengting; Shaw, Reid C.; Gurley, Kay E.; Diaz, Robert L.; Pereira, Shalini C.; Grandori, Carla; Kemp, Christopher J.; Gadi, Vijayakrishna K. 分享 收藏
Patient derived organoids to model rare prostate cancer phenotypes Puca, Loredana; Bareja, Rohan; Prandi, Davide; Shaw, Reid; Benelli, Matteo; Karthaus, Wouter R.; Hess, Judy; Sigouros, Michael; Donoghue, Adam; Kossai, Myriam; Gao, Dong; Cyrta, Joanna; Sailer, Verena; Vosoughi, Aram; Pauli, Chantal; Churakova, Yelena; Cheung, Cynthia; Deonarine, Lesa Dayal; McNary, Terra J.; Rosati, Rachele; Tagawa, Scott T.; Nanus, David M.; Mosquera, Juan Miguel; Sawyers, Charles L.; Chen, Yu; Inghirami, Giorgio; Rao, Rema A.; Grandori, Carla; Elemento, Olivier; Sboner, Andrea; Demichelis, Francesca; Rubin, Mark A.; Beitrah, Himisha 分享 收藏