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C

Christoph Sotriffer

julius-maximilians-universitaet wuerzburg

41H指数
172论文数
5.4K被引数
收录论文 63
发表时间
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A Dual Approach To Combat Alzheimer’s Disease through Concomitant hBChE Inhibition and S1R Activation
errACS Chemical Neuroscience
IF3.9
err2026-01-27
err0
PREAI
errKora Reichau; Lucie Crouzier; Eleonora Poeta; Tina Gehrig; Eva Schaller; Liga Zvejniece; Johann Meunier; Christoph Sotriffer; Barbara Monti; Tangui Maurice; Michael Decker
err分享
err收藏
Targeting neuroinflammation by activation of the sigma-1 receptor (S1R) and inhibition of butyrylcholinesterase (hBChE) leads to highly potent anti-amnesic compounds in an Alzheimer's disease mouse model
errEuropean Journal of Medicinal Chemistry
IF5.9
err2025-12-13
err0
errOAAI
errKora Reichau; Lucie Crouzier; Tina Gehrig; Alix Flake; Eva Schaller; Johann Meunier; Christelle Bertrand-Gaday; Arnaud Chatonnet; Liga Zvejniece; Christoph Sotriffer; Tangui Maurice; Michael Decker
err分享
err收藏
Structural Optimization of Covalent Inhibitors for Deubiquitinase ChlaDUB1 of Chlamydia trachomatis as Antibiotic Agents共价抑制剂的结构优化，用于克氏嗜衣原体（Chlamydia trachomatis）的去泛素化酶ChlaDUB1，作为抗菌剂。
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2025-02-28
err0
PREAI
errZimmermann, Thomas; Feng, Jiachen; Fischer, Simon; de Campos, Luana Janaina; Pinheiro, Felipe Ramos; Sotriffer, Christoph; Conda-Sheridan, Martin
err分享
err收藏
High Affinity Inhibitors of the Macrophage Infectivity Potentiator Protein from Trypanosoma cruzi, Burkholderia pseudomallei, and Legionella pneumophila-A Comparison
errACS INFECTIOUS DISEASES
IF3.8
err2024-10-02
err1
PREAI
errLohr, Theresa; Herbst, Carina; Bzdyl, Nicole M.; Jenkins, Christopher; Scheuplein, Nicolas J.; Sugiarto, Wisely Oki; Whittaker, Jacob J.; Guskov, Albert; Norville, Isobel; Hellmich, Ute A.; Hausch, Felix; Sarkar-Tyson, Mitali; Sotriffer, Christoph; Holzgrabe, Ulrike
err分享
err收藏
Correlating Predicted Reactivities with Experimental Inhibition Data of Covalent ChlaDUB1 Inhibitors
errACS MEDICINAL CHEMISTRY LETTERS
IF4
err2024-09-10
err1
PREAI
errZimmermann, Thomas; Endres, Erik; Sotriffer, Christoph; Decker, Michael
err分享
err收藏
Structure-Based Design and Synthesis of Covalent Inhibitors for Deubiquitinase and Acetyltransferase ChlaDUB1 of Chlamydia trachomatis
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2024-06-19
err1
PREAI
errZimmermann, Thomas; Feng, Jiachen; de Campos, Luana Janaina; Knight, Lindsey A.; Schloetzer, Jan; Ramirez, Yesid A.; Schwickert, Kevin; Zehe, Markus; Adler, Thomas B.; Schirmeister, Tanja; Kisker, Caroline; Sotriffer, Christoph; Conda-Sheridan, Martin; Decker, Michael
err分享
err收藏
Structural basis for the bi-specificity of USP25 and USP28 inhibitorsUSP25和USP28抑制剂双特异性的结构基础
errEMBO REPORTS
IF6.2
err2024-05-30
err3
errOAAI
errPatzke, Jonathan Vincent; Sauer, Florian; Nair, Radhika Karal; Endres, Erik; Proschak, Ewgenij; Hernandez-Olmos, Victor; Sotriffer, Christoph; Kisker, Caroline
err分享
err收藏
Combined In-Solution Fragment Screening and Crystallographic Binding-Mode Analysis with a Two-Domain Hsp70 Construct
errACS CHEMICAL BIOLOGY
IF3.8
err2024-02-06
err1
PREAI
errZehe, Markus; Kehrein, Josef; Schollmayer, Curd; Plank, Christina; Kovacs, Helena; Merino Asumendi, Eduardo; Holzgrabe, Ulrike; Grimm, Clemens; Sotriffer, Christoph
err分享
err收藏
Molecular Dynamics Simulations for Rationalizing Polymer Bioconjugation Strategies: Challenges, Recent Developments, and Future Opportunities
errACS BIOMATERIALS SCIENCE & ENGINEERING
IF5.5
err2023-07-19
err4
PREAI
errKehrein, Josef; Sotriffer, Christoph
err分享
err收藏
MD-Based Assessment of Covalent Inhibitors in Noncovalent Association Complexes: Learning from Cathepsin K as a Test Case
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-05-11
err1
PREAI
errEndres, Erik; Chen, Natalia Yuan; Sotriffer, Christoph
err分享
err收藏
Unraveling an Alternative Mechanism in Polymer Self-Assemblies: An Order-Order Transition with Unusual Molecular Interactions between Hydrophilic and Hydrophobic Polymer Blocks
errACS NANO
IF16
err2023-03-27
err11
errOAAI
errHahn, Lukas; Zorn, Theresa; Kehrein, Josef; Kielholz, Tobias; Ziegler, Anna-Lena; Forster, Stefan; Sochor, Benedikt; Lisitsyna, Ekaterina S.; Durandin, Nikita A.; Laaksonen, Timo; Aseyev, Vladimir; Sotriffer, Christoph; Saalwaechter, Kay; Windbergs, Maike; Poeppler, Ann-Christin; Luxenhofer, Robert
err分享
err收藏
Bridging the Binding Sites: Dualsteric Ligands for the Cannabinoid 2 Receptor (CB2R)
errADVANCED THERAPEUTICS
IF2.6
err2023-02-25
err3
errOAAI
errTutov, Anna; Steinmueller, Sophie A. M.; Ramirez, Yesid A.; Jack, Christine E.; Rodriguez-Soacha, Diego A.; Sotriffer, Christoph; Hislop, James N.; Decker, Michael
err分享
err收藏
Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97
errCOMMUNICATIONS CHEMISTRY
IF6.2
err2022-12-07
err5
errOAAI
errBothe, Sebastian; Haenzelmann, Petra; Boehler, Stephan; Kehrein, Josef; Zehe, Markus; Wiedemann, Christoph; Hellmich, Ute A.; Brenk, Ruth; Schindelin, Hermann; Sotriffer, Christoph
err分享
err收藏
Glycolytic flux control by drugging phosphoglycolate phosphatase
errNATURE COMMUNICATIONS
IF15.7
err2022-11-11
err2
errOAAI
errJeanclos, Elisabeth; Schloetzer, Jan; Hadamek, Kerstin; Yuan-Chen, Natalia; Alwahsh, Mohammad; Hollmann, Robert; Fratz, Stefanie; Yesilyurt-Gerhards, Dilan; Frankenbach, Tina; Engelmann, Daria; Keller, Angelika; Kaestner, Alexandra; Schmitz, Werner; Neuenschwander, Martin; Hergenroeder, Roland; Sotriffer, Christoph; von Kries, Jens Peter; Schindelin, Hermann; Gohla, Antje
err分享
err收藏
New peptidomimetic rhodesain inhibitors with improved selectivity towards human cathepsins
errEUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
IF5.9
err2022-08-01
err10
PREAI
errJung, Sascha; Fuchs, Natalie; Grathwol, Christoph; Hellmich, Ute A.; Wagner, Annika; Diehl, Erika; Willmes, Thomas; Sotriffer, Christoph; Schirmeister, Tanja
err分享
err收藏
Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB1R) ?Cis-On? Agonist基于吲哚酰胺的光转换大麻素受体亚型1 (CB1R) 的开发？Cis-On?激动剂
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2022-07-26
err8
errOAAI
errRodriguez-Soacha, Diego A.; Steinmueller, Sophie A. M.; Isbilir, Ali; Fender, Julia; Deventer, Marie H.; Ramirez, Yesid A.; Tutov, Anna; Sotriffer, Christoph; Stove, Christophe P.; Lorenz, Kristina; Lohse, Martin J.; Hislop, James N.; Decker, Michael
err分享
err收藏
Photoswitchable Pseudoirreversible Butyrylcholinesterase Inhibitors Allow Optical Control of Inhibition in Vitro and Enable Restoration of Cognition in an Alzheimer's Disease Mouse Model upon Irradiation
errJOURNAL OF THE AMERICAN CHEMICAL SOCIETY
IF15.6
err2022-02-09
err26
PREAI
errScheiner, Matthias; Sink, Alexandra; Hoffmann, Matthias; Vrigneau, Cassandre; Endres, Erik; Carles, Allison; Sotriffer, Christoph; Maurice, Tangui; Decker, Michael
err分享
err收藏
Molecular Insights into Site-Specific Interferon-α2a Bioconjugates Originated from PEG, LPG, and PEtOx
errBIOMACROMOLECULES
IF5.4
err2021-10-13
err22
PREAI
errHauptstein, Niklas; Pouyan, Paria; Kehrein, Josef; Dirauf, Michael; Driessen, Marc D.; Raschig, Martina; Licha, Kai; Gottschaldt, Michael; Schubert, Ulrich S.; Haag, Rainer; Meinel, Lorenz; Sotriffer, Christoph; Luehmann, Tessa
err分享
err收藏
Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2021-05-13
err42
errOAAI
errDoelle, Anja; Adhikari, Bikash; Kraemer, Andreas; Weckesser, Janik; Berner, Nicola; Berger, Lena-Marie; Diebold, Mathias; Szewczyk, Magdalena M.; Barsyte-Lovejoy, Dalia; Arrowsmith, Cheryl H.; Gebel, Jakob; Loehr, Frank; Doetsch, Volker; Eilers, Martin; Heinzlmeir, Stephanie; Kuster, Bernhard; Sotriffer, Christoph; Wolf, Elmar; Knapp, Stefan
err分享
err收藏
Photo-Rimonabant: Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar Cis-On CB1R Antagonist
errACS CHEMICAL NEUROSCIENCE
IF3.9
err2021-04-15
err16
errOAAI
errRodriguez-Soacha, Diego A.; Fender, Julia; Ramirez, Yesid A.; Antonio Collado, Juan; Munoz, Eduardo; Maitra, Rangan; Sotriffer, Christoph; Lorenz, Kristina; Decker, Michael
err分享
err收藏

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