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S

Sagrario Ortega

cnio
H指数:53
被引数:1.3万

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miR-203 facilitates timely cell fate transitions via epigenetic modulation during early embryogenesis

miR-203通过表观遗传调控促进早期胚胎发育过程中的适时细胞命运转变。

Science Advances
IF12.5
2026-03-110
OA
José González-Martínez; Agustín Sánchez-Belmonte; Estefanía Ayala; Beatriz Escobar; Jesús Gómez; Alejandro García-Díaz; Enrique Nogueira; Jaime Muñoz; Anna Melati; Andreas Brandauer; Daniel Giménez-Llorente; Isabel Peset; Ana Losada; Sagrario Ortega; Marcos Malumbres
A Common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

一种与胰腺癌风险相关的常见CTRB错折叠变异体可导致小鼠内质网应激和炎症。

GUT
IF25.8
2025-04-190
PRE
Bodas, Cristina; Felipe, Irene; Chanez, Brice; Lafarga, Miguel; Lopez de Maturana, Evangelina; Martinez de Villarreal, Jaime; del Pozo, Natalia; Malumbres, Marina; Vargiu, Pierfrancesco; Cayuela, Ana; Peset, Isabel; Connelly, Katelyn; Hoskins, Jason; Mendez, Raul; Amundadottir, Laufey; Malats, Nuria; Ortega, Sagrario; Real, Francisco X.
T Cell-Specific Inactivation of the PI3K p110α Catalytic Subunit: Effect in T Cell Differentiation and Antigen-Specific Responses

T细胞特异性失活PI3K p110α催化亚基：对T细胞分化和抗原特异性反应的影响

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
IF4.9
2025-01-120
OA
Briones, Alejandro C.; del Estal, Laura; Villa-Gomez, Cristina; Bermejo, Veronica; Cervera, Isabel; Gutierrez-Huerta, Pedro; Montes-Casado, Maria; Ortega, Sagrario; Barbacid, Mariano; Rojo, Jose Maria; Portoles, Pilar
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation (vol 68, pg 336, 2017)
MOLECULAR CELL
IF16.6
2024-06-010
OAAI
Lopez-Mejia, Isabel C.; Lagarrigue, Sylviane; Giralt, Albert; Martinez-Carreres, Laia; Martin, Javier; Ortega, Sagrario; Zanou, Nadege; Denechaud, Pierre-Damien; Castillo-Armengol, Judit; Chavey, Carine; Orpinell, Meritxell; Delacuisine, Brigitte; Nasrallah, Anita; Collodet, Caterina; Zhang, Lianjun; Viollet, Benoit; Hardie, D. Grahame; Fajas, Lluis
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype

铁积累驱动纤维化，衰老和衰老相关的分泌表型

NATURE METABOLISM
IF20.8
2023-12-1438
OAAI
Maus, Mate; Lopez-Polo, Vanessa; Mateo, Lidia; Lafarga, Miguel; Aguilera, Monica; De Lama, Eugenia; Meyer, Kathleen; Sola, Anna; Lopez-Martinez, Cecilia; Lopez-Alonso, Ines; Guasch-Piqueras, Marc; Hernandez-Gonzalez, Fernanda; Chaib, Selim; Rovira, Miguel; Sanchez, Mayka; Faner, Rosa; Agusti, Alvar; Dieguez-Hurtado, Rodrigo; Ortega, Sagrario; Manonelles, Anna; Engelhardt, Stefan; Monteiro, Freddy; Attolini, Camille Stephan-Otto; Prats, Neus; Albaiceta, Guillermo; Cruzado, Josep M.; Serrano, Manuel
Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2023-04-0316
OAAI
Salmon, Marina; Alvarez-Diaz, Ruth; Fustero-Torre, Coral; Brehey, Oksana; Lechuga, Carmen G.; Sanclemente, Manuel; Fernandez-Garcia, Fernando; Lopez-Garcia, Alejandra; Martin-Guijarro, Maria Carmen; Rodriguez-Perales, Sandra; Bousquet-Mur, Emily; Morales-Cacho, Lucia; Mulero, Francisca; Al-Shahrour, Fatima; Martinez, Lola; Dominguez, Orlando; Caleiras, Eduardo; Ortega, Sagrario; Guerra, Carmen; Musteanu, Monica; Drosten, Matthias; Barbacid, Mariano
Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3′ untranslated region
GENOME BIOLOGY
IF9.4
2022-10-311
OAAI
Fernandez, Lara P.; Deleyto-Seldas, Nerea; Colmenarejo, Gonzalo; Sanz, Alba; Wagner, Sonia; Belen Plata-Gomez, Ana; Gomez-Patino, Monica; Molina, Susana; Espinosa-Salinas, Isabel; Aguilar-Aguilar, Elena; Ortega, Sagrario; Grana-Castro, Osvaldo; Loria-Kohen, Viviana; Fernandez-Marcos, Pablo J.; Efeyan, Alejo; Ramirez de Molina, Ana
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism

黑色素瘤来源的小胞外囊泡通过NGFR依赖机制诱导淋巴管生成和转移

NATURE CANCER
IF28.5
2021-11-2592
OAAI
Garcia-Silva, Susana; Benito-Martin, Alberto; Nogues, Laura; Hernandez-Barranco, Alberto; Mazariegos, Marina S.; Santos, Vanesa; Hergueta-Redondo, Marta; Ximenez-Embun, Pilar; Kataru, Raghu P.; Lopez, Ana Amor; Merino, Cristina; Sanchez-Redondo, Sara; Grana-Castro, Osvaldo; Matei, Irina; Nicolas-Avila, Jose Angel; Torres-Ruiz, Raul; Rodriguez-Perales, Sandra; Martinez, Lola; Perez-Martinez, Manuel; Mata, Gadea; Kalinowska, Iwona; Saltari, Annalisa; Martinez-Gomez, Julia M.; Hogan, Sabrina A.; Saragovi, H. Uri; Ortega, Sagrario; Garcia-Martin, Carmen; Boskovic, Jasminka; Levesque, Mitchell P.; Rutkowski, Piotr; Hidalgo, Andres; Munoz, Javier; Megias, Diego; Mehrara, Babak J.; Lyden, David; Peinado, Hector
Deficient adaptation to centrosome duplication defects in neural progenitors causes microcephaly and subcortical heterotopias

对神经祖细胞中心体复制缺陷的适应不足导致小头畸形和皮质下异位

JCI INSIGHT
IF6.1
2021-08-2311
OA
Gonzalez-Martinez, Jose; Cwetsch, Andrzej W.; Martinez-Alonso, Diego; Lopez-Sainz, Luis R.; Almagro, Jorge; Melati, Anna; Gomez, Jesus; Perez-Martinez, Manuel; Megias, Diego; Boskovic, Jasminka; Gilabert-Juan, Javier; Grana-Castro, Osvaldo; Pierani, Alessandra; Behrens, Axel; Ortega, Sagrario; Malumbres, Marcos
Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2021-03-01189
OA
Miguel, Veronica; Tituana, Jessica; Ignacio Herrero, J.; Herrero, Laura; Serra, Dolors; Cuevas, Paula; Barbas, Coral; Rodriguez Puyol, Diego; Marquez-Exposito, Laura; Ruiz-Ortega, Marta; Castillo, Carolina; Sheng, Xin; Susztak, Katalin; Ruiz-Canela, Miguel; Salas-Salvado, Jordi; Martinez Gonzalez, Miguel A.; Ortega, Sagrario; Ramos, Ricardo; Lamas, Santiago
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases

增强子的全局超活化通过抑制CDK8/19介质激酶来稳定人类和小鼠的幼稚多能性

NATURE CELL BIOLOGY
IF19.1
2020-09-2838
OA
Lynch, Cian J.; Bernad, Raquel; Martinez-Val, Ana; Shahbazi, Marta N.; Nobrega-Pereira, Sandrina; Calvo, Isabel; Blanco-Aparicio, Carmen; Tarantino, Carolina; Garreta, Elena; Richart-Gines, Laia; Alcazar, Noelia; Grana-Castro, Osvaldo; Gomez-Lopez, Gonzalo; Aksoy, Irene; Munoz-Martin, Maribel; Martinez, Sonia; Ortega, Sagrario; Prieto, Susana; Simboeck, Elisabeth; Camasses, Alain; Stephan-Otto Attolini, Camille; Fernandez, Agustin F.; Sierra, Marta I.; Fraga, Mario F.; Pastor, Joaquin; Fisher, Daniel; Montserrat, Nuria; Savatier, Pierre; Munoz, Javier; Zernicka-Goetz, Magdalena; Serrano, Manuel

研究方向

暂未获取到该数据
M
Marcos Malumbres
H 指数:74论文数:365被引数:3.0万
M
Mariano Barbacid
H 指数:120论文数:425被引数:6.6万
M
Manuel Serrano
H 指数:98论文数:541被引数:7.6万
I
Inés Martínez‐Corral
H 指数:24论文数:42被引数:2,974
M
Marı́a A. Blasco
H 指数:114论文数:505被引数:6.7万
Ó
Óscar Fernández-Capetillo
H 指数:60论文数:171被引数:2.0万
J
Javier Muñoz
H 指数:44论文数:277被引数:8,222
D
Diego Megı́as
H 指数:44论文数:162被引数:7,764
O
Osvaldo Graña‐Castro
H 指数:43论文数:277被引数:6,833
T
Taija Mäkinen
H 指数:65论文数:161被引数:1.8万