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Comparative biological activity of palbociclib and ribociclib in hormone receptor-positive breast cancer Lorman-Carbo, Natalia; Martinez-Saez, Olga; Fernandez-Martinez, Aranzazu; Galvan, Patricia; Chic, Nuria; Garcia-Fructuoso, Isabel; Rodriguez, Adela; Gomez-Bravo, Raquel; Schettini, Francesco; Blasco, Paula; Castillo, Oleguer; Gonzalez-Farre, Blanca; Adamo, Barbara; Vidal, Maria; Munoz, Montserrat; Perou, Charles M.; Malumbres, Marcos; Gavila, Joaquin; Pascual, Tomas; Prat, Aleix; Braso-Maristany, Fara 分享 收藏
PP2A-B55 phosphatase counteracts Ki-67-dependent chromosome individualization during mitosis Sanz-Flores, Maria; Ruiz-Torres, Miguel; Aguirre-Portoles, Cristina; El Bakkali, Aicha; Salvador-Barbero, Beatriz; Villarroya-Beltri, Carolina; Ortega, Sagrario; Megias, Diego; Gerlich, Daniel W.; Alvarez-Fernandez, Monica; Malumbres, Marcos 分享 收藏
PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models PLK1抑制抑制炎症性疾病模型中NLRP3炎性体引起的反应 Baldrighi, Marta; Doreth, Christian; Li, Yang; Zhao, Xiaohui; Warner, Emily; Chenoweth, Hannah; Kishore, Kamal; Umrania, Yagnesh; Minde, David-Paul; Thome, Sarah; Yu, Xian; Lu, Yuning; Knapton, Alice; Harrison, James; Clarke, Murray; Latz, Eicke; de Carcer, Guillermo; Malumbres, Marcos; Ryffel, Bernhard; Bryant, Clare; Liu, Jinping; Lilley, Kathryn S.; Mallat, Ziad; Li, Xuan 分享 收藏
First results of the SOLTI-1903 HOPE's patient-centric molecular screening program in advanced breast cancer SOLTI-1903希望以患者为中心的晚期乳腺癌分子筛查计划的第一个结果 Pascual, T.; Segui Solis, E.; Olivera-Salguero, R.; Cejalvo, J. M.; Oliveira, M.; Tolosa Ortega, P.; Vidal Losada, M. J.; Malumbres, M.; Gavila-Gregori, J.; Saura Manich, C.; Pernas Simon, S.; Margeli Vila, M.; Ciruelos, E. M.; Galve-Calvo, E.; Galvan, P.; Sanfeliu Torres, E.; Olmos, R.; Forns, M.; Fernandez Tejerina, A. Casas; Prat, A. 分享 收藏
miR-203 drives breast cancer cell differentiation miR-203驱动乳腺癌细胞分化 Martinez-Illescas, Nuria G.; Leal, Silvia; Gonzalez, Patricia; Grana-Castro, Osvaldo; Munoz-Oliveira, Juan Jose; Cortes-Pena, Alfonso; Gomez-Gil, Maria; Vega, Zaira; Neva, Veronica; Romero, Andrea; Quintela-Fandino, Miguel; Ciruelos, Eva; Sanz, Consuelo; Aragon, Sofia; Sotolongo, Leisy; Jimenez, Sara; Caleiras, Eduardo; Mulero, Francisca; Sanchez, Cristina; Malumbres, Marcos; Salazar-Roa, Maria 分享 收藏
CoQ10 reduces glioblastoma growth and infiltration through proteome remodeling and inhibition of angiogenesis and inflammation (vol 46, pg 65, 2022) Frontinan-Rubio, Javier; Llanos-Gonzalez, Emilio; Garcia-Carpintero, Sonia; Peinado, Juan Ramon; Ballesteros-Yanez, Inmaculada; Rayo, Margarita Villar; de la Fuente, Jose; Perez-Garcia, Victor M.; Perez-Romasanta, Luis A.; Malumbres, Marcos; Alcain, Francisco J.; Duran-Prado, Mario 分享 收藏
Decoding protein methylation function with thermal stability analysis 用热稳定性分析解码蛋白质甲基化函数 Sayago, Cristina; Sanchez-Wandelmer, Jana; Garcia, Fernando; Hurtado, Begona; Lafarga, Vanesa; Prieto, Patricia; Zarzuela, Eduardo; Ximenez-Embun, Pilar; Ortega, Sagrario; Megias, Diego; Fernandez-Capetillo, Oscar; Malumbres, Marcos; Munoz, Javier 分享 收藏
HOPE (SOLTI-1903) breast cancer study: real-world, patient-centric, clinical practice study to assess the impact of genomic data on next treatment decision-choice in patients with locally advanced or metastatic breast cancer HOPE (SOLTI-1903) 乳腺癌研究: 以患者为中心的真实世界临床实践研究，评估基因组数据对局部晚期或转移性乳腺癌患者下一步治疗决策选择的影响 Olivera-Salguero, Ruben; Segui, Elia; Cejalvo, Juan Miguel; Oliveira, Mafalda; Tolosa, Pablo; Vidal, Maria; Malumbres, Marcos; Gavila, Joaquin; Saura, Cristina; Pernas, Sonia; Lopez, Rafael; Margeli, Mireia; Balmana, Judith; Munoz, Montserrat; Blancas, Isabel; Boni, Valentina; Ciruelos, Eva; Galve, Elena; Perello, Antonia; Sanchez-Bayona, Rodrigo; de la Cruz, Susana; de la Hoya, Miguel; Galvan, Patricia; Sanfeliu, Esther; Gonzalez-Farre, Blanca; Sirenko, Valeria; Blanch-Torras, Aura; Canes, Jordi; Masanas, Helena; Olmos, Rosa; Forns, Margarita; Prat, Aleix; Casas, Ana; Pascual, Tomas 分享 收藏
Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development Esteban, LM; Vicario-Abejón, C; Fernández-Salguero, P; Fernández-Medarde, A; Swaminathan, N; Yienger, K; Lopez, E; Malumbres, M; McKay, R; Ward, JM; Pellicer, A; Santos, E 分享 收藏
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Aurora B Overexpression Causes Aneuploidy and p21Cip1 Repression during Tumor Development Aurora B过表达导致肿瘤发展过程中的非整倍性和p21Cip1抑制 Gonzalez-Loyola, Alejandra; Fernandez-Miranda, Gonzalo; Trakala, Marianna; Partida, David; Samejima, Kumiko; Ogawa, Hiromi; Canamero, Marta; de Martino, Alba; Martinez-Ramirez, Angel; de Carcer, Guillermo; Perez de Castro, Ignacio; Earnshaw, William C.; Malumbres, Marcos 分享 收藏
Plk5, a Polo Box Domain-Only Protein with Specific Roles in Neuron Differentiation and Glioblastoma Suppression Plk5，一种仅Polo盒结构域的蛋白，在神经元分化和胶质母细胞瘤抑制中具有特定作用 de Carcer, Guillermo; Escobar, Beatriz; Higuero, Alonso M.; Garcia, Laura; Anson, Alejandra; Perez, Gema; Mollejo, Manuela; Manning, Gerard; Melendez, Barbara; Abad-Rodriguez, Jose; Malumbres, Marcos 分享 收藏
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p27Kip1 V109G as a biomarker for CDK4/6 inhibitors indication in hormone receptor-positive breast cancer p27Kip1 V109G作为激素受体阳性乳腺癌中CDK4/6抑制剂指示的生物标志物 Mouron, Silvana; Bueno, Maria J.; Munoz, Manuel; Torres, Raul; Rodriguez, Sandra; Apala, Juan, V; Silva, Jorge; Sanchez-Bayona, Rodrigo; Manso, Luis; Guerra, Juan; Rodriguez-Lajusticia, Laura; Malon, Diego; Malumbres, Marcos; Quintela-Fandino, Miguel 分享 收藏
Harnessing transcriptionally driven chromosomal instability adaptation to target therapy-refractory lethal prostate cancer 利用转录驱动的染色体不稳定性适应靶向治疗难治性致死性前列腺癌 Dhital, Brittiny; Santasusagna, Sandra; Kirthika, Perumalraja; Xu, Michael; Li, Peiyao; Carceles-Cordon, Marc; Soni, Rajesh K.; Li, Zhuoning; Hendrickson, Ronald C.; Schiewer, Matthew J.; Kelly, William K.; Sternberg, Cora N.; Luo, Jun; Lujambio, Amaia; Cordon-Cardo, Carlos; Alvarez-Fernandez, Monica; Malumbres, Marcos; Huang, Haojie; Ertel, Adam; Domingo-Domenech, Josep; Rodriguez-Bravo, Veronica 分享 收藏
Phosphoproteomic analysis of neoadjuvant breast cancer suggests that increased sensitivity to paclitaxel is driven by CDK4 and filamin A Mouron, S.; Bueno, M. J.; Lluch, A.; Manso, L.; Calvo, I; Cortes, J.; Garcia-Saenz, J. A.; Gil-Gil, M.; Martinez-Janez, N.; Apala, J., V; Caleiras, E.; Ximenez-Embun, Pilar; Munoz, J.; Gonzalez-Cortijo, L.; Murillo, R.; Sanchez-Bayona, R.; Cejalvo, J. M.; Gomez-Lopez, G.; Fustero-Torre, C.; Sabroso-Lasa, S.; Malats, N.; Martinez, M.; Moreno, A.; Megias, D.; Malumbres, M.; Colomer, R.; Quintela-Fandino, M. 分享 收藏
The MASTL/PP2A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner MASTL/PP2A细胞周期激酶-磷酸酶模块以mTORC1-dependent方式抑制PI3K-Akt活性 Sanz-Castillo, Belen; Hurtado, Begona; Vara-Ciruelos, Diana; El Bakkali, Aicha; Hermida, Dario; Salvador-Barbero, Beatriz; Martinez-Alonso, Diego; Gonzalez-Martinez, Jose; Santiveri, Clara; Campos-Olivas, Ramon; Ximenez-Embun, Pilar; Munoz, Javier; Alvarez-Fernandez, Monica; Malumbres, Marcos 分享 收藏
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