Holger Stark - Publications, H-index & Citations

Holger Stark

Fassberg

78H指数

275论文数

2.1W被引数

收录论文 75

发表时间

2′-O-methylation-dependent installation of N2-methylguanosine in the U6 internal stem loop facilitates efficient spliceosome assembly 2′-O-甲基化依赖性的N2-甲基鸟苷在U6内茎环中的安装促进了高效的剪接体组装

Nature Communications

IF15.7

2026-04-24

OAAI

Nicole Kleiber; Jonny Petrosyan; Maria Greve; Chairini C. Thomé; Olexandr Dybkov; Laurianne L. E. Tay; Luisa M. Welp; Philipp Hackert; David Touboul; Holger Stark; Markus T. Bohnsack; Henning Urlaub; Lydia Herzel; Marc Graille; Claudia Höbartner; Katherine E. Bohnsack

Incorporating immune cell surrogates into a full-thickness tissue equivalent of human skin to characterize dendritic cell activation

SCIENTIFIC REPORTS

IF3.9

2024-12-04

OAAI

Hoelken, Johanna Maria; Wurz, Anna-Lena; Friedrich, Katja; Boettcher, Patricia; Asskali, Dounia; Stark, Holger; Breitkreutz, Joerg; Buhl, Timo; Vierkotten, Lars; Mewes, Karsten Ruediger; Teusch, Nicole

Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins 二聚剪接体的cryo-em分析为B复合蛋白的功能提供了新的见解

EMBO JOURNAL

IF8.3

2024-02-21

OAAI

Zhang, Zhenwei; Kumar, Vinay; Dybkov, Olexandr; Will, Cindy L.; Urlaub, Henning; Stark, Holger; Luehrmann, Reinhard

Protein composition and electron microscopy structure of affinity-purified human spliceosomal B complexes isolated under physiological conditions

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

283

OAAI

Deckert, Jochen; Hartmuth, Maus; Boehringer, Daniel; Behzadnia, Nastaran; Will, Cindy L.; Kastner, Berthold; Stark, Holger; Urlaub, Henning; Luehrmann, Reinhard

Conformational rearrangements upon start codon recognition in human 48S translation initiation complex

NUCLEIC ACIDS RESEARCH

IF13.1

2022-04-30

OAAI

Yi, Sung-Hui; Petrychenko, Valentyn; Schliep, Jan Erik; Goyal, Akanksha; Linden, Andreas; Chari, Ashwin; Urlaub, Henning; Stark, Holger; Rodnina, Marina, V; Adio, Sarah; Fischer, Niels

Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome

MOLECULAR CELL

IF16.6

2020-10-01

OAAI

Bertram, Karl; El Ayoubi, Leyla; Dybkov, Olexandr; Agafonov, Dmitry E.; Will, Cindy L.; Hartmuth, Klaus; Urlaub, Henning; Kastner, Berthold; Stark, Holger; Luehrmann, Reinhard

Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2019-07-26

OAAI

Watson, Edmond R.; Grace, Christy R. R.; Zhang, Wei; Miller, Darcie J.; Davidson, Iain F.; Prabu, J. Rajan; Yu, Shanshan; Bolhuis, Derek L.; Kulko, Elizaveta T.; Vollrath, Ronnald; Haselbach, David; Stark, Holger; Peters, Jan-Michael; Brown, Nicholas G.; Sidhu, Sachdev S.; Schulman, Brenda A.

Structural Insights into Nuclear p e-mRNA Splicing in Higher Eukaryotes

cold spring harbor perspectives in medicine

IF8.4

2019-02-14

153

OAAI

Kastner, Berthold; Will, Cindy L.; Stark, Holger; Luehrmann, Reinhard

Posh the APC/C E3 Ubiquitin Licase to Orchestrate Cell Division

TRENDS IN CELL BIOLOGY

IF18.1

2019-02-01

OAAI

Watson, Edmond R.; Brown, Nicholas G.; Peters, Jan-Michael; Stark, Holger; Schulman, Brenda A.

Cryo-EM in drug discovery: achievements, limitations and prospects

NATURE REVIEWS DRUG DISCOVERY

IF101.8

2018-06-08

322

PREAI

Renaud, Jean-Paul; Chari, Ashwin; Ciferri, Claudio; Liu, Wen-ti; Remigy, Herve-William; Stark, Holger; Wiesmann, Christian

Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs

NATURE COMMUNICATIONS

IF15.7

2017-05-25

OAAI

Haselbach, David; Schrader, Jil; Lambrecht, Felix; Henneberg, Fabian; Chari, Ashwin; Stark, Holger

Ribosome dynamics during decoding

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2017-03-19

OAAI

Rodnina, Marina V.; Fischer, Niels; Maracci, Cristina; Stark, Holger

The Ribosome Cooperates with the Assembly Chaperone pICln to Initiate Formation of snRNPs

CELL REPORTS

IF6.9

2016-09-01

OAAI

Paknia, Elham; Chari, Ashwin; Stark, Holger; Fischer, Utz

Topology and structure of an engineered human cohesin complex bound to Pds5B

NATURE COMMUNICATIONS

IF15.7

2016-08-23

OAAI

Hons, Michael T.; in't Veld, Pim J. Huis; Kaesler, Jan; Rombaut, Pascaline; Schleiffer, Alexander; Herzog, Franz; Stark, Holger; Peters, Jan-Michael

Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation

MOLECULAR CELL

IF16.6

2016-08-01

120

OAAI

Yamaguchi, Masaya; VanderLinden, Ryan; Weissmann, Florian; Qiao, Renping; Dube, Prakash; Brown, Nicholas G.; Haselbach, David; Zhang, Wei; Sidhu, Sachdev S.; Peters, Jan-Michael; Stark, Holger; Schulman, Brenda A.

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes biGBac可以快速组装基因，以表达大型多亚基蛋白复合物

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-04-25

219

OAAI

Weissmann, Florian; Petzold, Georg; VanderLinden, Ryan; in'T Veld, Pim J. Huis; Brown, Nicholas G.; Lampert, Fabienne; Westermann, Stefan; Stark, Holger; Schulman, Brenda A.; Peters, Jan-Michael

Mechanism of APC/CCDC20 activation by mitotic phosphorylation

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-04-25

129

OAAI

Qiao, Renping; Weissmann, Florian; Yamaguchi, Masaya; Brown, Nicholas G.; VanderLinden, Ryan; Imre, Richard; Jarvis, Marc A.; Brunner, Michael R.; Davidson, Iain F.; Litos, Gabriele; Haselbach, David; Mechtler, Karl; Stark, Holger; Schulman, Brenda A.; Peters, Jan-Michael

Nanobodies: site-specific labeling for super-resolution imaging, rapid epitope-mapping and native protein complex isolation

ELIFE

IF0

2015-12-03

186

OAAI

Pleiner, Tino; Bates, Mark; Trakhanov, Sergei; Lee, Chung-Tien; Schliep, Jan Erik; Chug, Hema; Boehning, Marc; Stark, Holger; Urlaub, Henning; Goerlich, Dirk

ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space

NATURE METHODS

IF32.1

2015-08-03

OAAI

Chari, Ashwin; Haselbach, David; Kirves, Jan-Martin; Ohmer, Juergen; Paknia, Elham; Fischer, Niels; Ganichkin, Oleg; Moeller, Vanessa; Frye, Jeremiah J.; Petzold, Georg; Jarvis, Marc; Tietzel, Michael; Grimm, Clemens; Peters, Jan-Michael; Schulman, Brenda A.; Tittmann, Kai; Markl, Juergen; Fischer, Utz; Stark, Holger

Molecular Basis of Transcription-Coupled Pre-mRNA Capping

MOLECULAR CELL

IF16.6

2015-06-01

104

OAAI

Martinez-Rucobo, Fuensanta W.; Kohler, Rebecca; van de Waterbeemd, Michiel; Heck, Albert J. R.; Hemann, Matthias; Herzog, Franz; Stark, Holger; Cramer, Patrick

研究方向