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M

Muireann Coen

AstraZeneca
H指数:40
被引数:5,797

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Meet-in-the-middle meets multi-omics identifying molecular signatures of environmental drivers of childhood overweight

Meet-in-the-middle方法结合多组学技术，识别环境因素驱动儿童超重的分子标志物

Environment International
IF9.7
2025-06-230
OA
Congrong Wang; Brigitte Reimann; Tim S Nawrot; Dries S Martens; John Wright; Rosemary McEachan; Johanna Lepeule; Wenlun Yuan; Leda Chatzi; Marina Vafeiadi; Regina Grazuleviciene; Sandra Andrusaityte; Oliver Robinson; Jordi Sunyer; Hector Keun; Chung-Ho E. Lau; Alexandros P. Siskos; Muireann Coen; Eva Borràs; Eduard Sabidó; Rossella Alfano
Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition
ARCHIVES OF TOXICOLOGY
IF6.9
2024-05-170
OAAI
Fogal, Valentina; Michopoulos, Filippos; Jarnuczak, Andrew F.; Hamza, Ghaith M.; Harlfinger, Stephanie; Davey, Paul; Hulme, Heather; Atkinson, Stephen J.; Gabrowski, Piotr; Cheung, Tony; Grondine, Michael; Hoover, Clare; Rose, Jonathan; Bray, Chandler; Foster, Alison J.; Askin, Sean; Majumder, Muntasir Mamun; Fitzpatrick, Paul; Miele, Eric; Macdonald, Ruth; Keun, Hector C.; Coen, Muireann
Development of a Series of Pyrrolopyridone MAT2A Inhibitors
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2024-03-113
PRE
Atkinson, Stephen J.; Bagal, Sharan K.; Argyrou, Argyrides; Askin, Sean; Cheung, Tony; Chiarparin, Elisabetta; Coen, Muireann; Collie, Iain T.; Dale, Ian L.; De Fusco, Claudia; Dillman, Keith; Evans, Laura; Feron, Lyman J.; Foster, Alison J.; Grondine, Michael; Kantae, Vasudev; Lamont, Gillian M.; Lamont, Scott; Lynch, James T.; Lill, Sten Nilsson; Robb, Graeme R.; Saeh, Jamal; Schimpl, Marianne; Scott, James S.; Smith, James; Srinivasan, Bharath; Tentarelli, Sharon; Vazquez-Chantada, Mercedes; Wagner, David; Walsh, Jarrod J.; Watson, David; Williamson, Beth
In-utero and childhood chemical exposome in six European mother-child cohorts ( vol 121 , pg 751-763 , 2018 )

六个欧洲母子队列中的子宫内和儿童化学暴露组 (121卷，751至763页，2018)

ENVIRONMENT INTERNATIONAL
IF9.7
2024-03-010
OAAI
Haug, Line Smastuen; Sakhi, Amrit Kaur; Cequier, Enrique; Casas, Maribel; Maitre, Lea; Basagana, Xavier; Andrusaityte, Sandra; Chalkiadaki, Georgia; Chatzi, Leda; Coen, Muireann; de Bont, Jeroen; Dedele, Audrius; Ferrand, Joane; Grazuleviciene, Regina; Gonzalez, Juan Ramon; Gutzkow, Kristine Bjerve; Keun, Hector; McEachan, Rosie; Meltzer, Helle Margrete; Petraviciene, Inga; Robinson, Oliver; Saulnier, Pierre -Jean; Slama, Remy; Sunyer, Jordi; Urquiza, Jose; Vafeiadi, Marina; Wright, John; Vrijheid, Martine; Thomsen, Cathrine
Lysophosphatidylcholines modulate immunoregulatory checkpoints in peripheral monocytes and are associated with mortality in people with acute liver failure
JOURNAL OF HEPATOLOGY
IF33
2023-03-0124
OAAI
Trovato, Francesca M.; Zia, Rabiya; Artru, Florent; Mujib, Salma; Jerome, Ellen; Cavazza, Anna; Coen, Muireann; Wilson, Ian; Holmes, Elaine; Morgan, Phillip; Singanayagam, Arjuna; Bernsmeier, Christine; Napoli, Salvatore; Bernal, William; Wendon, Julia; Miquel, Rosa; Menon, Krishna; Patel, Vishal C.; Smith, John; Atkinson, Stephen R.; Triantafyllou, Evangelos; McPhail, Mark J. W.
Multi-omics signatures of the human early life exposome

人类早期生命暴露组的多组学特征

NATURE COMMUNICATIONS
IF15.7
2022-11-2159
OAAI
Maitre, Lea; Bustamante, Mariona; Hernandez-Ferrer, Carles; Thiel, Denise; Lau, Chung-Ho E.; Siskos, Alexandros; Vives-Usano, Marta; Ruiz-Arenas, Carlos; Pelegri-Siso, Dolors; Robinson, Oliver; Mason, Dan; Wright, John; Cadiou, Solene; Slama, Remy; Heude, Barbara; Casas, Maribel; Sunyer, Jordi; Papadopoulou, Eleni Z.; Gutzkow, Kristine B.; Andrusaityte, Sandra; Grazuleviciene, Regina; Vafeiadi, Marina; Chatzi, Leda; Sakhi, Amrit K.; Thomsen, Cathrine; Tamayo, Ibon; Nieuwenhuijsen, Mark; Urquiza, Jose; Borras, Eva; Sabido, Eduard; Quintela, Ines; Carracedo, Angel; Estivill, Xavier; Coen, Muireann; Gonzalez, Juan R.; Keun, Hector C.; Vrijheid, Martine
Rifaximin-α reduces gut-derived inflammation and mucin degradation in cirrhosis and encephalopathy: RIFSYS randomised controlled trial

利福昔明-α 减少肝硬化和脑病的肠源性炎症和粘蛋白降解: RIFSYS随机对照试验

JOURNAL OF HEPATOLOGY
IF33
2022-02-01107
OA
Patel, Vishal C.; Lee, Sunjae; McPhail, Mark J. W.; Da Silva, Kevin; Guilly, Susie; Zamalloa, Ane; Witherden, Elizabeth; Stoy, Sidsel; Vijay, Godhev Kumar Manakkat; Pons, Nicolas; Galleron, Nathalie; Huang, Xaiohong; Gencer, Selin; Coen, Muireann; Tranah, Thomas Henry; Wendon, Julia Alexis; Bruce, Kenneth D.; Le Chatelier, Emmanuelle; Ehrlich, Stanislav Dusko; Edwards, Lindsey Ann; Shoaie, Saeed; Shawcross, Debbie Lindsay
Optimization of an Imidazo[1,2-a]pyridine Series to Afford Highly Selective Type I1/2 Dual Mer/Axl Kinase Inhibitors with In Vivo Efficacy
JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2021-09-0319
PRE
McCoull, William; Boyd, Scott; Brown, Martin R.; Coen, Muireann; Collingwood, Olga; Davies, Nichola L.; Doherty, Ann; Fairley, Gary; Goldberg, Kristin; Hardaker, Elizabeth; He, Guang; Hennessy, Edward J.; Hopcroft, Philip; Hodgson, George; Jackson, Anne; Jiang, Xiefeng; Karmokar, Ankur; Laine, Anne-Laure; Lindsay, Nicola; Mao, Yumeng; Markandu, Roshini; McMurray, Lindsay; McLean, Neville; Mooney, Lorraine; Musgrove, Helen; Nissink, J. Willem M.; Pflug, Alexander; Reddy, Venkatesh Pilla; Rawlins, Philip B.; Rivers, Emma; Schimpl, Marianne; Smith, Graham F.; Tentarelli, Sharon; Travers, Jon; Troup, Robert, I; Walton, Josephine; Wang, Cheng; Wilkinson, Stephen; Williamson, Beth; Winter-Holt, Jon; Yang, Dejian; Zheng, Yuting; Zhu, Qianxiu; Smith, Paul D.
Variability of multi-omics profiles in a population-based child cohort

基于人群的儿童队列中多组学概况的变异性

BMC MEDICINE
IF8.3
2021-07-2218
OAAI
Gallego-Pauls, Marta; Hernandez-Ferrer, Carles; Bustamante, Mariona; Basagana, Xavier; Barrera-Gomez, Jose; Lau, Chung-Ho E.; Siskos, Alexandros P.; Vives-Usano, Marta; Ruiz-Arenas, Carlos; Wright, John; Slama, Remy; Heude, Barbara; Casas, Maribel; Grazuleviciene, Regina; Chatzi, Leda; Borras, Eva; Sabido, Eduard; Carracedo, Angel; Estivill, Xavier; Urquiza, Jose; Coen, Muireann; Keun, Hector C.; Gonzalez, Juan R.; Vrijheid, Martine; Maitre, Lea
Dysregulation of the Lysophosphatidylcholine/Autotaxin/Lysophosphatidic Acid Axis in Acute-on-Chronic Liver Failure Is Associated With Mortality and Systemic Inflammation by Lysophosphatidic Acid-Dependent Monocyte Activation
HEPATOLOGY
IF15.8
2021-06-1534
OAAI
Trovato, Francesca M.; Zia, Rabiya; Napoli, Salvatore; Wolfer, Kate; Huang, Xiaohong; Morgan, Phillip E.; Husbyn, Hannah; Elgosbi, Marwa; Lucangeli, Manuele; Miquel, Rosa; Wilson, Ian; Heaton, Nigel David; Heneghan, Michael A.; Auzinger, Georg; Antoniades, Charalambos G.; Wendon, Julia A.; Patel, Vishal C.; Coen, Muireann; Triantafyllou, Evangelos; McPhail, Mark J.
In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children

在子宫内和儿童时期暴露于烟草烟雾和儿童的多层分子特征

BMC MEDICINE
IF8.3
2020-08-1925
OAAI
Vives-Usano, Marta; Hernandez-Ferrer, Carles; Maitre, Lea; Ruiz-Arenas, Carlos; Andrusaityte, Sandra; Borras, Eva; Carracedo, Angel; Casas, Maribel; Chatzi, Leda; Coen, Muireann; Estivill, Xavier; Gonzalez, Juan R.; Grazuleviciene, Regina; Gutzkow, Kristine B.; Keun, Hector C.; Lau, Chung-Ho E.; Cadiou, Solene; Lepeule, Johanna; Mason, Dan; Quintela, Ines; Robinson, Oliver; Sabido, Eduard; Santorelli, Gillian; Schwarze, Per E.; Siskos, Alexandros P.; Slama, Remy; Vafeiadi, Marina; Marti, Eulalia; Vrijheid, Martine; Bustamante, Mariona
A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat urine
JOURNAL OF CHROMATOGRAPHY A
IF4
2019-09-0140
OAAI
Nye, Leanne C.; Williams, Jonathan P.; Munjoma, Nyasha C.; Letertre, Marine P. M.; Coen, Muireann; Bouwmeester, Robbin; Martens, Lennart; Swann, Jonathan R.; Nicholson, Jeremy K.; Plumb, Robert S.; McCullagh, Michael; Gethings, Lee A.; Lai, Steven; Langridge, James, I; Vissers, Johannes P. C.; Wilson, Ian D.
Autotaxin mediates lipid dysregulation in acute-on-chronic liver failure, promoting persistence of systemic inflammation via lysophosphatidic acid-mediated monocyte activation
JOURNAL OF HEPATOLOGY
IF33
2019-04-010
PREAI
McPhail, Mark J. W.; Trovato, Francesca; Triantafyllou, Evangelos; Zia, Rabiya; Wolfer, Kate; Huang, Xiaohong; Rabinowich, Liane; Patel, Vishal C.; Holmes, Elaine; Heaton, Nigel; Heneghan, Michael; Bernal, William; Auzinger, Georg; Coen, Muireann; Wendon, Julia; Antoniades, Harry

研究方向

暂未获取到该数据
E
Elaine Holmes
H 指数:138论文数:822被引数:8.0万
J
Jeremy K. Nicholson
H 指数:153论文数:1,026被引数:10.5万
J
John C. Lindon
H 指数:104论文数:613被引数:5.2万
H
Hector C. Keun
H 指数:60论文数:372被引数:1.4万
I
Ian D. Wilson
H 指数:82论文数:561被引数:4.0万
L
Léa Maître
H 指数:40论文数:172被引数:4,913
M
Martine Vrijheid
H 指数:106论文数:732被引数:5.1万
O
Oliver Robinson
H 指数:46论文数:184被引数:8,575
R
Rémy Slama
H 指数:79论文数:586被引数:1.9万
M
Maribel Casas
H 指数:61论文数:291被引数:1.3万