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PCSK9 inhibition attenuates alcohol-associated neuronal oxidative stress and cellular injury Wagner, Josephin; Park, Lauren M.; Mukhopadhyay, Partha; Matyas, Csaba; Trojnar, Eszter; Damadzic, Ruslan; Jung, Jeesun; Bell, Andrew S.; Mavromatis, Lucas A.; Hamandi, Ali M.; Rosoff, Daniel B.; Vendruscolo, Leandro F.; Koob, George F.; Pacher, Pal; Lohoff, Falk W. 分享 收藏
A MENDELIAN RANDOMIZATION STUDY OF PRO-PROTEIN CONVERTASE SUBTILISIN KEXIN 9 INHIBITION AND STROKE: EVIDENCE FOR BENEFITS BEYOND LOW-DENSITY LIPOPROTEIN CHOLESTEROL LOWERING Park, Lauren; Rosoff, Daniel; Mavromatis, Lucas; Bell, Andrew; Hamandi, Ali; Jung, Jeesun; Wagner, Josephin; Mukhopadhyay, Partha; Pacher, Pal; Vendruscolo, Leandro; Koob, George; Lohoff, Falk 分享 收藏
PCSK9, A Promising Novel Target for Age-Related Cardiovascular Dysfunction Matyas, Csaba; Trojnar, Eszter; Zhao, Suxian; Arif, Muhammad; Mukhopadhyay, Partha; Kovacs, Attila; Fabian, Alexandra; Tokodi, Marton; Bagyura, Zsolt; Merkely, Bela; Kohidai, Laszlo; Lajko, Eszter; Takacs, Angela; He, Yong; Gao, Bin; Paloczi, Janos; Lohoff, Falk W.; Hasko, Gyorgy; Ding, Wen-Xing; Pacher, Pal 分享 收藏
Data-driven transcriptomics analysis identifies PCSK9 as a novel key regulator in liver aging Arif, Muhammad; Matyas, Csaba; Mukhopadhyay, Partha; Yokus, Burhan; Trojnar, Eszter; Paloczi, Janos; Paes-Leme, Bruno; Zhao, Suxian; Lohoff, Falk W.; Hasko, Gyorgy; Pacher, Pal 分享 收藏
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Execution of Superoxide-Induced Cell Death by the Proapoptotic Bcl-2-Related Proteins Bid and Bak 促凋亡Bcl-2-Related蛋白Bid和Bak执行超氧化物诱导的细胞死亡 Madesh, Muniswamy; Zong, Wei-Xing; Hawkins, Brian J.; Ramasamy, Subbiah; Venkatachalam, Thilagavathi; Mukhopadhyay, Partha; Doonan, Patrick J.; Irrinki, Krishna M.; Rajesh, Mohanraj; Pacher, Pal; Thompson, Craig B. 分享 收藏
Structural basis of selective cannabinoid CB2 receptor activation Li, Xiaoting; Chang, Hao; Bouma, Jara; de Paus, Laura V.; Mukhopadhyay, Partha; Paloczi, Janos; Mustafa, Mohammed; van der Horst, Cas; Kumar, Sanjay Sunil; Wu, Lijie; Yu, Yanan; van den Berg, Richard J. B. H. N.; Janssen, Antonius P. A.; Lichtman, Aron; Liu, Zhi-Jie; Pacher, Pal; van der Stelt, Mario; Heitman, Laura H.; Hua, Tian 分享 收藏
Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis (Apr, 10.1007/s11357-022-00565-9, 2022) 大麻素受体2激活减轻糖尿病诱导的心功能障碍，炎症，氧化应激和纤维化 (4月，10.1007/s11357-022-00565-9，2022) Rajesh, Mohanraj; Mukhopadhyay, Partha; Batkai, Sandor; Arif, Muhammad; Varga, Zoltan V.; Matyas, Csaba; Paloczi, Janos; Lehocki, Andrea; Hasko, Gyorgy; Pacher, Pal 分享 收藏
Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis 大麻素受体2激活可减轻糖尿病诱导的心功能障碍，炎症，氧化应激和纤维化 Rajesh, Mohanraj; Mukhopadhyay, Partha; Batkai, Sandor; Arif, Muhammad; Varga, Zoltan V.; Matyas, Csaba; Paloczi, Janos; Lehocki, Andrea; Hasko, Gyorgy; Pacher, Pal 分享 收藏
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Interplay of Liver-Heart Inflammatory Axis and Cannabinoid 2 Receptor Signaling in an Experimental Model of Hepatic Cardiomyopathy 肝心肌病实验模型中肝心炎性轴和大麻素2受体信号的相互作用 Matyas, Csaba; Erdelyi, Katalin; Trojnar, Eszter; Zhao, Suxian; Varga, Zoltan V.; Paloczi, Janos; Mukhopadhyay, Partha; Nemeth, Balazs T.; Hasko, Gyorgy; Cinar, Resat; Rodrigues, Robim M.; Ahmed, Yeni Ait; Gao, Bin; Pacher, Pal 分享 收藏
PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease 抑制PCSK9作为酒精性肝病治疗的新靶点 Lee, Ji Soo; Mukhopadhyay, Partha; Matyas, Csaba; Trojnar, Eszter; Paloczi, Janos; Yang, Yuan Ru; Blank, Brandon A.; Savage, Cody; Sorokin, Alexander V.; Mehta, Nehal N.; Vendruscolo, Janaina C. M.; Koob, George F.; Vendruscolo, Leandro F.; Pacher, Pal; Lohoff, Falk W. 分享 收藏
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Cannabidiol attenuates alcohol-induced liver steatosis, metabolic dysregulation, inflammation and neutrophil-mediated injury Wang, Yuping; Mukhopadhyay, Partha; Cao, Zongxian; Wang, Hua; Feng, Dechun; Hasko, Gyorgy; Mechoulam, Raphael; Gao, Bin; Pacher, Pal 分享 收藏
Inflammation Is Independent of Steatosis in a Murine Model of Steatohepatitis Wang, Wei; Xu, Ming-Jiang; Cai, Yan; Zhou, Zhou; Cao, Haixia; Mukhopadhyay, Partha; Pacher, Pal; Zheng, Shusen; Gonzalez, Frank J.; Gao, Bin 分享 收藏
Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression 衰老通过下调sirtuin 1表达加重小鼠酒精性肝损伤和纤维化 Ramirez, Teresa; Li, Yong-Mei; Yin, Shi; Xu, Ming-Jiang; Feng, Dechun; Zhou, Zhou; Zang, Mengwei; Mukhopadhyay, Partha; Varga, Zoltan V.; Pacher, Pal; Gao, Bin; Wang, Hua 分享 收藏
PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis Mukhopadhyay, Partha; Horvath, Bela; Rajesh, Mohanraj; Varga, Zoltan V.; Gariani, Karim; Ryu, Dongryeol; Cao, Zongxian; Holovac, Eileen; Park, Ogyi; Zhou, Zhou; Xu, Ming-Jiang; Wang, Wei; Godlewski, Grzegorz; Paloczi, Janos; Nemeth, Balazs Tamas; Persidsky, Yuri; Liaudet, Lucas; Hasko, Gyorgy; Bai, Peter; Boulares, A. Hamid; Auwerx, Johan; Gao, Bin; Pacher, Pal 分享 收藏
A2B adenosine receptor antagonists: Design, synthesis and biological evaluation of novel xanthine derivatives Basu, Sujay; Barawkar, Dinesh A.; Ramdas, Vidya; Waman, Yogesh; Patel, Meena; Panmand, Anil; Kumar, Santosh; Thorat, Sachin; Bonagiri, Rajesh; Jadhav, Dilip; Mukhopadhyay, Partha; Prasad, Vandna; Reddy, B. Srinivasa; Goswami, Arnab; Chaturvedi, Sandhya; Menon, Suraj; Quraishi, Azfar; Ghosh, Indraneel; Dusange, Sushant; Paliwal, Shalini; Kulkarni, Abhay; Karande, Vikas; Thakre, Rhishikesh; Bedse, Gaurav; Rouduri, Sreekanth; Gundu, Jayasagar; Palle, Venkata P.; Chugh, Anita; Mookhtiar, Kasim A. 分享 收藏
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