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Nathalie Janel

universite paris cite

H指数:33

被引数:4,480

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Enhancing virtual screening of cystathionine β-synthase inhibitors: benchmarking target-specific machine-learning scoring functions against state-of-the-art AI docking and co-folding approaches

增强胱硫醚β-合成酶抑制剂的虚拟筛选：将目标特异性机器学习评分函数与最先进的AI对接和共折叠方法进行基准测试

Journal of Cheminformatics

IF5.7

2026-07-180

OA

Pre-Implantation factor (PIF) restores working memory and promotes microglial ramification in the adult Dp(16)1Yey mouse model of Down syndrome

胚胎植入前因子（PIF）可恢复成年Down综合征Dp(16)1Yey小鼠模型的作业记忆，并促进小胶质细胞的分支。

European Journal of Pharmacology

IF4.7

2025-10-280

OAAI

Beta cell function and global glucose metabolism are impaired in Dp(16)1Yey mouse model of Down syndrome

DIABETES OBESITY & METABOLISM

IF5.7

2025-01-130

PRE

Prenatal treatment with preimplantation factor improves early postnatal neurogenesis and cognitive impairments in a mouse model of Down syndrome

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2024-05-130

OAAI

EGCG-like non-competitive inhibitor of DYRK1A rescues cognitive defect in a down syndrome model

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

IF5.9

2024-02-016

PRE

Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome

IF3.7

2023-12-080

PRE

Exploring the link between hedonic overeating and prefrontal cortex dysfunction in the Ts65Dn trisomic mouse model

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2023-11-211

OA

Safety and preliminary efficacy on cognitive performance and adaptive functionality of epigallocatechin gallate (EGCG) in children with Down syndrome. A randomized phase Ib clinical trial (PERSEUS study)

GENETICS IN MEDICINE

IF6.2

2022-10-0113

OA

Cerebral Phospho-Tau Acts Synergistically with Soluble Aβ42 Leading to Mild Cognitive Impairment in AAV-AD Rats

JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE

IF7.8

2022-07-017

OAAI

DYRK1A and Activity-Dependent Neuroprotective Protein Comparative Diagnosis Interest in Cerebrospinal Fluid and Plasma in the Context of Alzheimer-Related Cognitive Impairment in Down Syndrome Patients

IF3.9

2022-06-103

OAAI

Homocysteine Metabolism Pathway Is Involved in the Control of Glucose Homeostasis: A Cystathionine Beta Synthase Deficiency Study in Mouse

IF5.2

2022-05-2510

OAAI

Catechins as a Potential Dietary Supplementation in Prevention of Comorbidities Linked with Down Syndrome

IF5

2022-05-124

OAAI

Metabolic Diseases and Down Syndrome: How Are They Linked Together?

IF3.9

2021-02-2239

OAAI

COVID-19 and Down's syndrome: are we heading for a disaster?

EUROPEAN JOURNAL OF HUMAN GENETICS

IF4.6

2020-07-208

OAAI

Down syndrome and infertility: what support should we provide?

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

IF2.7

2019-05-0925

OAAI

Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2019-03-1834

OAAI

Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models

SCIENTIFIC REPORTS

IF3.9

2019-03-0837

OAAI

Homocysteine-lowering gene therapy rescues signaling pathways in brain of mice with intermediate hyperhomocysteinemia

IF11.9

2018-10-0118

OAAI

Increased levels of inflammatory plasma markers and obesity risk in a mouse model of Down syndrome (vol 114, pg 122, 2018)

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2018-04-010

PREAI

Increased levels of inflammatory plasma markers and obesity risk in a mouse model of Down syndrome

FREE RADICAL BIOLOGY AND MEDICINE

IF8.2

2018-01-0121

OAAI