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J

Julien Dairou

université parís cité
H指数:34
被引数:4,333

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Enhancing virtual screening of cystathionine β-synthase inhibitors: benchmarking target-specific machine-learning scoring functions against state-of-the-art AI docking and co-folding approaches

增强胱硫醚β-合成酶抑制剂的虚拟筛选：将目标特异性机器学习评分函数与最先进的AI对接和共折叠方法进行基准测试

Journal of Cheminformatics
IF5.7
2026-07-180
OA
Cao-Minh Truong; Van-Thinh To; Nathalie Janel; Julien Dairou; Pedro J. Ballester; Olivier Taboureau; Viet-Khoa Tran-Nguyen
Mapping the Brain Interaction Network of the Dual-Specificity; Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography

利用亲和层析技术研究被Leucettinib-21靶向的双特异性酪氨酸磷酸化调控激酶1A（DYRK1A）的大脑相互作用网络图谱

ACS Pharmacology & Translational Science
IF3.7
2026-04-150
PRE
Emmanuel Deau; Coralie Simon; Gaëlle Hogrel; Julien Caillette; Julien Dairou; Yann Herault; Bastien Morlet; Yoshihiko Miyata; Laurent Meijer; Mattias F. Lindberg
Molecular and cellular effects of hydroxy-1,4 naphthoquinones used in dermatological and cosmetic applications on human protein tyrosine phosphatase PTP1B in human keratinocytes

羟基-1,4-萘醌类化合物在皮肤病学和化妆品应用中对人角化细胞中蛋白酪氨酸磷酸酶PTP1B的分子和细胞效应

Molecular Pharmacology
IF3
2025-05-230
PRE
Tessa Arnaud; Christina Michail; Joséphine Gudin de Vallerin; Huicong Liang; Ximing Xu; Julien Dairou; Kevin Cariou; Jean-Marie Dupret; Mireille Viguier; Fernando Rodrigues-Lima; Frédérique Deshayes
Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice
NATURE COMMUNICATIONS
IF15.7
2024-07-290
OAAI
Chajadine, Mouna; Laurans, Ludivine; Radecke, Tobias; Mouttoulingam, Nirmala; Al-Rifai, Rida; Bacquer, Emilie; Delaroque, Clara; Rytter, Heloise; Bredon, Marius; Knosp, Camille; Vilar, Jose; Fontaine, Coralie; Suffee, Nadine; Vandestienne, Marie; Esposito, Bruno; Dairou, Julien; Launay, Jean Marie; Callebert, Jacques; Tedgui, Alain; Ait-Oufella, Hafid; Sokol, Harry; Chassaing, Benoit; Taleb, Soraya
PIK3CA inhibition in models of proliferative glomerulonephritis and lupus nephritis
JOURNAL OF CLINICAL INVESTIGATION
IF13.6
2024-06-062
OAAI
Yamaguchi, Junna; Isnard, Pierre; Robil, Noemie; de la Grange, Pierre; Hoguin, Clement; Schmitt, Alain; Hummel, Aurelie; Megret, Jerome; Goudin, Nicolas; Luka, Marine; Menager, Mickael M.; Masson, Cecile; Zarhrate, Mohammed; Bole-Feysot, Christine; Janiszewska, Michalina; Polyak, Kornelia; Dairou, Julien; Baldassari, Sara; Baulac, Stephanie; Broissand, Christine; Legendre, Christophe; Terzi, Fabiola; Canaud, Guillaume
MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes
NATURE CELL BIOLOGY
IF19.1
2024-06-050
OAAI
Jungnickel, Katharina Esther Julia; Guelle, Oceane; Iguchi, Miharu; Dong, Wentao; Kotov, Vadim; Gabriel, Florian; Debacker, Cecile; Dairou, Julien; McCort-Tranchepain, Isabelle; Laqtom, Nouf N.; Chan, Sze Ham; Ejima, Akika; Sato, Kenji; Massa Lopez, David; Saftig, Paul; Mehdipour, Ahmad Reza; Abu-Remaileh, Monther; Gasnier, Bruno; Loew, Christian; Damme, Markus
Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate

唐氏综合症和阿尔茨海默氏病候选药物Leucettinib-21的化学，生化，细胞和生理特征

JOURNAL OF MEDICINAL CHEMISTRY
IF6.8
2023-12-057
OA
Lindberg, Mattias F.; Deau, Emmanuel; Miege, Frederic; Greverie, Marie; Roche, Didier; George, Nicolas; George, Pascal; Merlet, Laura; Gavard, Julie; Brugman, Sander J. T.; Aret, Edwin; Tinnemans, Paul; de Gelder, Rene; Sadownik, Jan; Verhofstad, Eva; Sleegers, Dennis; Santangelo, Sara; Dairou, Julien; Fernandez-Blanco, Alvaro; Dierssen, Mara; Kraemer, Andreas; Knapp, Stefan; Meijer, Laurent
PIK3CA gain-of-function mutation in adipose tissue induces metabolic reprogramming with Warburg-like effect and severe endocrine disruption
SCIENCE ADVANCES
IF12.5
2022-12-0913
OAAI
Ladraa, Sophia; Zerbib, Lola; Bayard, Charles; Fraissenon, Antoine; Venot, Quitterie; Morin, Gabriel; Garneau, Alexandre P.; Isnard, Pierre; Chapelle, Celia; Hoguin, Clement; Fraitag, Sylvie; Duong, Jean-Paul; Guibaud, Laurent; Besancon, Alix; Kaltenbach, Sophie; Villarese, Patrick; Asnafi, Vahid; Broissand, Christine; Goudin, Nicolas; Dussiot, Michael; Nemazanyy, Ivan; Viel, Thomas; Autret, Gwennhael; Cruciani-Guglielmacci, Celine; Denom, Jessica; Bruneau, Julie; Tavitian, Bertrand; Legendre, Christophe; Dairou, Julien; Lacorte, Jean-Marc; Levy, Pacifique; Pende, Mario; Polak, Michel; Canaud, Guillaume

研究方向

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F
Fernando Rodrigues‐Lima
H 指数:37论文数:252被引数:3,930
J
Jean‐Marie Dupret
H 指数:30论文数:235被引数:2,929
N
Nathalie Janel
H 指数:33论文数:129被引数:4,468
C
Chr̀istophe Magnan
H 指数:57论文数:382被引数:1.3万
F
Florent Busi
H 指数:15论文数:64被引数:632
C
Claude Rouch
H 指数:24论文数:76被引数:1,671
B
B. Pluvinage
H 指数:23论文数:81被引数:1,356
N
Nilusha Ragunathan
H 指数:6论文数:13被引数:138
C
Céline Cruciani‐Guglielmacci
H 指数:30论文数:124被引数:2,847
L
Linh‐Chi Bui
H 指数:16论文数:52被引数:1,207