Bas van Steensel - Publications, H-index & Citations

Bas van Steensel

Oncode Institute

75H指数

273论文数

3.2W被引数

收录论文 84

发表时间

Systematic comparison of estimates of transcription factor activity by ATAC-seq and multiplexed reporter assays ATAC-seq与多重报告基因测定法对转录因子活性估计的系统比较

Molecular Systems Biology

IF7.7

2026-08-17

OAAI

Max Trauernicht; Vinícius H Franceschini-Santos; Hatice Yücel; Teodora Filipovska; Bas van Steensel

Regulatory grammar in human promoters uncovered by MPRA-based deep learning 基于MPRA的深度学习发现的人类促进者中的调节语法

Nature

IF48.5

2026-02-04

OAAI

Lucía Barbadilla-Martínez; Noud Klaassen; Vinícius H. Franceschini-Santos; Jérémie Breda; Hatice Yücel; Miguel Hernández-Quiles; Tijs van Lieshout; Carlos G. Urzua Traslaviña; Minh Chau Luong Boi; Maryam Akbarzadeh; Celia Hermana-Garcia-Agullo; Sebastian Gregoricchio; Marcel de Haas; Roy Straver; Sarah Derks; Wilbert Zwart; Emile Voest; Lude Franke; Michiel Vermeulen; Jeroen de Ridder; Bas van Steensel

An integrated view of the structure and function of the human 4D nucleome 人类4D核体结构与功能的综合视图

Nature

IF48.5

2025-12-17

OAAI

Job Dekker; Betul Akgol Oksuz; Yang Zhang; Ye Wang; Miriam K. Minsk; Shuzhen Kuang; Liyan Yang; Johan H. Gibcus; Nils Krietenstein; Oliver J. Rando; Jie Xu; Derek H. Janssens; Steven Henikoff; Alexander Kukalev; Willemin Andréa; Warren Winick-Ng; Rieke Kempfer; Ana Pombo; Miao Yu; Pradeep Kumar; Liguo Zhang; Andrew S. Belmont; Takayo Sasaki; Tom van Schaik; Laura Brueckner; Daan Peric-Hupkes; Bas van Steensel; Ping Wang; Haoxi Chai; Minji Kim; Yijun Ruan; Ran Zhang; Sofia A. Quinodoz; Prashant Bhat; Mitchell Guttman; Wenxin Zhao; Shu Chien; Yuan Liu; Sergey V. Venev; Dariusz Plewczynski; Ibai Irastorza Azcarate; Dominik Szabó; Christoph J. Thieme; Teresa Szczepińska; Mateusz Chiliński; Kaustav Sengupta; Mattia Conte; Andrea Esposito; Alex Abraham; Ruochi Zhang; Yuchuan Wang; Xingzhao Wen; Qiuyang Wu; Yang Yang; Jie Liu; Lorenzo Boninsegna; Asli Yildirim; Yuxiang Zhan; Andrea Maria Chiariello; Simona Bianco; Lindsay Lee; Ming Hu; Yun Li; R. Jordan Barnett; Ashley L. Cook; Daniel J. Emerson; Claire Marchal; Peiyao Zhao; Peter J. Park; Burak H. Alver; Andrew J. Schroeder; Rahi Navelkar; Clara Bakker; William Ronchetti; Shannon Ehmsen; Alexander D. Veit; Nils Gehlenborg; Ting Wang; Daofeng Li; Xiaotao Wang; Mario Nicodemi; Bing Ren; Sheng Zhong; Jennifer E. Phillips-Cremins; David M. Gilbert; Katherine S. Pollard; Frank Alber; Jian Ma; William S. Noble; Feng Yue

Coordinated control of genome-nuclear lamina interactions by topoisomerase 2B and lamin B receptor 拓扑异构酶2B和层粘连蛋白B受体对基因组-核膜蛋白骨架相互作用的协同调控

NUCLEIC ACIDS RESEARCH

IF13.1

2025-10-14

PREAI

van Schaik, Tom; Magnitov, Mikhail; de Haas, Marcel; Breda, Jeremie; de Wit, Elzo; Manjon, Anna G.; Medema, Rene H.; Gothe, Henrike Johanna; Roukos, Vassilis; Buckle, Adam J.; Naughton, Catherine; Gilbert, Nick; van Steensel, Bas; Manzo, Stefano G.

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene 基因组位点的功能图谱揭示了增强子被其靶基因的约束。

Science

IF45.8

2025-09-18

OAAI

Mathias Eder; Christina J. I. Moene; Lise Dauban; Mikhail Magnitov; Jamie Drayton; Marcel de Haas; Christ Leemans; Martijn Verkuilen; Elzo de Wit; Anders S. Hansen; Bas van Steensel

Interactions between the genome and the nuclear lamina are multivalent and cooperative 基因组与核纤层的相互作用是多价且协同的。

Nature Structural & Molecular Biology

IF10.1

2025-09-01

OAAI

Lise Dauban; Mathias Eder; Marcel de Haas; Vinícius H. Franceschini-Santos; J. Omar Yañez-Cuna; Moreno Martinovic; Tom van Schaik; Christ Leemans; Hans Teunissen; Koen Rademaker; Miguel Martinez Ara; Martijn Verkuilen; Elzo de Wit; Bas van Steensel

Protocol Protocol for multiplexed transcription factor activity detection using optimized barcoded reporters and an automated computational pipeline 协议：用于优化条形码报告子和自动化计算流程的多路转录因子活性检测协议

STAR PROTOCOLS

IF1.3

2025-09-01

OAAI

Trauernicht, Max; Franceschini-Santos, Vinicius H.; Yucel, Hatice; van Steensel, Bas

Predicting gene expression from DNA sequence using deep learning models 基于深度学习模型的DNA序列基因表达预测

Nature Reviews Genetics

IF52

2025-05-13

PREAI

Lucía Barbadilla-Martínez; Noud Klaassen; Bas van Steensel; Jeroen de Ridder

Large-scale analysis of the integration of enhancer-enhancer signals by promoters 启动子对增强子-增强子信号整合的大规模分析

ELIFE

IF0

2024-10-28

OAAI

Martinez-Ara, Miguel; Comoglio, Federico; van Steensel, Bas

Chromatin protein complexes involved in gene repression in lamina-associated domains 染色质蛋白复合物参与层相关结构域的基因抑制

EMBO JOURNAL

IF8.3

2024-09-25

OAAI

Manzo, Stefano G.; Mazouzi, Abdelghani; Leemans, Christ; van Schaik, Tom; Neyazi, Nadia; van Ruiten, Marjon S.; Rowland, Benjamin D.; Brummelkamp, Thijn R.; van Steensel, Bas

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types

COMMUNICATIONS BIOLOGY

IF5.1

2024-09-13

OAAI

Kumar, Pradeep; Gholamalamdari, Omid; Zhang, Yang; Zhang, Liguo; Vertii, Anastassiia; van Schaik, Tom; Peric-Hupkes, Daan; Sasaki, Takayo; Gilbert, David M.; van Steensel, Bas; Ma, Jian; Kaufman, Paul D.; Belmont, Andrew S.

Machine learning prediction of prime editing efficiency across diverse chromatin contexts (21 Jun, 10.1038/s41587-024-02268-2, 2024)

NATURE BIOTECHNOLOGY

IF41.7

2024-08-12

OAAI

Mathis, Nicolas; Allam, Ahmed; Talas, Andras; Kissling, Lucas; Benvenuto, Elena; Schmidheini, Lukas; Schep, Ruben; Damodharan, Tanav; Balazs, Zsolt; Janjuha, Sharan; Ioannidi, Eleonora I.; Boeck, Desiree; van Steensel, Bas; Krauthammer, Michael; Schwank, Gerald

Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing 表观遗传药物对CRISPR-Cas9编辑的染色质上下文依赖效应

NUCLEIC ACIDS RESEARCH

IF13.1

2024-07-02

OAAI

Schep, Ruben; Trauernicht, Max; Vergara, Xabier; Friskes, Anoek; Morris, Ben; Gregoricchio, Sebastian; Manzo, Stefano G.; Zwart, Wilbert; Beijersbergen, Roderick L.; Medema, Rene H.; van Steensel, Bas

Widespread chromatin context-dependencies of DNA double-strand break repair proteins

NATURE COMMUNICATIONS

IF15.7

2024-06-22

OAAI

Vergara, Xabier; Manjon, Anna G.; de Haas, Marcel; Morris, Ben; Schep, Ruben; Leemans, Christ; Friskes, Anoek; Beijersbergen, Roderick L.; Sanders, Mathijs A.; Medema, Rene H.; van Steensel, Bas

Machine learning prediction of prime editing efficiency across diverse chromatin contexts

NATURE BIOTECHNOLOGY

IF41.7

2024-06-21

PREAI

Mathis, Nicolas; Allam, Ahmed; Talas, Andras; Kissling, Lucas; Benvenuto, Elena; Schmidheini, Lukas; Schep, Ruben; Damodharan, Tanav; Balazs, Zsolt; Janjuha, Sharan; Ioannidi, Eleonora I.; Bock, Desiree; van Steensel, Bas; Krauthammer, Michael; Schwank, Gerald

Perturbations in 3D genome organization can promote acquired drug resistance

CELL REPORTS

IF6.9

2023-10-01

OAAI

Manjon, Anna G.; Manzo, Stefano Giustino; Prekovic, Stefan; Potgeter, Leon; Schaik, Tom van; Liu, Ning Qing; Flach, Koen; Peric-Hupkes, Daniel; Joosten, Stacey; Teunissen, Hans; Friskes, Anoek; Ilic, Mila; Hintzen, Dorine; Franceschini-Santos, Vinicius H.; Zwart, Wilbert; de Wit, Elzo; van Steensel, Bas; Medema, Rene H.

Optimisation of TP53 reporters by systematic dissection of synthetic TP53 response elements 通过系统解剖合成TP53反应元件优化TP53报告子

NUCLEIC ACIDS RESEARCH

IF13.1

2023-08-31

OAAI

Trauernicht, Max; Rastogi, Chaitanya; Manzo, Stefano G.; Bussemaker, Harmen J.; van Steensel, Bas

Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR 使用CISSECTOR在全基因组范围内定义启动子活性的精细结构

NUCLEIC ACIDS RESEARCH

IF13.1

2023-04-04

OAAI

FitzPatrick, Vincent D.; Leemans, Christ; van Arensbergen, Joris; van Steensel, Bas; Bussemaker, Harmen J.