Jason D. Buenrostro - Publications, H-index & Citations

Jason D. Buenrostro

Harvard University

58H指数

183论文数

3.1W被引数

收录论文 64

发表时间

Shaping the future of early-onset colorectal cancer prevention 塑造早发性结直肠癌预防的未来

Nature Reviews Cancer

IF66.8

2026-08-26

PREAI

Ruiyi Tian; Sina Azadnajafabad; Erika A. Waters; Emily P. Balskus; Yasmine Belkaid; Jordana T. Bell; Sarah E. Berry; Jason D. Buenrostro; Curtis Huttenhower; Anisha Patel; Gary J. Patti; Nicola Segata; Bhawna Sirohi; Tim D. Spector; Ömer H. Yilmaz; Andrew T. Chan; Yin Cao

Biological aging and generational shifts in early-onset cancer risk 生物衰老和世代更替在早发性癌症风险中的作用

Nature Medicine

IF50

2026-06-22

OAAI

Ruiyi Tian; Xiaoyu Zong; Duo Ren; Stefani Tica; Daniel Hong; Oluseye Oduyale; Jason D. Buenrostro; Ramaswamy Govindan; Yin Cao

Epigenetic memory of colitis promotes tumour growth 结肠炎的表观遗传记忆促进肿瘤生长

Nature

IF48.5

2026-03-25

OAAI

Surya Nagaraja; Lety Ojeda-Miron; Ruochi Zhang; Ena Oreskovic; Conrad Hock; Yan Hu; Daniel Zeve; Karina Sharma; Roni R. Hyman; Qiming Zhang; Andrew Castillo; David T. Breault; Ömer H. Yilmaz; Jason D. Buenrostro

Adrenergic signaling coordinates distant and local responses to amputation in axolotl 肾上腺素能信号协调墨西哥钝口螈断肢后的远端和局部反应

Cell

IF42.5

2025-10-24

OAAI

Duygu Payzin-Dogru; Tim Froitzheim; Steven J. Blair; Siddhartha G. Jena; Hani Singer; Julia C. Paoli; Ryan T. Kim; Emil Kriukov; Sarah E. Wilson; Renzhi Hou; Aaron M. Savage; Victor Cat; Louis V. Cammarata; S.Y. Celeste Wu; Vivien Bothe; Burcu Erdogan; Shifa Hossain; Noah Lopez; Julia Losner; Juan Velazquez Matos; Sangwon Min; Sebastian Böhm; Anthony E. Striker; Kelly E. Dooling; Adam H. Freedman; Bobby Groves; Benjamin Tajer; Glory Kalu; Eric Wynn; Alan Y.L. Wong; Nadia Fröbisch; Petr Baranov; Maksim V. Plikus; Jason D. Buenrostro; Brian J. Haas; Isaac M. Chiu; Timothy B. Sackton; Jessica L. Whited

scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution scooby: 以单细胞分辨率从DNA序列建模多模式基因组图谱

Nature Methods

IF32.1

2025-10-22

OAAI

Johannes C. Hingerl; Laura D. Martens; Alexander Karollus; Trevor Manz; Jason D. Buenrostro; Fabian J. Theis; Julien Gagneur

Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours 髓系祖细胞失调促进肿瘤中的免疫抑制性巨噬细胞

Nature

IF48.5

2025-09-10

PREAI

Samarth Hegde; Bruno Giotti; Brian Y. Soong; Laszlo Halasz; Jessica Le Berichel; Maximilian M. Schaefer; Benoit Kloeckner; Raphaël Mattiuz; Matthew D. Park; Assaf Magen; Adam Marks; Meriem Belabed; Pauline Hamon; Theodore Chin; Leanna Troncoso; Juliana J. Lee; Kaili Fan; Dughan Ahimovic; Michael J. Bale; Kai Nie; Grace Chung; Darwin D’souza; Krista Angeliadis; Seunghee Kim-Schulze; Raja M. Flores; Andrew J. Kaufman; Florent Ginhoux; Jason D. Buenrostro; Steven Z. Josefowicz; Alexander M. Tsankov; Thomas U. Marron; Sai Ma; Brian D. Brown; Miriam Merad

The Somatic Mosaicism across Human Tissues Network 人体组织网络中的体细胞镶嵌

Nature

IF48.5

2025-07-02

PREAI

Tim H. H. Coorens; Ji Won Oh; Yujin Angelina Choi; Nam Seop Lim; Boxun Zhao; Adam Voshall; Alexej Abyzov; Lucinda Antonacci-Fulton; Samuel Aparicio; Kristin G. Ardlie; Thomas J. Bell; James T. Bennett; Bradley E. Bernstein; Thomas G. Blanchard; Alan P. Boyle; Jason D. Buenrostro; Kathleen H. Burns; Fei Chen; Rui Chen; Sangita Choudhury; Harsha V. Doddapaneni; Evan E. Eichler; Gilad D. Evrony; Melissa A. Faith; Thomas G. Fazzio; Robert S. Fulton; Manuel Garber; Nils Gehlenborg; Soren Germer; Gad Getz; Richard A. Gibbs; Raquel G. Hernandez; Fulai Jin; Jan O. Korbel; Dan A. Landau; Heather A. Lawson; Niall J. Lennon; Heng Li; Yan Li; Po-Ru Loh; Gabor Marth; Michael J. McConnell; Ryan E. Mills; Stephen B. Montgomery; Pradeep Natarajan; Peter J. Park; Rahul Satija; Fritz J. Sedlazeck; Diane D. Shao; Hui Shen; Andrew B. Stergachis; Hunter R. Underhill; Alexander E. Urban; Melissa W. VonDran; Christopher A. Walsh; Ting Wang; Tao P. Wu; Chenghang Zong; Eunjung Alice Lee; Flora M. Vaccarino

Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulation 原位基因组测序扩展将核异常与异常染色质调控联系起来

Science

IF45.8

2025-05-29

PREAI

Ajay S. Labade; Zachary D. Chiang; Caroline Comenho; Paul L. Reginato; Andrew C. Payne; Andrew S. Earl; Rojesh Shrestha; Fabiana M. Duarte; Ehsan Habibi; Ruochi Zhang; George M. Church; Edward S. Boyden; Fei Chen; Jason D. Buenrostro

Unified molecular approach for spatial epigenome, transcriptome, and cell lineages 统一分子方法用于空间表观基因组、转录组和细胞谱系

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2025-04-18

OAAI

Huang, Yung-Hsin; Belk, Julia A.; Zhang, Ruochi; Weiser, Natasha E.; Chiang, Zachary; Jones, Matthew G.; Mischel, Paul S.; Buenrostro, Jason D.

Multi-locus CRISPRi targeting with a single truncated guide RNA 单点多位点CRISPRi靶向，使用单个截短型引导RNA

NATURE COMMUNICATIONS

IF15.7

2025-02-04

OAAI

Moore, Molly M.; Wekhande, Siddarth; Issner, Robbyn; Collins, Alejandro; Cruz, Anna J.; Liu, Yanjing V.; Javed, Nauman; Casani-Galdon, Salvador; Buenrostro, Jason D.; Mattei, Eugenio; Doench, John G.; Bernstein, Bradley E.; Shoresh, Noam; Najm, Fadi J.

Degradation of IKZF1 prevents epigenetic progression of T cell exhaustion in an antigen- specific assay

CELL REPORTS MEDICINE

IF10.6

2024-11-01

OAAI

Tay, Tristan; Bommakanti, Gayathri; Jaensch, Elizabeth; Gorthi, Aparna; Reddy, Iswarya Karapa; Hu, Yan; Zhang, Ruochi; Doshi, Aatman S.; Tan, Sin Lih; Brucklacher-Waldert, Verena; Prickett, Laura; Kurasawa, James; Overstreet, Michael Glen; Criscione, Steven; Buenrostro, Jason Daniel; Mele, Deanna A.

BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells BACH2调节TH17细胞中调节性和促炎性染色质状态的多样化

NATURE IMMUNOLOGY

IF27.6

2024-07-15

PREAI

Thakore, Pratiksha I.; Schnell, Alexandra; Huang, Linglin; Zhao, Maryann; Hou, Yu; Christian, Elena; Zaghouani, Sarah; Wang, Chao; Singh, Vasundhara; Singaraju, Anvita; Krishnan, Rajesh Kumar; Kozoriz, Deneen; Ma, Sai; Sankar, Venkat; Notarbartolo, Samuele; Buenrostro, Jason D.; Sallusto, Federica; Patsopoulos, Nikolaos A.; Rozenblatt-Rosen, Orit; Kuchroo, Vijay K.; Regev, Aviv

Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

NATURE COMMUNICATIONS

IF15.7

2024-05-21

OAAI

Schiroli, Giulia; Kartha, Vinay; Duarte, Fabiana M.; Kristiansen, Trine A.; Mayerhofer, Christina; Shrestha, Rojesh; Earl, Andrew; Hu, Yan; Tay, Tristan; Rhee, Catherine; Buenrostro, Jason D.; Scadden, David T.

Identifying cancer vulnerabilities associated with changes in chromatin accessibility by simultaneously profiling hundreds of cancer cell lines with ATAC-seq

CANCER RESEARCH

IF16.6

2024-04-05

PREAI

Borck, Patricia; Wienand, Kirsty; Duarte, Fabiana; Qin, Alvin; Zhang, Ruochi; Babu, Juliana; Zhang, Simone; Maffa, Samuel; Horlbeck, Max; Shrestha, Rojesh; Dempster, Joshua; Roth, Jennifer; Campbell, Catarina; Buenrostro, Jason; Vazquez, Francisca

Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling (vol 39, pg 451, 2021)大规模并行单细胞线粒体DNA基因分型和染色质谱分析 (第39卷，451页，2021)

NATURE BIOTECHNOLOGY

IF41.7

2023-08-31

OAAI

Lareau, Caleb A.; Ludwig, Leif S.; Muus, Christoph; Gohil, Satyen H.; Zhao, Tongtong; Chiang, Zachary; Pelka, Karin; Verboon, Jeffrey M.; Luo, Wendy; Christian, Elena; Rosebrock, Daniel; Getz, Gad; Boland, Genevieve M.; Chen, Fei; Buenrostro, Jason D.; Hacohen, Nir; Wu, Catherine J.; Aryee, Martin J.; Regev, Aviv; Sankaran, Vijay G.

Systematic benchmarking of single-cell ATAC-sequencing protocols 单细胞ATAC测序方案的系统基准测试

NATURE BIOTECHNOLOGY

IF41.7

2023-08-03

OAAI

De Rop, Florian V.; Hulselmans, Gert; Flerin, Chris; Soler-Vila, Paula; Rafels, Albert; Christiaens, Valerie; Gonzalez-Blas, Carmen Bravo; Marchese, Domenica; Caratu, Ginevra; Poovathingal, Suresh; Rozenblatt-Rosen, Orit; Slyper, Michael; Luo, Wendy; Muus, Christoph; Duarte, Fabiana; Shrestha, Rojesh; Bagdatli, S. Tansu; Corces, M. Ryan; Mamanova, Lira; Knights, Andrew; Meyer, Kerstin B.; Mulqueen, Ryan; Taherinasab, Akram; Maschmeyer, Patrick; Pezoldt, Jörn; Lambert, Camille Lucie Germaine; Iglesias, Marta; Najle, Sebastian R.; Dossani, Zain Y.; Martelotto, Luciano G.; Burkett, Zach; Lebofsky, Ronald; Martin-Subero, Jose Ignacio; Pillai, Satish; Sebe-Pedros, Arnau; Deplancke, Bart; Teichmann, Sarah A.; Ludwig, Leif S.; Braun, Theodore P.; Adey, Andrew C.; Greenleaf, William J.; Buenrostro, Jason D.; Regev, Aviv; Aerts, Stein; Heyn, Holger

Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics

CELL SYSTEMS

IF7.7

2023-06-01

OAAI

Morse, David B.; Michalowski, Aleksandra M.; Ceribelli, Michele; De Jonghe, Joachim; Vias, Maria; Riley, Deanna; Davies-Hill, Theresa; Voss, Ty; Pittaluga, Stefania; Muus, Christoph; Liu, Jiamin; Boyle, Samantha; Weitz, David A.; Brenton, James D.; Buenrostro, Jason D.; Knowles, Tuomas P. J.; Thomas, Craig J.

Photoselective sequencing: microscopically guided genomic measurements with subcellular resolution

NATURE METHODS

IF32.1

2023-04-27

OAAI

Mangiameli, Sarah M.; Chen, Haiqi; Earl, Andrew S.; Dobkin, Julie A.; Lesman, Daniel; Buenrostro, Jason D.; Chen, Fei

Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens

MOLECULAR CELL

IF16.6

2023-04-01

OAAI

Otto, Jordan E.; Ursu, Oana; Wu, Alexander P.; Winter, Evan B.; Cuoco, Michael S.; Ma, Sai; Qian, Kristin; Michel, Brittany C.; Buenrostro, Jason D.; Berger, Bonnie; Regev, Aviv; Kadoch, Cigall

Functional inference of gene regulation using single-cell multi-omics 基于单细胞多组学的基因调控功能推断

CELL GENOMICS

IF9

2022-09-01

OAAI

Kartha, Vinay K.; Duarte, Fabiana M.; Hu, Yan; Ma, Sai; Chew, Jennifer G.; Lareau, Caleb A.; Earl, Andrew; Burkett, Zach D.; Kohlway, Andrew S.; Lebofsky, Ronald; Buenrostr, Jason D.

研究方向