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I

István Tombácz

University of Pennsylvania
H指数:14
被引数:2,586

个人简介

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教育背景

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工作经历

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荣誉奖项

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Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice
SCIENCE TRANSLATIONAL MEDICINE
IF14.6
2023-03-0847
OA
da Silva, Jamile Ramos; Rodrigues, Karine Bitencourt; Pelegrin, Guilherme Formoso; Sales, Natiely Silva; Muramatsu, Hiromi; Silva, Mariangela de Oliveira; Porchia, Bruna F. M. M.; Moreno, Ana Carolina Ramos; Aps, Luana Raposo M. M.; Venceslau-Carvalho, Alexia Adrianne; Tombacz, Istvan; Fotoran, Wesley Luzetti; Kariko, Katalin; Lin, Paulo J. C.; Tam, Ying K.; Diniz, Mariana de Oliveira; Pardi, Norbert; Ferreira, Luis Carlos de Souza
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses (vol 54, pg 2877, 2021)
IMMUNITY
IF26.3
2022-06-0123
OAAI
Alameh, Mohamad-Gabriel; Tombacz, Istvan; Bettini, Emily; Lederer, Katlyn; Ndeupen, Sonia; Sittplangkoon, Chutamath; Wilmore, Joel R.; Gaudette, Brian T.; Soliman, Ousamah Y.; Pine, Matthew; Hicks, Philip; Manzoni, Tomaz B.; Knox, James J.; Johnson, John L.; Laczko, Dorottya; Muramatsu, Hiromi; Davis, Benjamin; Meng, Wenzhao; Rosenfeld, Aaron M.; Strohmeier, Shirin; Lin, Paulo J. C.; Mui, Barbara L.; Tam, Ying K.; Kariko, Katalin; Jacquet, Alain; Krammer, Florian; Bates, Paul; Cancro, Michael P.; Weissman, Drew; Prak, Eline T. Luning; Allman, David; Igyarto, Botond Z.; Locci, Michela; Pardi, Norbert
CAR T cells produced in vivo to treat cardiac injury

体内产生的CAR T细胞治疗心脏损伤

Science
IF45.8
2022-01-010
OA
Joel G. Rurik; István Tombácz; Amir Yadegari; Pedro O. Méndez Fernández; Swapnil V. Shewale; Li Li; Toru Kimura; Ousamah Younoss Soliman; Tyler Ellis Papp; Ying K. Tam; Barbara L. Mui; Steven Μ. Albelda; Ellen Puré; Carl H. June; Haig K. Aghajanian; Drew Weissman; Hamideh Parhiz; Jonathan A. Epstein
Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

脂质纳米颗粒通过诱导强大的T滤泡辅助细胞和体液反应增强mRNA和蛋白质亚单位疫苗的功效

IMMUNITY
IF26.3
2021-12-01350
OAAI
Alameh, Mohamad-Gabriel; Tombacz, Istvan; Bettini, Emily; Lederer, Katlyn; Sittplangkoon, Chutamath; Wilmore, Joel R.; Gaudette, Brian T.; Soliman, Ousamah Y.; Pine, Matthew; Hicks, Philip; Manzoni, Tomaz B.; Knox, James J.; Johnson, John L.; Laczko, Dorottya; Muramatsu, Hiromi; Davis, Benjamin; Meng, Wenzhao; Rosenfeld, Aaron M.; Strohmeier, Shirin; Lin, Paulo J. C.; Mui, Barbara L.; Tam, Ying K.; Kariko, Katalin; Jacquet, Alain; Krammer, Florian; Bates, Paul; Cancro, Michael P.; Weissman, Drew; Prak, Eline T. Luning; Allman, David; Locci, Michela; Pardi, Norbert
Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates (Dec, 10.1038/s41541-02100307-6, 2020)
NPJ VACCINES
IF6.5
2021-11-060
OAAI
Saunders, Kevin O.; Pardi, Norbert; Parks, Robert; Santra, Sampa; Mu, Zekun; Sutherland, Laura; Scearce, Richard; Barr, Maggie; Eaton, Amanda; Hernandez, Giovanna; Goodman, Derrick; Hogan, Michael J.; Tombacz, Istvan; Gordon, David N.; Rountree, R. Wes; Wang, Yunfei; Lewis, Mark G.; Pierson, Theodore C.; Barbosa, Chris; Tam, Ying; Matyas, Gary R.; Rao, Mangala; Beck, Zoltan; Shen, Xiaoying; Ferrari, Guido; Tomaras, Georgia D.; Montefiori, David C.; Weissman, Drew; Haynes, Barton F.
Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates
NPJ VACCINES
IF6.5
2021-04-0960
OAAI
Saunders, Kevin O.; Pardi, Norbert; Parks, Robert; Santra, Sampa; Mu, Zekun; Sutherland, Laura; Scearce, Richard; Barr, Maggie; Eaton, Amanda; Hernandez, Giovanna; Goodman, Derrick; Hogan, Michael J.; Tombacz, Istvan; Gordon, David N.; Rountree, R. Wes; Wang, Yunfei; Lewis, Mark G.; Pierson, Theodore C.; Barbosa, Chris; Tam, Ying; Shen, Xiaoying; Ferrari, Guido; Tomaras, Georgia D.; Montefiori, David C.; Weissman, Drew; Haynes, Barton F.
A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice
IMMUNITY
IF26.3
2020-10-01264
OAAI
Laczko, Dorottya; Hogan, Michael J.; Toulmin, Sushila A.; Hicks, Philip; Lederer, Katlyn; Gaudette, Brian T.; Castano, Diana; Amanat, Fatima; Muramatsu, Hiromi; Oguin, Thomas H., III; Ojha, Amrita; Zhang, Lizhou; Mu, Zekun; Parks, Robert; Manzoni, Tomaz B.; Roper, Brianne; Strohmeier, Shirin; Tombacz, Istvan; Arwood, Leslee; Nachbagauer, Raffael; Kariko, Katalin; Greenhouse, Jack; Pessaint, Laurent; Porto, Maciel; Putman-Taylor, Tammy; Strasbaugh, Amanda; Campbell, Tracey-Ann; Lin, Paulo J. C.; Tam, Ying K.; Sempowski, Gregory D.; Farzan, Michael; Choe, Hyeryun; Saunders, Kevin O.; Haynes, Barton F.; Andersen, Hanne; Eisenlohr, Laurence C.; Weissman, Drew; Krammer, Florian; Bates, Paul; Allman, David; Locci, Michela; Pardi, Norbert
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier

纳米药物选择性靶向发炎的脑血管以增强血脑屏障

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2020-01-31112
OAAI
Marcos-Contreras, Oscar A.; Greineder, Colin F.; Kiseleva, Raisa Yu; Parhiz, Hamideh; Walsh, Landis R.; Zuluaga-Ramirez, Viviana; Myerson, Jacob W.; Hood, Elizabeth D.; Villa, Carlos H.; Tombacz, Istvan; Pardi, Norbert; Seliga, Alecia; Mui, Barbara L.; Tam, Ying K.; Glassman, Patrick M.; Shuvaev, Vladimir V.; Nong, Jia; Brenner, Jacob S.; Khoshnejad, Makan; Madden, Tom; Weissmann, Drew; Persidsky, Yuri; Muzykantov, Vladimir R.
Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses

核苷修饰的mRNA疫苗可诱导有效的T滤泡辅助和生发中心b细胞反应

JOURNAL OF EXPERIMENTAL MEDICINE
IF10.6
2018-05-08383
OAAI
Pardi, Norbert; Hogan, Michael J.; Naradikian, Martin S.; Parkhouse, Kaela; Cain, Derek W.; Jones, Letitia; Moody, M. Anthony; Verkerke, Hans P.; Myles, Arpita; Willis, Elinor; LaBranche, Celia C.; Montefiori, David C.; Lobby, Jenna L.; Saunders, Kevin O.; Liao, Hua-Xin; Korber, Bette T.; Sutherland, Laura L.; Scearce, Richard M.; Hraber, Peter T.; Tombacz, Istvan; Muramatsu, Hiromi; Ni, Houping; Balikov, Daniel A.; Li, Charles; Mui, Barbara L.; Tam, Ying K.; Krammer, Florian; Kariko, Katalin; Polacino, Patricia; Eisenlohr, Laurence C.; Madden, Thomas D.; Hope, Michael J.; Lewis, Mark G.; Lee, Kelly K.; Hu, Shiu-Lok; Hensley, Scott E.; Cancro, Michael P.; Haynes, Barton F.; Weissman, Drew

研究方向

暂未获取到该数据
N
Norbert Pardi
H 指数:56论文数:177被引数:1.7万
Y
Ying K. Tam
H 指数:62论文数:188被引数:2.0万
D
Drew Weissman
H 指数:86论文数:388被引数:3.9万
H
Hiromi Muramatsu
H 指数:36论文数:134被引数:1.2万
K
Katalin Karikó
H 指数:55论文数:148被引数:2.5万
B
Barbara L. Mui
H 指数:37论文数:61被引数:1.3万
M
Michael J. Hogan
H 指数:43论文数:160被引数:1.2万
B
Barton F. Haynes
H 指数:144论文数:835被引数:7.7万
K
Kevin O. Saunders
H 指数:50论文数:213被引数:9,691
B
Brian T. Gaudette
H 指数:15论文数:52被引数:2,484