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H

Hiromi Muramatsu

University of Pennsylvania
H指数:36
被引数:1.2万

个人简介

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教育背景

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工作经历

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荣誉奖项

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Selective decay of interferon mRNAs controls antiviral immunity and innate memory

干扰素mRNA的选择性降解调控抗病毒免疫和固有记忆

Molecular Cell
IF16.6
2026-09-010
PRE
Braun, Rachel M.; Ferretti, Max B.; Lee, Jae Seung; Miller, Jesse; Castellana, Lauren; Acuna, Jorge; Whig, Kanupriya; Dohnalova, Lenka; Descamps, Helene C.; Huber, Alex S.; Muramatsu, Hiromi; Hewins, Peter; Li, Yue; Bhutda, Smita; Etwebi, Zienab; Dittmar, Mark; Cook, Thomasina; Schultz, David C.; Blackshear, Perry J.; Jurado, Kellie Ann; Thaiss, Christoph A.; Pardi, Norbert; Lynch, Kristen W.; Cherry, Sara
RNA-LNP–mediated in vivo prime editing corrects disease phenotypes in a mouse model of citrullinemia type I

RNA-LNP介导的在体基础编辑纠正了鸟氨酸氨甲酰转移酶缺乏症小鼠模型的疾病表型

Science Translational Medicine
IF14.6
2026-05-130
PRE
András Tálas; Eleonora I. Ioannidi; Yanik Weber; Tatjana Haenggi; Péter István Kulcsár; Nadia Zürcher; Erica Faccin; Woohyun J. Moon; Lucas Kissling; Elina Andrea Villiger; Mai Matsushita; Tanja Rothgangl; Sharan Janjuha; Paulo J. C. Lin; Martin Poms; Hiromi Muramatsu; Máté Vadovics; Andreas Reichmuth; Manfred Kopf; Norbert Pardi; Ying K. Tam; Johannes Häberle; Gerald Schwank
Optimal murine CD4+ T cell priming by mRNA-lipid nanoparticle vaccines requires endogenous antigen processing

通过mRNA-脂质纳米颗粒疫苗引发的最佳鼠CD4 T细胞需要内源性抗原加工

Nature Communications
IF15.7
2026-01-160
OAAI
Julia E. Rood; Suh Kyung Yoon; Mary K. Heard; Stephen D. Carro; Emma J. Hedgepeth; Mary E. O’Mara; Michael J. Hogan; Nhu Le; Hiromi Muramatsu; Kieu Lam; Petra Schreiner; Coral Kasden; Hansell H. Stedman; Ryan A. Langlois; James Heyes; Norbert Pardi; Laurence C. Eisenlohr
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

mRNA疫苗的不同组分协同作用，指导高效的生发中心反应

Cell
IF42.5
2025-12-160
PREAI
Diana Castaño; Emily Bettini; Binod Kumar; Aleksey Chudnovskiy; Anna Siv; Giulia Protti; Sandra Nakadakari-Higa; Simona Ceglia; Nina De Luna; Joy E. Chiu; Katlyn Lederer; Shuk Hang Li; Hassaan Ibrahim; Hiromi Muramatsu; Thandiswa Mdluli; Edit Abraham; Sinem E. Sahingur; Ivan Maillard; Ying K. Tam; Sunny Shin
Lipid Nanoparticle Library Screen Reveals Lymphatic Endothelial Cell-Targeting Lipid Nanoparticle for Delivering Vascular Endothelial Growth Factor C mRNA after Lymphatic Injury

脂质纳米颗粒库筛选揭示一种靶向淋巴内皮细胞的脂质纳米颗粒，用于在淋巴损伤后递送血管内皮生长因子C mRNA

ACS NANO
IF16
2025-11-010
PRE
Michalaki, Eleftheria; Jeong, Kiyoung; Chin, Rachel; Qi, Zhiming; Liebman, Lauren; Gonzalez-Vargas, Yarelis; Echeverri, Elisa Schrader; Paunovska, Kalina; Muramatsu, Hiromi; Pardi, Norbert; Tamburini, Beth Jiron; Jakus, Zoltan; Dahlman, James E.; Dixon, J. Brandon
Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice

计算设计的mRNA启动的蛋白质纳米颗粒免疫原在 mice 中诱导保护性抗体和T细胞应答

Science Translational Medicine
IF14.6
2025-10-150
PRE
Grace G. Hendricks; Lilit Grigoryan; Mary Jane Navarro; Nicholas J. Catanzaro; Miranda L. Hubbard; John M. Powers; Melissa Mattocks; Catherine Treichel; Alexandra C. Walls; Jimin Lee; Daniel Ellis; Jing Yang (John) Wang; Suna Cheng; Marcos C. Miranda; Adian Valdez; Cara W. Chao; Sidney Chan; Christine Men; Max R. Johnson; Samantha K. Zepeda; Sebastian Ols; Harold Hui; Sheng-Yang Wu; Victor Lujan; Hiromi Muramatsu; Paulo J.C. Lin; Molly M.H. Sung; Ying K. Tam; Elizabeth M. Leaf; Norbert Pardi; Ralph S. Baric; Bali Pulendran; David Veesler; Alexandra Schäfer; Neil P. King
mRNA-LNP vaccine encoding the Plasmodium vivax circumsporozoite protein is highly immunogenic and confers protection in mice

编码恶性疟原虫环子孢子蛋白的mRNA-LNP疫苗具有高度免疫原性，并能在小鼠中提供保护。

Molecular Therapy Nucleic Acids
IF6.1
2025-07-300
OAAI
Amporn Limsalakpetch; Utaiwan Kum-Arb; Kosol Yongvanitchit; Rawiwan Im-Erbsin; Ratawan Ubalee; Norman Waters; Brian A. Vesely; Hiromi Muramatsu; Drew Weissman; Ying K. Tam; Shigeto Yoshida; John Adams; Anjali Yadava; Norbert Pardi; Sathit Pichyangkul
Efficacy test of a Mycoplasma hyorhinis mRNA-LNP vaccine candidate

Mycoplasma hyorhinis mRNA-LNP疫苗候选物的效力测试

vaccine
IF2.2
2025-07-030
PRE
Eszter Zsófia Nagy; Levente Szeredi; Hiromi Muramatsu; Noémi Nagy; Dénes Grózner; Zsuzsa Kreizinger; Kinga M. Sulyok; Bandana Pangabam; Lilla Tóth; Rachel H.J. Jun; Dorottya Földi; Enikő Wehmann; Miklós Tenk; Norbert Pardi; Miklós Gyuranecz
Tailoring the adjuvanticity of lipid nanoparticles by PEG lipid ratio and phospholipid modifications

通过PEG脂质比例和磷脂修饰来定制脂质纳米颗粒的佐剂性

Nature Nanotechnology
IF34.9
2025-06-230
PRE
Máté Vadovics; Wenchen Zhao; Emily F. Daley; Kieu Lam; Owen Daly; Khalid Rashid; Hailey R. Lee; Petra Schreiner; Kendall A. Lundgreen; Brian T. Gaudette; Vladimir V. Shuvaev; Evguenia Arguiri; Hiromi Muramatsu; András Sárközy; Thandiswa Mdluli; Junchao Xu; Xuexiang Han; Nina De Luna; Diana Castaño; Emily Bettini; Edit Ábrahám; Zoltan Lipinszki; Giuseppe Carlucci; Avinash Haridas Bansode; Katelyn Nguyen; Thuc M. Le; Tony Luu; Vladimir R. Muzykantov; Paul Bates; David Allman; Michael J. Mitchell; Michela Locci; Caius G. Radu; James Heyes; Norbert Pardi
Treatment of a metabolic liver disease in mice with a transient prime editing approach

使用暂时性碱基编辑方法治疗小鼠的代谢性肝病

NATURE BIOMEDICAL ENGINEERING
IF26.6
2025-05-200
OA
Rothgangl, Tanja; Talas, Andras; Ioannidi, Eleonora I.; Weber, Yanik; Bock, Desiree; Matsushita, Mai; Villiger, Elina Andrea; Schmidheini, Lukas; Moon, Woohyun J.; Lin, Paulo J. C.; Fan, Steven H. Y.; Marquart, Kim F.; Schwerdel, Cornelia; Rimann, Nicole; Faccin, Erica; Villiger, Lukas; Muramatsu, Hiromi; Vadovics, Mate; Cremonesi, Alessio; Kulcsar, Peter Istvan; Thoeny, Beat; Kopf, Manfred; Haberle, Johannes; Pardi, Norbert; Tam, Ying K.; Schwank, Gerald
mRNA-LNP vaccine-induced CD8+T cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies
MOLECULAR THERAPY
IF12
2024-06-013
OAAI
Montoya, Brian; Melo-Silva, Carolina R.; Tang, Lingjuan; Kafle, Samita; Lidskiy, Peter; Bajusz, Csaba; Vadovics, Mate; Muramatsu, Hiromi; Abraham, Edit; Lipinszki, Zoltan; Chatterjee, Debotri; Scher, Gabrielle; Benitez, Juliana; Sung, Molly M. H.; Tam, Ying K.; Catanzaro, Nicholas J.; Schaefer, Alexandra; Andino, Raul; Baric, Ralph S.; Martinez, David R.; Pardi, Norbert; Sigal, Luis J.
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination
NATURE IMMUNOLOGY
IF27.6
2024-03-1411
OAAI
Fumagalli, Valeria; Rava, Micol; Marotta, Davide; Di Lucia, Pietro; Bono, Elisa B.; Giustini, Leonardo; De Leo, Federica; Casalgrandi, Maura; Monteleone, Emanuele; Mouro, Violette; Malpighi, Chiara; Perucchini, Chiara; Grillo, Marta; De Palma, Sara; Donnici, Lorena; Marchese, Silvia; Conti, Matteo; Muramatsu, Hiromi; Perlman, Stanley; Pardi, Norbert; Kuka, Mirela; De Francesco, Raffaele; Bianchi, Marco E.; Guidotti, Luca G.; Iannacone, Matteo

研究方向

暂未获取到该数据
N
Norbert Pardi
H 指数:56论文数:177被引数:1.7万
Y
Ying K. Tam
H 指数:62论文数:188被引数:2.0万
D
Drew Weissman
H 指数:86论文数:388被引数:3.9万
K
Katalin Karikó
H 指数:55论文数:148被引数:2.5万
P
Paulo J.C. Lin
H 指数:36论文数:141被引数:6,620
I
István Tombácz
H 指数:14论文数:21被引数:2,586
F
Florian Krammer
H 指数:117论文数:811被引数:6.3万
M
Máté Vadovics
H 指数:9论文数:21被引数:330
P
Paul Bates
H 指数:53论文数:107被引数:1.3万
M
Michela Locci
H 指数:23论文数:47被引数:4,810