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Y

Ying K. Tam

acuitas therapeutics
H指数:62
被引数:2.0万

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Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies

增强B细胞初始刺激诱导广泛中和HIV-1顶点抗体

Nature
IF48.5
2026-06-300
PRE
Lorie Marchitto; Kshitij Wagh; Ryan S. Roark; Severin Coleon; Hui Li; Ashwin N. Skelly; Michael P. Hogarty; Rumi Habib; Wenge Ding; Kasirajan Ayyanathan; Weimin Liu; Zizhang Sheng; Yicheng Guo; Joena Bal; Lena M. Smith; Laura L. Sutherland; Younghoon Park; Andrew J. Connell; Frederic Bibollet-Ruche; Emily Lewis; Samantha J. Plante; Macy J. Akeley; Jinery Lora; Chengyan Zhao; John W. Carey; Christian L. Martella; Yingying Li; Mary S. Campion; Melinda G. Lituchy; Rebecca A. Osbaldeston; Colette G. Gordon; Amie Albertus; Justin Su; Chiaki Noguchi; Ying K. Tam; Christopher Barbosa; Bo Liang; Khaled Amereh; Xuduo Li; Agnes A. Walsh; Darrell J. Irvine; Raiees Andrabi; Robert J. Edwards; Edward F. Kreider; Drew Weissman; Lawrence Shapiro; Peter D. Kwong; Bette T. Korber; Barton F. Haynes; Kevin O. Saunders; Beatrice H. Hahn; George M. Shaw
RNA-LNP–mediated in vivo prime editing corrects disease phenotypes in a mouse model of citrullinemia type I

RNA-LNP介导的在体基础编辑纠正了鸟氨酸氨甲酰转移酶缺乏症小鼠模型的疾病表型

Science Translational Medicine
IF14.6
2026-05-130
PRE
András Tálas; Eleonora I. Ioannidi; Yanik Weber; Tatjana Haenggi; Péter István Kulcsár; Nadia Zürcher; Erica Faccin; Woohyun J. Moon; Lucas Kissling; Elina Andrea Villiger; Mai Matsushita; Tanja Rothgangl; Sharan Janjuha; Paulo J. C. Lin; Martin Poms; Hiromi Muramatsu; Máté Vadovics; Andreas Reichmuth; Manfred Kopf; Norbert Pardi; Ying K. Tam; Johannes Häberle; Gerald Schwank
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

mRNA疫苗的不同组分协同作用，指导高效的生发中心反应

Cell
IF42.5
2025-12-160
PREAI
Diana Castaño; Emily Bettini; Binod Kumar; Aleksey Chudnovskiy; Anna Siv; Giulia Protti; Sandra Nakadakari-Higa; Simona Ceglia; Nina De Luna; Joy E. Chiu; Katlyn Lederer; Shuk Hang Li; Hassaan Ibrahim; Hiromi Muramatsu; Thandiswa Mdluli; Edit Abraham; Sinem E. Sahingur; Ivan Maillard; Ying K. Tam; Sunny Shin
Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice

计算设计的mRNA启动的蛋白质纳米颗粒免疫原在 mice 中诱导保护性抗体和T细胞应答

Science Translational Medicine
IF14.6
2025-10-150
PRE
Grace G. Hendricks; Lilit Grigoryan; Mary Jane Navarro; Nicholas J. Catanzaro; Miranda L. Hubbard; John M. Powers; Melissa Mattocks; Catherine Treichel; Alexandra C. Walls; Jimin Lee; Daniel Ellis; Jing Yang (John) Wang; Suna Cheng; Marcos C. Miranda; Adian Valdez; Cara W. Chao; Sidney Chan; Christine Men; Max R. Johnson; Samantha K. Zepeda; Sebastian Ols; Harold Hui; Sheng-Yang Wu; Victor Lujan; Hiromi Muramatsu; Paulo J.C. Lin; Molly M.H. Sung; Ying K. Tam; Elizabeth M. Leaf; Norbert Pardi; Ralph S. Baric; Bali Pulendran; David Veesler; Alexandra Schäfer; Neil P. King
Chimeric hemagglutinin-based universal influenza mRNA vaccine induces protective immunity and bone marrow plasma cells in rhesus macaques

基于嵌合血凝素的全能流感mRNA疫苗在恒河猴中诱导保护性免疫和骨髓浆细胞

Cell Reports Medicine
IF10.6
2025-09-250
OAAI
Tiffany M. Styles; Akil Akhtar; Chunyang Gu; Gabriele Neumann; Hiromi Muramatsu; Justine S. McPartlan; Poulami Talukder; Derrik Gratz; Kasey Stokdyk; Hannah L. Turner; James A. Ferguson; Alesandra J. Rodriguez; Madhumathi Loganathan; Benjamin Francis; Anass Abbad; Ghania Chikh; Ying K. Tam; Zhaohui S. Qin; Julianna Han; Juan Manuel Carreño; Andrew B. Ward; Jasdave S. Chahal; Christian W. Mandl; Norbert Pardi; Yoshihiro Kawaoka; Florian Krammer; Rafi Ahmed; Rama R. Amara
mRNA-LNP vaccine encoding the Plasmodium vivax circumsporozoite protein is highly immunogenic and confers protection in mice

编码恶性疟原虫环子孢子蛋白的mRNA-LNP疫苗具有高度免疫原性，并能在小鼠中提供保护。

Molecular Therapy Nucleic Acids
IF6.1
2025-07-300
OAAI
Amporn Limsalakpetch; Utaiwan Kum-Arb; Kosol Yongvanitchit; Rawiwan Im-Erbsin; Ratawan Ubalee; Norman Waters; Brian A. Vesely; Hiromi Muramatsu; Drew Weissman; Ying K. Tam; Shigeto Yoshida; John Adams; Anjali Yadava; Norbert Pardi; Sathit Pichyangkul
mRNA-LNP vaccines against hepatitis B virus induce protective immune responses in preventive and chronic mouse challenge models

mRNA-LNP疫苗在预防性和慢性小鼠挑战模型中诱导保护性免疫反应

Molecular Therapy
IF12
2025-06-140
OAAI
María José Limeres; Rocio Gambaro; Malin Svensson; Silvia Fraude-El Ghazi; Leah Pretsch; Daniel Frank; German A. Islan; Ignacio Rivero Berti; Matthias Bros; Ying K. Tam; Hiromi Muramatsu; Norbert Pardi; Stephan Gehring; Maximiliano L. Cacicedo
An Il12 mRNA-LNP adjuvant enhances mRNA vaccine–induced CD8 T cell responses

一种Il12 mRNA-LNP佐剂增强了mRNA疫苗诱导的CD8 T细胞反应

Science Immunology
IF16.3
2025-06-060
PRE
Emily A. Aunins; Anthony T. Phan; Mohamad-Gabriel Alameh; Garima Dwivedi; Elisa Cruz-Morales; David A. Christian; Ying Tam; Molly E. Bunkofske; Anabel Zabala Peñafiel; Keenan M. O’Dea; Maria Merolle; Colleen Furey; Phillip Scott; Robert H. Vonderheide; Scott E. Hensley; Ross M. Kedl; Drew Weissman; Christopher A. Hunter
Treatment of a metabolic liver disease in mice with a transient prime editing approach

使用暂时性碱基编辑方法治疗小鼠的代谢性肝病

NATURE BIOMEDICAL ENGINEERING
IF26.6
2025-05-200
OA
Rothgangl, Tanja; Talas, Andras; Ioannidi, Eleonora I.; Weber, Yanik; Bock, Desiree; Matsushita, Mai; Villiger, Elina Andrea; Schmidheini, Lukas; Moon, Woohyun J.; Lin, Paulo J. C.; Fan, Steven H. Y.; Marquart, Kim F.; Schwerdel, Cornelia; Rimann, Nicole; Faccin, Erica; Villiger, Lukas; Muramatsu, Hiromi; Vadovics, Mate; Cremonesi, Alessio; Kulcsar, Peter Istvan; Thoeny, Beat; Kopf, Manfred; Haberle, Johannes; Pardi, Norbert; Tam, Ying K.; Schwank, Gerald
Monitoring mRNA vaccine antigen expression in vivo using PET/CT

使用PET/CT监测mRNA疫苗抗原在体内的表达

NATURE COMMUNICATIONS
IF15.7
2025-03-061
OA
Blizard, Gabrielle S.; Dwivedi, Garima; Pan, Yi-Gen; Hou, Catherine; Etersque, Jean M.; Said, Hooda; Chevrier, Anik; Lavertu, Marc; Ni, Houping; Davis, Benjamin; Tam, Ying; Cao, Quy; Mach, Robert H.; Weissman, Drew; Alameh, Mohamad-Gabriel; Sellmyer, Mark A.
Staggered immunization with mRNA vaccines encoding SARS- CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire

编码传染性非典型肺炎CoV-2聚合酶或刺突抗原的mRNA疫苗的交错预防接种扩大了T细胞表位库

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
IF9.1
2024-11-260
OAAI
Abt, Evan R.; Lam, Alex K.; Noguchi, Miyako; Rashid, Khalid; Mclaughlin, Jami; Teng, Pu - Lin; Tran, Wendy; Cheng, Donghui; Nesterenko, Pavlo A.; Mao, Zhiyuan; Creech, Amanda L.; Sojo, Giselle Burton; Jeyachandran, Arjit Vijey; Tam, Ying K.; Henley, Jill E.; Comai, Lucio; Pardi, Norbert; Arumugaswami, Vaithilingaraja; Witte, Owen N.; Radu, Caius G.; Wu, Ting- Ting

研究方向

暂未获取到该数据
D
Drew Weissman
H 指数:86论文数:388被引数:3.8万
N
Norbert Pardi
H 指数:56论文数:177被引数:1.7万
P
Paulo J.C. Lin
H 指数:36论文数:141被引数:6,603
H
Hiromi Muramatsu
H 指数:36论文数:134被引数:1.2万
B
Barbara L. Mui
H 指数:37论文数:61被引数:1.3万
M
Mohamad‐Gabriel Alameh
H 指数:48论文数:173被引数:8,751
M
Michael J. Hope
H 指数:60论文数:152被引数:2.4万
T
Thomas D. Madden
H 指数:39论文数:88被引数:1.3万
I
István Tombácz
H 指数:14论文数:21被引数:2,579
F
Florian Krammer
H 指数:117论文数:811被引数:6.3万