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李哲 封面图

李哲 (Zhe Li)

Sun Yat-Sen University

36H指数
188论文数
4.9K被引数
收录论文 89
发表时间
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An Orally Available Telomeric G-Quadruplex Ligand Induces Telomere Crisis and Dual DNA/RNA-Sensing Innate Immunity for Cancer Therapy一种口服可用的端粒G-四链体配体诱导端粒危机和双DNA/RNA传感固有免疫用于癌症治疗
errJournal of Medicinal Chemistry
IF6.8
err2026-02-13
err0
PREAI
errJiong-Heng Cai; Yao-Hui Shi; Dan-Yan Yang; Wan-Yi Huang; Yang Liu; Li-Ting Zhong; Jun-Jie Zhang; Zhu Gong; Ying-Yue Lu; Jia-Hui Lin; Mao-Lin Li; Zhe Li; Gui-Hong Chai; Tian-Miao Ou; Jia-Heng Tan; Zhi-Shu Huang; Shuo-Bin Chen
err分享
err收藏
ALCHEMD: Bridging Accessibility and Accuracy in Automated Relative Binding Free Energy Workflows
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2025-12-01
err0
PREAI
errLiu, Runduo; Zhong, Yilin; Yao, Yufen; Huang, Wanyi; Li, Zongda; Lu, Yuning; Luo, Hai-Bin; Li, Zhe
err分享
err收藏
Extreme Drought Restructures Floodplain Fish Assemblages Through Trait Convergence and Assembly Mechanism Shifts极端干旱通过性状趋同和组装机制转变重塑洪泛区鱼类群落
errDiversity and Distributions
IF4.2
err2025-11-06
err0
errOAAI
errYunzhe Huang; Huan Zhang; Min Guo; Zhe Li; Geng Huang; Li Wen; Yunliang Li; Yuyu Wang
err分享
err收藏
Adsorption behavior of Se(IV) and Se(VI) on sodium bentonite
errKERNTECHNIK
IF0.9
err2025-11-01
err0
PREAI
errHuang, Cong; Zhao, Qiang; Li, Zhe; Dou, Chenshuo; Su, Xuebin; Hua, Rong
err分享
err收藏
PROCR diminishes the efficacy of radiation by impairing T-cell-mediated antitumour immunityPROCR通过损害T细胞介导的抗肿瘤免疫来降低辐射的疗效。
errNature Communications
IF15.7
err2025-08-04
err0
errOAAI
errWeipeng Chen; Chuqing Zhang; Zhe Li; Zhimin Xu; Cong Ding; Jiawei Wu; Hanmiao Wei; Zhenji Deng; Tingxiang He; Liufen Long; Yanping Mao; Jun Ma; Xiaoyu Liang
err分享
err收藏
Precision-Oriented Theophylline-Platinum(IV) Prodrugs: Eliciting Synthetic Lethality in BRCA1-Deficient Ovarian Cancer with Enhanced Efficacy and Reduced Toxicity In Vitro and In Vivo靶向精度的茶碱-铂(IV)前药：在体内外于BRCA1缺失的卵巢癌中引发合成致死，并增强疗效与降低毒性
errJournal of Medicinal Chemistry
IF6.8
err2025-07-09
err0
PREAI
errXiao-Meng Liu; Zhen-Zhen Zhu; Qing-Tian Li; Zhe Li; Rui Rong; Cheng-Zhi Xie; Xin Qiao; Yu-Kuan Feng; Jing-Yuan Xu
err分享
err收藏
Deciphering Glutaminyl Cyclase Catalytic Pathways Enables Recognition of Anchor Pharmacophores for Inhibitor Discovery解析谷氨酰胺酰环化酶催化通路有助于识别抑制剂发现中的锚定药效基团
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2025-05-14
err0
PREAI
errWu, Jing-Wei; Ning, Xiang-Li; Tang, Biao-Dan; Chen, Yi-Ting; Yang, Zeng-Bao; Meng, Fan-Bo; Zhou, Cong; Yu, Jun-Lin; Li, Rong; Li, Zhe
err分享
err收藏
Plasma metabolites-based drug design: Discovery of novel and highly selective phosphodiesterase 5 inhibitors基于血浆代谢物的药物设计：新型高选择性磷酸二酯酶5抑制剂的发现
errChinese Chemical Letters
IF8.9
err2025-04-22
err0
PREAI
errDeyan Wu; Qingjiang Ma; Yanquan Chen; Guofeng Yang; Fengcai Zhang; Meiyan Jiang; Xue Wang; Xingfu Liu; Qian Zhou; Yi-You Huang; Zhe Li; Hai-Bin Luo
err分享
err收藏
Preimplantation genetic testing for aneuploidy does not benefit couples with male factor infertility植入前非整倍体遗传学检测对男性因素不孕夫妇无益。
errFertility and Sterility
IF7
err2025-02-13
err0
PREAI
errWeilin Wang; Juanjuan Lu; Zhe Li; Wei Zhou; Qian Zhang; Tianxiang Ni; Junhao Yan
err分享
err收藏
Ionic conducting hydrogels as biomedical materials: classification, design strategies, and skin tissue engineering applications离子导电水凝胶作为生物医学材料: 分类，设计策略和皮肤组织工程应用
errJOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
IF3.6
err2024-12-02
err0
PREAI
errZhang, Wanping; Li, Zhe; Zhang, Qianjie; Zheng, Shilian; Zhang, Zijia; Chen, Simin; Wang, Zixin; Zhang, Dongmei
err分享
err收藏
Mediator complex subunit 1 promotes oral squamous cell carcinoma progression by activating MMP9 transcription and suppressing CD8+ T cell antitumor immunity
errJOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
IF12.8
err2024-09-30
err1
errOAAI
errLi, Zhe; Sun, Mengke; Yang, Ruimeng; Wang, Zheng; Zhu, Qianyu; Zhang, Yue; Yang, Haosun; Meng, Zhaosong; Hu, Lizhi; Sui, Lei
err分享
err收藏
Convergence-Adaptive Roundtrip Method Enables Rapid and Accurate FEP Calculations
errJOURNAL OF CHEMICAL THEORY AND COMPUTATION
IF5.5
err2024-09-05
err0
PREAI
errYao, Yufen; Liu, Runduo; Li, Wenchao; Huang, Wanyi; Lai, Yijun; Luo, Hai-Bin; Li, Zhe
err分享
err收藏
Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination
errIMMUNITY
IF26.3
err2024-09-01
err0
errOAAI
errLi, Zhe; Obraztsova, Anna; Shang, Fuwei; Oludada, Opeyemi Ernest; Malapit, Joshua; van Straaten, Monique; Stebbins, Erec; Murugan, Rajagopal; Wardemann, Hedda
err分享
err收藏
The role of Keap1-Nrf2 signaling pathway during the progress and therapy of diabetic retinopathyKeap1-Nrf2信号通路在糖尿病视网膜病变进展及治疗中的作用
errLIFE SCIENCES
IF5.1
err2024-02-01
err6
PREAI
errChen, Jiawen; Wang, Qi; Li, Ruiyan; Li, Zhe; Jiang, Qizhou; Yan, Fangrong; Ye, Junmei
err分享
err收藏
53BP1 loss mediated PARP inhibitor resistance in BRCA1-deficient pancreatic cancer is overcome with immune checkpoint blockade
errCANCER RESEARCH
IF16.6
err2024-01-09
err0
PREAI
errPatterson-Fortin, Jeffrey; Sun, Yajie; Han, Sen; Li, Zhe; Nowicka, Zuzanna; Hirohashi, Yuna; Kilgas, Susan; Yi, Jae Kyo; Spektor, Alexander; Fendler, Wojciech; Konstantinopoulos, Panagiotis; D'Andrea, Alan D.; Chowdhury, Dipanjan
err分享
err收藏
Accelerating and Automating the Free Energy Perturbation Absolute Binding Free Energy Calculation with the RED-E Function
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2023-12-04
err5
PREAI
errLiu, Runduo; Li, Wenchao; Yao, Yufen; Wu, Yinuo; Luo, Hai-Bin; Li, Zhe
err分享
err收藏
HetDDI: a pre-trained heterogeneous graph neural network model for drug-drug interaction prediction
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2023-10-30
err5
errOAAI
errLi, Zhe; Tu, Xinyi; Chen, Yuping; Lin, Wenbin
err分享
err收藏
3D-SMGE: a pipeline for scaffold-based molecular generation and evaluation
errBRIEFINGS IN BIOINFORMATICS
IF7.7
err2023-09-26
err1
PREAI
errXu, Chao; Liu, Runduo; Huang, Shuheng; Li, Wenchao; Li, Zhe; Luo, Hai-Bin
err分享
err收藏
Loss of the adaptor protein Sh3bgrl initiates ovarian fibrosis in zebrafish
errFEBS LETTERS
IF3
err2023-09-20
err0
PREAI
errJin, Ziwei; Wang, Dongxia; Lv, Haimei; Wu, Bo; Li, Zhe; Guo, Xiaoling; Wang, Haihe; Yang, Shulan
err分享
err收藏
Identification of Novel Quinolin-2(1H)-ones as Phosphodiesterase 1 Inhibitors for the Treatment of Inflammatory Bowel Disease
errJOURNAL OF MEDICINAL CHEMISTRY
IF6.8
err2023-08-16
err8
PREAI
errZhang, Bei; Yang, Yi-Yi; Zhao, Zheng-Jiong; Liu, Run-Duo; Feng, Ling-Ling; Jiang, Mei-Yan; Yuan, Yijun; Huang, Shuheng; Li, Zhe; Wang, Quan; Luo, Hai-Bin; Wu, Yinuo
err分享
err收藏

研究方向

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合作学者
合作期刊
G
George D. Yancopoulos
H 指数: 203 · 论文数: 945
F
Fernando J. Martínez
H 指数: 156 · 论文数: 1.3K
S
Stanley B. Prusiner
H 指数: 155 · 论文数: 653
张莉娜 封面图
张莉娜 (Lina Zhang)
H 指数: 126 · 论文数: 1.7K
A
Alan D. D’Andrea
H 指数: 120 · 论文数: 710
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