未登录 Lysosomal lipid peroxidation regulates tumor immunity Bhardwaj, Monika; Lee, Jennifer J.; Versace, Amanda M.; Harper, Sandra L.; Goldman, Aaron R.; Crissey, Mary Ann S.; Jain, Vaibhav; Singh, Mahendra Pal; Vernon, Megane; Aplin, Andrew E.; Lee, Seokwoo; Morita, Masao; Winkler, Jeffrey D.; Liu, Qin; Speicher, David W.; Amaravadi, Ravi K. 分享 收藏
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma (vol 7, e165688, 2022) Sharma, Gaurav; Ojha, Rani; Noguera-Ortega, Estela; Rebecca, Vito W.; Attanasio, John; Liu, Shujing; Piao, Shengfu; Lee, Jennifer J.; Nicastri, Michael C.; Harper, Sandra L.; Ronghe, Amruta; Jain, Vaibhav; Winkler, Jeffrey D.; Speicher, David W.; Mastio, Jerome; Gimotty, Phyllis A.; Xu, Xiaowei; Wherry, E. John; Gabrilovich, Dmitry I.; Amaravadi, Ravi K. 分享 收藏
Targeting acetyl-CoA metabolism attenuates the formation of fear memories through reduced activity-dependent histone acetylation 靶向乙酰辅酶a代谢通过降低活性依赖性组蛋白乙酰化减弱恐惧记忆的形成 Alexander, Desi C.; Corman, Tanya; Mendoza, Mariel; Glass, Andrew; Belity, Tal; Wu, Ranran; Campbell, Rianne R.; Han, Joseph; Keiser, Ashley A.; Winkler, Jeffrey; Wood, Marcelo A.; Kim, Thomas; Garcia, Benjamin A.; Cohen, Hagit; Mews, Philipp; Egervari, Gabor; Berger, Shelley L. 分享 收藏
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SIRT1 is downregulated by autophagy in senescence and ageing SIRT1在衰老和衰老过程中被自噬下调 Xu, Caiyue; Wang, Lu; Fozouni, Parinaz; Evjen, Gry; Chandra, Vemika; Jiang, Jing; Lu, Congcong; Nicastri, Michael; Bretz, Corey; Winkler, Jeffrey D.; Amaravadi, Ravi; Garcia, Benjamin A.; Adams, Peter D.; Ott, Melanie; Tong, Wei; Johansen, Terje; Dou, Zhixun; Berger, Shelley L. 分享 收藏
PPT1 inhibition enhances the antitumor activity of anti-PD-1 antibody in melanoma Sharma, Gaurav; Ojha, Rani; Noguera-Ortega, Estela; Rebecca, Vito W.; Attanasio, John; Liu, Shujing; Piao, Shengfu; Lee, Jennifer J.; Nicastri, Michael C.; Harper, Sandra L.; Ronghe, Amruta; Jain, Vaibhav; Winkler, Jeffrey D.; Speicher, David W.; Mastio, Jerome; Gimotty, Phyllis A.; Xu, Xiaowei; Wherry, E. John; Gabrilovich, Dmitry, I; Amaravadi, Ravi K. 分享 收藏
Impaired Redox and Protein Homeostasis as Risk Factors and Therapeutic Targets in Toxin-Induced Biliary Atresia Zhao, Xiao; Lorent, Kristin; Escobar-Zarate, Diana; Rajagopalan, Ramakrishnan; Loomes, Kathleen M.; Gillespie, Kevin; Mesaros, Clementina; Estrada, Michelle A.; Blair, Ian A.; Winkler, Jeffrey D.; Spinner, Nancy B.; Devoto, Marcella; Pack, Michael 分享 收藏
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A 3-(4-nitronaphthen-1-yl) amino-benzoate analog as a bifunctional AKR1C3 inhibitor and AR antagonist: Head to head comparison with other advanced AKR1C3 targeted therapeutics 作为双功能AKR1C3抑制剂和AR拮抗剂的3-(4-硝基萘-1-基) 氨基-苯甲酸酯类似物: 与其他高级AKR1C3靶向疗法的头对头比较 Wangtrakuldee, Phumvadee; Adeniji, Adegoke O.; Zang, Tianzhu; Duan, Ling; Khatri, Buddha; Twenter, Barry M.; Estrada, Michelle A.; Higgins, Tyler F.; Winkler, Jeffrey D.; Penning, Trevor M. 分享 收藏
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PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer Rebecca, Vito W.; Nicastri, Michael C.; Fennelly, Colin; Chude, Cynthia I.; Barber-Rotenberg, Julie S.; Ronghe, Amruta; McAfee, Quentin; McLaughlin, Noel P.; Zhang, Gao; Goldman, Aaron R.; Ojha, Rani; Piao, Shengfu; Noguera-Ortega, Estela; Martorella, Alessandra; Alicea, Gretchen M.; Lee, Jennifer J.; Schuchter, Lynn M.; Xu, Xiaowei; Herlyn, Meenhard; Marmorstein, Ronen; Gimotty, Phyllis A.; Speicher, David W.; Winkler, Jeffrey D.; Amaravadi, Ravi K. 分享 收藏
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors Baquero, Pablo; Dawson, Amy; Mukhopadhyay, Arunima; Kuntz, Elodie M.; Mitchell, Rebecca; Olivares, Orianne; Lanniciello, Angela; Scott, Mary T.; Dunn, Karen; Nicastri, Michael C.; Winkler, Jeffrey D.; Michie, Alison M.; Ryan, Kevin M.; Halsey, Christina; Gottlieb, Eyal; Keaney, Erin P.; Murphy, Leon O.; Amaravadi, Ravi K.; Holyoake, Tessa L.; Helgason, G. Vignir 分享 收藏
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Synthesis and Structure-Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia Estrada, Michelle A.; Zhao, Xiao; Lorent, Kristin; Kriegermeier, Alyssa; Nagao, Seika A.; Berritt, Simon; Wells, Rebecca G.; Pack, Michael; Winkler, Jeffrey D. 分享 收藏
A Unified Approach to Targeting the Lysosome's Degradative and Growth Signaling Roles Rebecca, Vito W.; Nicastri, Michael C.; McLaughlin, Noel; Fennelly, Colin; McAfee, Quentin; Ronghe, Amruta; Nofal, Michel; Lim, Chun-Yan; Witze, Eric; Chude, Cynthia I.; Zhang, Gao; Alicea, Gretchen M.; Piao, Shengfu; Murugan, Sengottuvelan; Ojha, Rani; Levi, Samuel M.; Wei, Zhi; Barber-Rotenberg, Julie S.; Murphy, Maureen E.; Mills, Gordon B.; Lu, Yiling; Rabinowitz, Joshua; Marmorstein, Ronen; Liu, Qin; Liu, Shujing; Xu, Xiaowei; Herlyn, Meenhard; Zoncu, Roberto; Brady, Donita C.; Speicher, David W.; Winkler, Jeffrey D.; Amaravadi, Ravi K. 分享 收藏
ATG5 Mediates a Positive Feedback Loop between Wnt Signaling and Autophagy in Melanoma Ndoye, Abibatou; Budina-Kolomets, Anna; Kugel, Curtis H., III; Webster, Marie R.; Kaur, Amanpreet; Behera, Reeti; Rebecca, Vito W.; Li, Ling; Brafford, Patricia A.; Liu, Qin; Gopal, Y. N. Vashisht; Davies, Michael A.; Mills, Gordon B.; Xu, Xiaowei; Wu, Hong; Herlyn, Meenhard; Nicastri, Michael C.; Winkler, Jeffrey D.; Soengas, Maria S.; Amaravadi, Ravi K.; Murphy, Maureen E.; Weeraratna, Ashani T. 分享 收藏
ALDH1A1 and HLTF modulate the activity of lysosomal autophagy inhibitors in cancer cells Piao, Shengfu; Ojha, Rani; Rebecca, Vito W.; Samanta, Arabinda; Ma, Xiao-hong; Mcafee, Quentin; Nicastri, Michael C.; Buckley, Meghan; Brown, Eric; Winkler, Jeffrey D.; Gimotty, Phyllis A.; Amaravadi, Ravi K. 分享 收藏
CDK4/6 and autophagy inhibitors synergistically induce senescence in Rb positive cytoplasmic cyclin E negative cancers Vijayaraghavan, Smruthi; Karakas, Cansu; Doostan, Iman; Chen, Xian; Bui, Tuyen; Yi, Min; Raghavendra, Akshara S.; Zhao, Yang; Bashour, Sami I.; Ibrahim, Nuhad K.; Karuturi, Meghan; Wang, Jing; Winkler, Jeffrey D.; Amaravadi, Ravi K.; Hunt, Kelly K.; Tripathy, Debu; Keyomarsi, Khandan 分享 收藏
Ischemia Induces Quiescence and Autophagy Dependence in Hepatocellular Carcinoma Gade, Terence P. F.; Tucker, Elizabeth; Nakazawa, Michael S.; Hunt, Stephen J.; Wong, Waihay; Krock, Bryan; Weber, Charles N.; Nadolski, Gregory J.; Clark, Timothy W. I.; Soulen, Michael C.; Furth, Emma E.; Winkler, Jeffrey D.; Amaravadi, Ravi K.; Simon, M. Celeste 分享 收藏
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