Haig H. Kazazian - Publications, H-index & Citations

Haig H. Kazazian

Johns Hopkins University

86H指数

303论文数

3.3W被引数

收录论文 54

发表时间

ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition ZCCHC3是一种应激颗粒锌节蛋白，可强烈抑制LINE-1逆转

PLOS GENETICS

IF3.7

2023-07-05

OAAI

Goodier, John L. L.; Wan, Han; Soares, Alisha O. O.; Sanchez, Laura; Selser, John Michael; Pereira, Gavin C. C.; Karma, Sadik; Garcia-Perez, Jose Luis; Kazazian, Haig H. H.; Canadas, Marta Garcia M.

Human L1 retrotransposition:: cis preference versus trans complementation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

568

OAAI

Wei, W; Gilbert, N; Ooi, SL; Lawler, JF; Ostertag, EM; Kazazian, HH; Boeke, JD; Moran, JV

LINE-1 ORF1 protein localizes in stress granules with other RNA-Binding proteins, including components of RNA interference RNA-induced silencing complex

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

258

OAAI

Goodier, John L.; Zhang, Lili; Vetter, Melissa R.; Kazazian, Haig H., Jr.

The Minimal Active Human SVA Retrotransposon Requires Only the 5′-Hexamer and Alu-Like Domains

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

OAAI

Hancks, Dustin C.; Mandal, Prabhat K.; Cheung, Ling E.; Kazazian, Haig H., Jr.

Striking heterogeneity of somatic L1 retrotransposition in single normal and cancerous gastrointestinal cells 单个正常和癌性胃肠道细胞中体细胞L1逆转录的惊人异质性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2020-12-04

OAAI

Yamaguchi, Katsumi; Soares, Alisha O.; Goff, Loyal A.; Talasila, Anjali; Choi, Jungbin A.; Ivenitsky, Daria; Karma, Sadik; Brophy, Benjamin; Devine, Scott E.; Meltzer, Stephen J.; Kazazian, Haig H., Jr.

A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells

NATURE BIOTECHNOLOGY

IF41.7

2020-11-16

296

OAAI

Nguyen, Giang N.; Everett, John K.; Kafle, Samita; Roche, Aoife M.; Raymond, Hayley E.; Leiby, Jacob; Wood, Christian; Assenmacher, Charles-Antoine; Merricks, Elizabeth P.; Long, C. Tyler; Kazazian, Haig H.; Nichols, Timothy C.; Bushman, Frederic D.; Sabatino, Denise E.

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition 全基因组的泛癌症分析确定了由LINE-1反转录转座促进的驱动程序重排

NATURE GENETICS

IF31.8

2020-02-05

252

OAAI

Rodriguez-Martin, Bernardo; Alvarez, Eva G.; Baez-Ortega, Adrian; Zamora, Jorge; Supek, Fran; Demeulemeester, Jonas; Santamarina, Martin; Ju, Young Seok; Temes, Javier; Garcia-Souto, Daniel; Detering, Harald; Li, Yilong; Rodriguez-Castro, Jorge; Dueso-Barroso, Ana; Bruzos, Alicia L.; Dentro, Stefan C.; Blanco, Miguel G.; Contino, Gianmarco; Ardeljan, Daniel; Tojo, Marta; Roberts, Nicola D.; Zumalave, Sonia; Edwards, Paul A. W.; Weischenfeldt, Joachim; Puiggros, Montserrat; Chong, Zechen; Chen, Ken; Lee, Eunjung Alice; Wala, Jeremiah A.; Raine, Keiran; Butler, Adam; Waszak, Sebastian M.; Navarro, Fabio C. P.; Schumacher, Steven E.; Monlong, Jean; Maura, Francesco; Bolli, Niccolo; Bourque, Guillaume; Gerstein, Mark; Park, Peter J.; Wedge, David C.; Beroukhim, Rameen; Torrents, David; Korbel, Jan O.; Martincorena, Inigo; Fitzgerald, Rebecca C.; Van Loo, Peter; Kazazian, Haig H.; Burns, Kathleen H.; Campbell, Peter J.; Tubio, Jose M. C.; Akdemir, Kadir C.; Boutros, Paul C.; Bowtell, David D. L.; Brors, Benedikt; Chan, Kin; Cortes-Ciriano, Isidro; Dunford, Andrew J.; Edwards, Paul A.; Estivill, Xavier; Etemadmoghadam, Dariush; Feuerbach, Lars; Fink, J. Lynn; Frenkel-Morgenstern, Milana; Garsed, Dale W.; Gordenin, Dmitry A.; Haan, David; Haber, James E.; Hess, Julian M.; Hutter, Barbara; Imielinski, Marcin; Jones, David T. W.; Kazanov, Marat D.; Klimczak, Leszek J.; Koh, Youngil; Kumar, Kiran; Lee, Jake June-Koo; Lynch, Andy G.; Macintyre, Geoff; Markowetz, Florian; Martinez-Fundichely, Alexander; Meyerson, Matthew; Miyano, Satoru; Nakagawa, Hidewaki; Ossowski, Stephan; Pearson, John, V; Rippe, Karsten; Roberts, Steven A.; Scully, Ralph; Shackleton, Mark; Sidiropoulos, Nikos; Sieverling, Lina; Stewart, Chip; Villasante, Izar; Waddell, Nicola; Yang, Lixing; Yao, Xiaotong; Yoon, Sung-Soo; Zhang, Cheng-Zhong

Mobile DNA in Endocrinology: LINE-1 Retrotransposon Causing Partial Androgen Insensitivity Syndrome

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

IF5.1

2019-08-08

OAAI

Batista, Rafael Loch; Yamaguchi, Katsumi; Rodrigues, Andresa di Santi; Nishi, Mirian Yumie; Goodier, John L.; Carvalho, Luciani Renata; Domenice, Sorahia; Costa, Elaine M. F.; Kazazian, Haig H., Jr.; Mendonca, Berenice Bilharinho

Mobile DNA in Health and Disease

NEW ENGLAND JOURNAL OF MEDICINE

IF78.5

2017-07-27

292

OAAI

Kazazian, Haig H., Jr.; Moran, John V.

Heritable L1 retrotransposition in the mouse primordial germline and early embryo

GENOME RESEARCH

IF5.5

2017-05-08

OAAI

Richardson, Sandra R.; Gerdes, Patricia; Gerhardt, Daniel J.; Sanchez-Luque, Francisco J.; Bodea, Gabriela-Oana; Munoz-Lopez, Martin; Jesuadian, J. Samuel; Kempen, Marie-Jeanne H. C.; Carreira, Patricia E.; Jeddeloh, Jeffrey A.; Garcia-Perez, Jose L.; Kazazian, Haig H., Jr.; Ewing, Adam D.; Faulkner, Geoffrey J.

Aicardi-Goutieres syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion

NUCLEIC ACIDS RESEARCH

IF13.1

2017-03-15

OAAI

Li, Peng; Du, Juan; Goodier, John L.; Hou, Jingwei; Kang, Jian; Kazazian, Haig H., Jr.; Zhao, Ke; Yu, Xiao-Fang

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma

HUMAN MUTATION

IF3.7

2016-07-13

OAAI

Doucet-O'Hare, Tara T.; Sharma, Reema; Rodic, Nemanja; Anders, Robert A.; Burns, Kathleen H.; Kazazian, Haig H., Jr.

25 Years of Human Mutation

HUMAN MUTATION

IF3.7

2016-04-26

OAAI

Cutting, Garry R.; Kazazian, Haig H., Jr.

LINE-1 expression and retrotransposition in Barrett's esophagus and esophageal carcinoma

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-08-17

120

OAAI

Doucet-O'Hare, Tara T.; Rodic, Nemanja; Sharma, Reema; Darbari, Isha; Abril, Gabriela; Choi, Jungbin A.; Ahn, Ji Young; Cheng, Yulan; Anders, Robert A.; Burns, Kathleen H.; Meltzer, Stephen J.; Kazazian, Haig H., Jr.

Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution

GENOME RESEARCH

IF5.5

2015-08-10

106

OAAI

Ewing, Adam D.; Gacita, Anthony; Wood, Laura D.; Ma, Florence; Xing, Dongmei; Kim, Min-Sik; Manda, Srikanth S.; Abril, Gabriela; Pereira, Gavin; Makohon-Moore, Alvin; Looijenga, Leendert H. J.; Gillis, Ad J. M.; Hruban, Ralph H.; Anders, Robert A.; Romans, Katharine E.; Pandey, Akhilesh; Iacobuzio-Donahue, Christine A.; Vogelstein, Bert; Kinzler, Kenneth W.; Kazazian, Haig H., Jr.; Solyom, Szilvia

In Memoriam: Richard GH Cotton (1940-2015)

HUMAN MUTATION

IF3.7

2015-07-03

PREAI

Kazazian, Haig H., Jr.; Paalman, Mark H.; Cutting, Garry R.

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

PLOS GENETICS

IF3.7

2015-05-22

115

OAAI

Goodier, John L.; Pereira, Gavin C.; Cheung, Ling E.; Rose, Rebecca J.; Kazazian, Haig H., Jr.

Enrichment of processed pseudogene transcripts in L1-ribonucleoprotein particles

HUMAN MOLECULAR GENETICS

IF3.2

2013-05-21

OAAI

Mandal, Prabhat K.; Ewing, Adam D.; Hancks, Dustin C.; Kazazian, Haig H., Jr.

MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells

PLOS GENETICS

IF3.7

2012-10-18

192

OAAI

Goodier, John L.; Cheung, Ling E.; Kazazian, Haig H., Jr.

Extensive somatic L1 retrotransposition in colorectal tumors

GENOME RESEARCH

IF5.5

2012-09-11

228

OAAI

Solyom, Szilvia; Ewing, Adam D.; Rahrmann, Eric P.; Doucet, Tara; Nelson, Heather H.; Burns, Michael B.; Harris, Reuben S.; Sigmon, David F.; Casella, Alex; Erlanger, Bracha; Wheelan, Sarah; Upton, Kyle R.; Shukla, Ruchi; Faulkner, Geoffrey J.; Largaespada, David A.; Kazazian, Haig H.

研究方向