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Human organotypic colon in vitro microtissue: unveiling a new window into colonic drug disposition 人类器官型结肠体外微组织: 揭开结肠药物处置的新窗口 Canhao, Pedro G. M.; Snoeys, Jan; Geerinckx, Suzy; van Heerden, Marjolein; Van den Bergh, An; Holm, Camden; Markus, Jan; Ayehunie, Seyoum; Monshouwer, Mario; Evers, Raymond; Augustijns, Patrick; Kourula, Stephanie 分享 收藏
Membrane transporters in drug development and as determinants of precision medicine 药物开发中的膜转运蛋白和精准医学的决定因素 Galetin, Aleksandra; Brouwer, Kim L. R.; Tweedie, Donald; Yoshida, Kenta; Sjostedt, Noora; Aleksunes, Lauren; Chu, Xiaoyan; Evers, Raymond; Hafey, Michael J.; Lai, Yurong; Matsson, Par; Riselli, Andrew; Shen, Hong; Sparreboom, Alex; Varma, Manthena V. S.; Yang, Jia; Yang, Xinning; Yee, Sook Wah; Zamek-Gliszczynski, Maciej J.; Zhang, Lei; Giacomini, Kathleen M. 分享 收藏
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The next frontier in ADME science: Predicting transporter-based drug disposition, tissue concentrations and drug-drug interactions in humans ADME科学的下一个前沿: 预测人类基于转运蛋白的药物处置，组织浓度和药物-药物相互作用 Storelli, Flavia; Yin, Mengyue; Kumar, Aditya R.; Ladumor, Mayur K.; Evers, Raymond; Chothe, Paresh P.; Enogieru, Osatohanmwen J.; Liang, Xiaomin; Lai, Yurong; Unadkat, Jashvant D. 分享 收藏
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Regulation of Drug Transport Proteins-From Mechanisms to Clinical Impact: A White Paper on Behalf of the International Transporter Consortium 药物转运蛋白的调控-从机制到临床影响: 代表国际转运蛋白联盟的白皮书 Brouwer, Kim L. R.; Evers, Raymond; Hayden, Elizabeth; Hu, Shuiying; Li, Cindy Yanfei; zu Schwabedissen, Henriette E. Meyer; Neuhoff, Sibylle; Oswald, Stefan; Piquette-Miller, Micheline; Saran, Chitra; Sjostedt, Noora; Sprowl, Jason A.; Stahl, Simone H.; Yue, Wei 分享 收藏
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Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides (Mar, 10.1007/s11095-021-03005-z, 2021) Desai, Tanvi J.; Habulihaz, Bahanu; Cannon, Joseph R.; Chandramohan, Arun; Kaan, Hung Yi Kristal; Sadruddin, Ahmad; Yuen, Tsz Ying; Johannes, Charles; Thean, Dawn; Brown, Chris J.; Lane, David P.; Partridge, Anthony W.; Evers, Raymond; Sawyer, Tomi K.; Hochman, Jerome 分享 收藏
Liposome Click Membrane Permeability Assay for Identifying Permeable Peptides Desai, Tanvi J.; Habulihaz, Bahanu; Cannon, Joseph R.; Chandramohan, Arun; Kaan, Hung Yi Kristal; Sadruddin, Ahmad; Yuen, Tsz Ying; Johannes, Charles; Thean, Dawn; Brown, Chris J.; Lane, David P.; Partridge, Anthony W.; Evers, Raymond; Sawyer, Tomi K.; Hochman, Jerome 分享 收藏
Gefapixant does not have meaningful drug interactions with a MATE1/2K inhibitor or an OATP1B substrate Nussbaum, Jesse; Mccrea, Jacqueline; Hussain, Azher; Evers, Raymond; Ma, Bennett; Laabs, John; Rillera, Carmen; Garrett, Graigory; Li, Yun; Vallee, Marie-Helen; Panebianco, Deborah; Stoch, S. Aubrey; Iwamoto, Marian 分享 收藏
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment Tatosian, Daniel A.; Yee, Ka Lai; Zhang, Zufei; Mostoller, Kate; Paul, Erina; Sutradhar, Santosh; Larson, Patrick; Chhibber, Aparna; Wen, Jianzhong; Wang, Ya-Juan; Lassman, Michael; Latham, Andrew H.; Pang, Jianmei; Crumley, Tami; Gillespie, Anne; Marricco, Nadia Cardillo; Marenco, Ted; Murphy, Matthew; Lasseter, Kenneth C.; Marbury, Thomas C.; Tweedie, Donald; Chu, Xiaoyan; Evers, Raymond; Stoch, S. Aubrey 分享 收藏
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury Monroe, James J.; Tanis, Keith Q.; Podtelezhnikov, Alexei A.; Truyen Nguyen; Machotka, Sam, V; Lynch, Donna; Evers, Raymond; Palamanda, Jairam; Miller, Randy R.; Pippert, Todd; Cabalu, Tamara D.; Johnson, Timothy E.; Aslamkhan, Amy G.; Kang, Wen; Tamburino, Alex M.; Mitra, Kaushik; Agrawal, Nancy G. B.; Sistare, Frank D. 分享 收藏
Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity Li, Yutai; Evers, Raymond; Hafey, Michael J.; Cheon, Kyeongmi; Duong, Hong; Lynch, Donna; LaFranco-Scheuch, Lisa; Pacchione, Stephen; Tamburino, Alex M.; Tanis, Keith Q.; Geddes, Kristin; Holder, Daniel; Zhang, Nanyan Rena; Kang, Wen; Gonzalez, Raymond J.; Galijatovic-Idrizbegovic, Alema; Pearson, Kara M.; Lebron, Jose A.; Glaab, Warren E.; Sistare, Frank D. 分享 收藏
Interindividual and Regional Variability in Drug Transporter Abundance at the Human Blood-Brain Barrier Measured by Quantitative Targeted Proteomics Billington, Sarah; Salphati, Laurent; Hop, Cornelis E. C. A.; Chu, Xiaoyan; Evers, Raymond; Burdette, Doug; Rowbottom, Christopher; Lai, Yurong; Xiao, Guangqing; Humphreys, W. Griffith; Nguyen, Tot Bui; Prasad, Bhagwat; Unadkat, Jashvant D. 分享 收藏
Disease-Associated Changes in Drug Transporters May Impact the Pharmacokinetics and/or Toxicity of Drugs: A White Paper From the International Transporter Consortium Evers, Raymond; Piquette-Miller, Micheline; Polli, Joseph W.; Russel, Frans G. M.; Sprowl, Jason A.; Tohyama, Kimio; Ware, Joseph A.; de Wildt, Saskia N.; Xie, Wen; Brouwer, Kim L. R. 分享 收藏
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