未登录Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INT-787, a Novel Farnesoid X Receptor Agonist, in Healthy Volunteers: A Phase 1 Trial安全性、耐受性、药代动力学和药效学评估：INT-787（一种新型法尼酯X受体激动剂）在健康志愿者中的研究：一项Ⅰ期临床试验
Capozza, Thomas; Burkey, Jennifer; van de Wetering, Jeroen; Kerb, Reinhold; Callahan, Jennifer; Kryzhanovskaya, Ludmila; Erickson, Mary .png)
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收藏Prediction of Drug-Drug-Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic ModelingKovar, Christina; Kovar, Lukas; Ruedesheim, Simeon; Selzer, Dominik; Ganchev, Boian; Kroener, Patrick; Igel, Svitlana; Kerb, Reinhold; Schaeffeler, Elke; Muerdter, Thomas E.; Schwab, Matthias; Lehr, Thorsten 分享 收藏 分享 收藏 Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessmentFendt, Rebekka; Hofmann, Ute; Schneider, Annika R. P.; Schaeffeler, Elke; Burghaus, Rolf; Yilmaz, Ali; Blank, Lars Mathias; Kerb, Reinhold; Lippert, Joerg; Schlender, Jan-Frederik; Schwab, Matthias; Kuepfer, Lars 分享 收藏 分享 收藏 Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon加蓬甲氟喹间歇性预防疟疾的人群药代动力学Ramharter, Michael; Schwab, Matthias; Mombo-Ngoma, Ghyslain; Manego, Rella Zoleko; Akerey-Diop, Daisy; Basra, Arti; Mackanga, Jean-Rodolphe; Wuerbel, Heike; Wojtyniak, Jan-Georg; Gonzalez, Raquel; Hofmann, Ute; Geditz, Mirjam; Matsiegui, Pierre-Blaise; Kremsner, Peter G.; Menendez, Clara; Kerb, Reinhold; Lehr, Thorsten 分享 收藏 Translational learning from clinical studies predicts drug pharmacokinetics across patient populationsKrauss, Markus; Hofmann, Ute; Schafmayer, Clemens; Igel, Svitlana; Schlender, Jan; Mueller, Christian; Brosch, Mario; von Schoenfels, Witigo; Erhart, Wiebke; Schuppert, Andreas; Block, Michael; Schaeffeler, Elke; Boehmer, Gabriele; Goerlitz, Linus; Hoecker, Jan; Lippert, Joerg; Kerb, Reinhold; Hampe, Jochen; Kuepfer, Lars; Schwab, Matthias 分享 收藏 Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transportersMatthaei, Johannes; Tzvetkov, Mladen V.; Gal, Valerie; Sachse-Seeboth, Cordula; Sehrt, Daniel; Hjelmborg, Jakob B.; Hofmann, Ute; Schwab, Matthias; Kerb, Reinhold; Brockmoeller, Juergen 分享 收藏 Heritability of Caffeine Metabolism: Environmental Effects Masking Genetic Effects on CYP1A2 Activity but Not on NAT2Matthaei, J.; Tzvetkov, M. V.; Strube, J.; Sehrt, D.; Sachse-Seeboth, C.; Hjelmborg, J. B.; Moller, S.; Halekoh, U.; Hofmann, U.; Schwab, M.; Kerb, R.; Brockmoeller, J. 分享 收藏 Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled TrialKremsner, Peter G.; Adegnika, Akim A.; Hounkpatin, Aurore B.; Zinsou, Jeannot F.; Taylor, Terrie E.; Chimalizeni, Yamikani; Liomba, Alice; Kombila, Maryvonne; Bouyou-Akotet, Marielle K.; Mboumba, Denise P. Mawili; Agbenyega, Tsiri; Ansong, Daniel; Sylverken, Justice; Ogutu, Bernhards R.; Otieno, Godfrey A.; Wangwe, Anne; Bojang, Kalifa A.; Okomo, Uduak; Sanya-Isijola, Frank; Newton, Charles R.; Njuguna, Patricia; Kazungu, Michael; Kerb, Reinhold; Geditz, Mirjam; Schwab, Matthias; Velavan, Thirumalaisamy P.; Nguetse, Christian; Koehler, Carsten; Issifou, Saadou; Bolte, Stefanie; Engleitner, Thomas; Mordmueller, Benjamin; Krishna, Sanjeev 分享 收藏 Heritability of Metoprolol and Torsemide PharmacokineticsMatthaei, J.; Brockmoeller, J.; Tzvetkov, M. V.; Sehrt, D.; Sachse-Seeboth, C.; Hjelmborg, J. B.; Moeller, S.; Halekoh, U.; Hofmann, U.; Schwab, M.; Kerb, R. 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolitesMuerdter, Thomas E.; Kerb, Reinhold; Turpeinen, Miia; Schroth, Werner; Ganchev, Boian; Boehmer, Gabriele M.; Igel, Svitlana; Schaeffeler, Elke; Zanger, Ulrich; Brauch, Hiltrud; Schwab, Matthias 分享 收藏 分享 收藏 分享 收藏 Expression of Organic Cation Transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) Is Affected by Genetic Factors and Cholestasis in Human LiverNies, Anne T.; Koepsell, Hermann; Winter, Stefan; Burk, Oliver; Klein, Kathrin; Kerb, Reinhold; Zanger, Ulrich M.; Keppler, Dietrich; Schwab, Matthias; Schaeffeler, Elke 分享 收藏 分享 收藏 分享 收藏 
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