未登录 Pharmacological blockade of the mast cell MRGPRX2 receptor supports investigation of its relevance in skin disorders Macphee, Colin H.; Dong, Xinzhong; Peng, Qi; Paone, Daniel V.; Skov, Per Stahl; Baumann, Katrine; Roethke, Theresa; Goldspink, Deborah A.; Pearson, Samuel K.; Wu, Zining 分享 收藏
Discovery and SAR Study of Boronic Acid-Based Selective PDE3B Inhibitors from a Novel DNA-Encoded Library Rowley, Ann M.; Yao, Gang; Andrews, Logan; Bedermann, Aaron; Biddulph, Ross; Bingham, Ryan; Brady, Jennifer J.; Buxton, Rachel; Cecconie, Ted; Cooper, Rona; Csakai, Adam; Gao, Enoch N.; Grenier-Davies, Melissa C.; Lawler, Meghan; Lian, Yiqian; Macina, Justyna; Macphee, Colin; Marcaurelle, Lisa; Martin, John; McCormick, Patricia; Pindoria, Rekha; Rauch, Martin; Rocque, Warren; Shen, Yingnian; Shewchuk, Lisa M.; Squire, Michael; Stebbeds, Will; Tear, Westley; Wang, Xin; Ward, Paris; Xiao, Shouhua 分享 收藏
Intradermal substance P as a challenge agent in healthy individuals ten Voorde, Wouter; Akinseye, Chika; Abdisalaam, Ismahaan; Wind, Selinde; Klarenbeek, Naomi; Bergmans, Menthe; van Doorn, Martijn; Rissmann, Robert; Kaur, Rejbinder; Hotee, Sarah; Foster, Katie; Nair, Arati; Fortunato, Lea; Macphee, Colin; Mole, Sarah; Baumann, Katrine; Brigandi, Richard 分享 收藏
Diabetes status modifies the long-term effect of lipoprotein-associated phospholipase A2 on major coronary events Siddiqui, Moneeza K.; Smith, Gillian; St Jean, Pamela; Dawed, Adem Y.; Bell, Samira; Soto-Pedre, Enrique; Kennedy, Gwen; Carr, Fiona; Wallentin, Lars; White, Harvey; Macphee, Colin H.; Waterworth, Dawn; Palmer, Colin N. A. 分享 收藏
Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes Beliveau, Francois; Tarkar, Aarti; Dion, Sebastien P.; Desilets, Antoine; Ghinet, Mariana Gabriela; Boudreault, Pierre-Luc; St-Georges, Catherine; Marsault, Eric; Paone, Daniel; Collins, Jon; Macphee, Colin H.; Campobasso, Nino; Groy, Arthur; Cottom, Josh; Ouellette, Michael; Pope, Andrew J.; Leduc, Richard 分享 收藏
Community-based statins and advanced carotid plaque: Role of CD163 positive macrophages in lipoprotein-associated phospholipase A2 activity in atherosclerotic plaque 基于社区的他汀类药物和晚期颈动脉斑块: CD163阳性巨噬细胞在动脉粥样硬化斑块中脂蛋白相关磷脂酶A2活性中的作用 Otsuka, Fumiyuki; Zhao, XiaoQing; Trout, Hugh H.; Qiao, Ye; Wasserman, Bruce A.; Nakano, Masataka; Macphee, Colin H.; Brandt, Martin; Krug-Gourley, Sue; Guo, Liang; Ladich, Elena R.; Cheng, Qi; Davis, Harry R.; Finn, Aloke V.; Virmani, Renu; Kolodgie, Frank D. 分享 收藏
Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages Lp-PLA2通过损害修复性巨噬细胞的外观来拮抗心肌梗塞后的左心室愈合 He, Shun; Chousterman, Benjamin G.; Fenn, Ashley; Anzai, Atsushi; Nairz, Manfred; Brandt, Martin; Hilgendorf, Ingo; Sun, Yuan; Ye, Yu-Xiang; Iwamoto, Yoshiko; Tricot, Benoit; Weissleder, Ralph; Macphee, Colin; Libby, Peter; Nahrendorf, Matthias; Swirski, Filip K. 分享 收藏
Atherosclerotic Plaque Inflammation Varies Between Vascular Sites and Correlates With Response to Inhibition of Lipoprotein-Associated Phospholipase A2 Fenning, Robert S.; Burgert, Mark E.; Hamamdzic, Damir; Peyster, Eliot G.; Mohler, Emile R., III; Kangovi, Shreya; Jucker, Beat M.; Lenhard, Stephen C.; Macphee, Colin H.; Wilensky, Robert L. 分享 收藏
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Diabetes and Hypercholesterolemia Increase Blood-Brain Barrier Permeability and Brain Amyloid Deposition: Beneficial Effects of the LpPLA2 Inhibitor Darapladib Acharya, Nimish K.; Levin, Eli C.; Clifford, Peter M.; Han, Min; Tourtellotte, Ryan; Chamberlain, Dean; Pollaro, Michael; Coretti, Nicholas J.; Kosciuk, Mary C.; Nagele, Eric P.; DeMarshall, Cassandra; Freeman, Theresa; Shi, Yi; Guan, Chenbing; Macphee, Colin H.; Wilensky, Robert L.; Nagele, Robert G. 分享 收藏
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Pharmacological Inhibition of C-C Chemokine Receptor 2 Decreases Macrophage Infiltration in the Aortic Root of the Human C-C Chemokine Receptor 2/Apolipoprotein E-/- Mouse: Magnetic Resonance Imaging Assessment Olzinski, Alan R.; Turner, Gregory H.; Bernard, Roberta E.; Karr, Heather; Cornejo, Carla A.; Aravindhan, Karpagam; Hoang, Bao; Ringenberg, Michael A.; Qin, Pu; Goodman, Krista B.; Willette, Robert N.; Macphee, Colin H.; Jucker, Beat M.; Sehon, Clark A.; Gough, Peter J. 分享 收藏
Both the Peroxisome Proliferator-Activated Receptor δ Agonist, GW0742, and Ezetimibe Promote Reverse Cholesterol Transport in Mice by Reducing Intestinal Reabsorption of HDL-Derived Cholesterol Briand, Francois; Naik, Snehal U.; Fuki, Ilia; Millar, John S.; Macphee, Colin; Walker, Max; Billheimer, Jeffrey; Rothblat, George; Rader, Daniel J. 分享 收藏
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development Wilensky, Robert L.; Shi, Yi; Mohler, Emile R., III; Hamamdzic, Damir; Burgert, Mark E.; Li, Jun; Postle, Anthony; Fenning, Robert S.; Bollinger, James G.; Hoffman, Bryan E.; Pelchovitz, Daniel J.; Yang, Jisheng; Mirabile, Rosanna C.; Webb, Christine L.; Zhang, LeFeng; Zhang, Ping; Gelb, Michael H.; Walker, Max C.; Zalewski, Andrew; Macphee, Colin H. 分享 收藏
Site-specific atherogenic gene expression correlates with subsequent variable lesion development in coronary and peripheral vasculature Mohler, Emile R., III; Sarov-Blat, Lea; Shi, Yi; Hamamdzic, Damir; Zalewski, Andrew; MacPhee, Colin; Llano, Raul; Pelchovitz, Dan; Mainigi, Sumeet K.; Osman, Hashim; Hallman, Troy; Steplewski, Klaudia; Gertz, Zachary; Lu, Min Min; Wilensky, Robert L. 分享 收藏
Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein Davis, Bill; Koster, Grielof; Douet, Lisa J.; Scigelova, Michaela; Woffendin, Gary; Ward, Joanna M.; Smith, Alberto; Humphries, Julia; Burnand, Kevin G.; Macphee, Colin H.; Postle, Anthony D. 分享 收藏
Role of lipoprotein-associated phospholipase A2 in leukocyte activation and inflammatory responses Shi, Yi; Zhang, Ping; Zhang, LiFeng; Osman, Hashim; Mohler, Emile R., III; Macphee, Colin; Zalewski, Andrew; Postle, Anthony; Wilensky, Robert L. 分享 收藏
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