Nicholas B. La Thangue - Publications, H-index & Citations

Nicholas B. La Thangue

university of oxford

57H指数

203论文数

1.2W被引数

收录论文 49

发表时间

Sustained cancer-relevant alternative RNA splicing events driven by PRMT5 in high-risk neuroblastoma

MOLECULAR ONCOLOGY

IF4.5

2024-07-17

OAAI

Bate-Eya, Laurel Tabe; Albayrak, Gulsah; Carr, Simon Mark; Shrestha, Amit; Kanapin, Alexander; Samsonova, Anastasia; La Thangue, Nicholas Barrie

Citrullination and the protein code: crosstalk between post-translational modifications in cancer 瓜氨酸化和蛋白质代码: 癌症中翻译后修饰之间的串扰

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

IF4.7

2023-10-02

OAAI

Harada, Koyo; Carr, Simon M.; Shrestha, Amit; La Thangue, Nicholas B.

Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response

NATURE COMMUNICATIONS

IF15.7

2023-02-25

OAAI

Barczak, Wojciech; Carr, Simon M. M.; Liu, Geng; Munro, Shonagh; Nicastri, Annalisa; Lee, Lian Ni; Hutchings, Claire; Ternette, Nicola; Klenerman, Paul; Kanapin, Alexander; Samsonova, Anastasia; La Thangue, Nicholas B. B.

The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity

COMMUNICATIONS BIOLOGY

IF5.1

2023-01-26

OAAI

Liu, Geng; Barczak, Wojciech; Lee, Lian Ni; Shrestha, Amit; Provine, Nicholas M.; Albayrak, Gulsah; Zhu, Hong; Hutchings, Claire; Klenerman, Paul; La Thangue, Nicholas B.

Immune modulation underpins the anti-cancer activity of HDAC inhibitors

MOLECULAR ONCOLOGY

IF4.5

2021-05-01

OAAI

Blaszczak, Wiktoria; Liu, Geng; Zhu, Hong; Barczak, Wojciech; Shrestha, Amit; Albayrak, Gulsah; Zheng, Shunsheng; Kerr, David; Samsonova, Anastasia; La Thangue, Nicholas B.

PRMT5 promotes cancer cell migration and invasion through the E2F pathway

CELL DEATH & DISEASE

IF9.6

2020-07-24

OAAI

Barczak, Wojciech; Jin, Li; Carr, Simon Mark; Munro, Shonagh; Ward, Samuel; Kanapin, Alexander; Samsonova, Anastasia; La Thangue, Nicholas B.

Arginine methylation expands the regulatory mechanisms and extends the genomic landscape under E2F control

SCIENCE ADVANCES

IF12.5

2019-06-01

OAAI

Roworth, Alice Poppy; Carr, Simon Mark; Liu, Geng; Barczak, Wojciech; Miller, Rebecca Louise; Munro, Shonagh; Kanapin, Alexander; Samsonova, Anastasia; La Thangue, Nicholas B.

Functional interplay between E2F7 and ribosomal rRNA gene transcription regulates protein synthesis

CELL DEATH & DISEASE

IF9.6

2018-05-14

OAAI

Coutts, Amanda S.; Munro, Shonagh; La Thangue, Nicholas B.

Tudor-domain protein PHF20L1 reads lysine methylated retinoblastoma tumour suppressor protein

CELL DEATH AND DIFFERENTIATION

IF15.4

2017-08-25

OAAI

Carr, Simon M.; Munro, Shonagh; Sagum, Cari A.; Fedorov, Oleg; Bedford, Mark T.; La Thangue, Nicholas B.

Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function

CELL REPORTS

IF6.9

2017-06-01

OAAI

Munro, Shonagh; Hookway, Edward S.; Floderer, Melanie; Carr, Simon M.; Konietzny, Rebecca; Kessler, Benedikt M.; Oppermann, Udo; La Thangue, Nicholas B.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

CELL CHEMICAL BIOLOGY

IF7.2

2017-03-01

122

OAAI

Tumber, Anthony; Nuzzi, Andrea; Hookway, Edward S.; Hatch, Stephanie B.; Velupillai, Srikannathasan; Johansson, Catrine; Kawamura, Akane; Savitsky, Pavel; Yapp, Clarence; Szykowska, Aleksandra; Wu, Na; Bountra, Chas; Strain-Damerell, Claire; Burgess-Brown, Nicola A.; Ruda, Gian Filippo; Fedorov, Oleg; Munro, Shonagh; England, Katherine S.; Nowak, Radoslaw P.; Schofield, Christopher J.; La Thangue, Nicholas B.; Pawlyn, Charlotte; Davies, Faith; Morgan, Gareth; Athanasou, Nick; Mueller, Susanne; Oppermann, Udo; Brennan, Paul E.

CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation

CELL CHEMICAL BIOLOGY

IF7.2

2017-01-01

OAAI

Olzscha, Heidi; Fedorov, Oleg; Kessler, Benedikt M.; Knapp, Stefan; La Thangue, Nicholas B.

TLR Adaptor Protein MYD88 Mediates Sensitivity to HDAC Inhibitors via a Cytokine-Dependent Mechanism

CANCER RESEARCH

IF16.6

2016-11-30

OAAI

New, Maria; Sheikh, Semira; Bekheet, Mina; Olzscha, Heidi; Thezenas, Marie-Laetitia; Care, Matthew A.; Fotheringham, Susan; Tooze, Reuben M.; Kessler, Benedikt; La Thangue, Nicholas B.

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses

SCIENTIFIC REPORTS

IF3.9

2016-05-23

OAAI

Kawalkowska, Joanna; Quirke, Anne-Marie; Ghari, Fatemeh; Davis, Simon; Subramanian, Venkataraman; Thompson, Paul R.; Williams, Richard O.; Fischer, Roman; La Thangue, Nicholas B.; Venables, Patrick J.

Regulation of actin nucleation and autophagosome formation

CELLULAR AND MOLECULAR LIFE SCIENCES

IF6.2

2016-05-04

OAAI

Coutts, Amanda S.; La Thangue, Nicholas B.

Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response

SCIENCE ADVANCES

IF12.5

2016-02-05

OAAI

Ghari, Fatemeh; Quirke, Anne-Marie; Munro, Shonagh; Kawalkowska, Joanna; Picaud, Sarah; McGouran, Joanna; Subramanian, Venkataraman; Muth, Aaron; Williams, Richard; Kessler, Benedikt; Thompson, Paul R.; Fillipakopoulos, Panagis; Knapp, Stefan; Venables, Patrick J.; La Thangue, Nicholas B.

WEE1 inhibition selectively kills histone H3K36me3-deficient cancers by dNTP starvation

CANCER RESEARCH

IF16.6

2016-01-14

PREAI

Pfister, Sophia X.; Markkanen, Enni; Jiang, Yanyan; Sarkar, Sovan; Woodcock, Mick; Zalmas, Lykourgos-Panagiotis; Orlando, Giulia; Drobnitzky, Neele; Dianov, Grigory; Ying, Songmin; La Thangue, Nicholas B.; D'Angiolella, Vincenzo; Ryan, Anderson; Humphrey, Timothy C.

Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy

CANCER RESEARCH

IF16.6

2015-11-30

201

OAAI

Picaud, Sarah; Fedorov, Oleg; Thanasopoulou, Angeliki; Leonards, Katharina; Jones, Katherine; Meier, Julia; Olzscha, Heidi; Monteiro, Octovia; Martin, Sarah; Philpott, Martin; Tumber, Anthony; Filippakopoulos, Panagis; Yapp, Clarence; Wells, Christopher; Che, Ka Hing; Bannister, Andrew; Robson, Samuel; Kumar, Umesh; Parr, Nigel; Lee, Kevin; Lugo, Dave; Jeffrey, Philip; Taylor, Simon; Vecellio, Matteo L.; Bountra, Chas; Brennan, Paul E.; O'Mahony, Alison; Velichko, Sharlene; Mueller, Susanne; Hay, Duncan; Daniels, Danette L.; Urh, Marjeta; La Thangue, Nicholas B.; Kouzarides, Tony; Prinjha, Rab; Schwaller, Juerg; Knapp, Stefan

Post-translational control of transcription factors: methylation ranks highly

FEBS JOURNAL

IF4.2

2015-10-16

OAAI

Carr, Simon M.; Roworth, A. Poppy; Chan, Cheryl; La Thangue, Nicholas B.

Actin nucleation by WH2 domains at the autophagosome

NATURE COMMUNICATIONS

IF15.7

2015-07-30

OAAI

Coutts, Amanda S.; La Thangue, Nicholas B.

研究方向